Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Arjan Kol"'
1
Akademický článek
Development of [89Zr]Zr-hCD103.Fab01A and [68Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET
Autor: Xiaoyu Fan, Marta A. Ważyńska, Arjan Kol, Noemi Perujo Holland, Bruna Fernandes, Sander M. J. van Duijnhoven, Annechien Plat, Hans van Eenennaam, Philip H. Elsinga, Hans W. Nijman, Marco de Bruyn
Publikováno v: EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background CD103 is an integrin specifically expressed on the surface of cancer-reactive T cells. The number of CD103+ T cells significantly increases during successful immunotherapy and might therefore be an attractive biomarker for noninva
Externí odkaz: https://doaj.org/article/42504525a87d43f6acda5c05efb66f5a
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2
Akademický článek
Development of 89Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration
Autor: Danique Giesen, Hans van Eenennaam, Hans W. Nijman, Marco de Bruyn, Arjan Kol, Xiaoyu Fan, Marta A. Wazynska, Sander M.J. van Duijnhoven, Annechien Plat, Philip H. Elsinga
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Purpose CD103, an integrin specifically expressed on the surface of cancer-reactive T cells, is significantly increased during successful immunotherapy across human malignancies. In this study, we describe the generation and zirconium-89 (89Zr) radio
Externí odkaz: https://doaj.org/article/f55b3137b2b94aa192c9ac5565a27b1d
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3
Akademický článek
Combined STING levels and CD103+ T cell infiltration have significant prognostic implications for patients with cervical cancer
Autor: Arjan Kol, Joyce M. Lubbers, Anouk L.J. Terwindt, Hagma H. Workel, Annechien Plat, G. Bea A. Wisman, Joost Bart, Hans W. Nijman, Marco De Bruyn
Publikováno v: OncoImmunology, Vol 10, Iss 1 (2021)
Activation of STimulator of INterferon Genes (STING) is important for induction of anti-tumor immunity. A dysfunctional STING pathway is observed in multiple cancer types and associates with poor prognosis and inferior response to immunotherapy. Howe
Externí odkaz: https://doaj.org/article/f6ac9b82b76f4f8da7fd453704dca627
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4
Akademický článek
Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome
Autor: Kim L. Brunekreeft, Sterre T. Paijens, Maartje C.A. Wouters, Fenne L. Komdeur, Florine A. Eggink, Joyce M. Lubbers, Hagma H. Workel, Elisabeth C. Van Der Slikke, Noor E.J. Pröpper, Ninke Leffers, Julien Adam, Harry Pijper, Annechien Plat, Arjan Kol, Hans W. Nijman, Marco De Bruyn
Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)
Epithelial Ovarian cancer (EOC) is the most lethal gynecological malignancy and has limited curative therapeutic options. Immunotherapy for EOC is promising, but clinical efficacy remains restricted to a small percentage of patients. Several lines of
Externí odkaz: https://doaj.org/article/de2f887aba2643bda80bf338b00afb78
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9
Development of 89 Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration
Autor: Arjan Kol, Xiaoyu Fan, Marta A. Wazynska, Sander M.J. van Duijnhoven, Danique Giesen, Annechien Plat, Hans Van Eenennaam, Philip H. Elsinga, Hans W. Nijman, Marco de Bruyn
Publikováno v: Journal for immunotherapy of cancer, 10(12):e004877. BMC
PurposeCD103, an integrin specifically expressed on the surface of cancer-reactive T cells, is significantly increased during successful immunotherapy across human malignancies. In this study, we describe the generation and zirconium-89 (89Zr) radiol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419e259bae52c9120a812381278da943
https://research.rug.nl/en/publications/2b4bace1-7e15-40d3-93a6-75ff3d80d7d9
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10
Development of
Autor: Arjan, Kol, Xiaoyu, Fan, Marta A, Wazynska, Sander M J, van Duijnhoven, Danique, Giesen, Annechien, Plat, Hans, Van Eenennaam, Philip H, Elsinga, Hans W, Nijman, Marco, de Bruyn
Publikováno v: Journal for immunotherapy of cancer. 10(12)
CD103, an integrin specifically expressed on the surface of cancer-reactive T cells, is significantly increased during successful immunotherapy across human malignancies. In this study, we describe the generation and zirconium-89 (First, to determine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c1ec1a1522a1a7257d402aff33c413bc
https://pubmed.ncbi.nlm.nih.gov/36600560
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