Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Arja M. Band"'
Autor:
Zoltán Wiener, Jenny Högström, Ville Hyvönen, Arja M. Band, Pauliina Kallio, Tanja Holopainen, Olli Dufva, Caj Haglund, Olli Kruuna, Guillermo Oliver, Yinon Ben-Neriah, Kari Alitalo
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1943-1956 (2014)
Colorectal cancer (CRC) initiation and growth is often attributed to stem cells, yet little is known about the regulation of these cells. We show here that a subpopulation of Prox1-transcription-factor-expressing cells have stem cell activity in inte
Externí odkaz:
https://doaj.org/article/8235eee890f041a6b1f8671f4eebed38
Autor:
Yinon Ben-Neriah, Arja M. Band, Ville Hyvönen, Olli Dufva, Kari Alitalo, Zoltán Wiener, Caj Haglund, Tanja Holopainen, Guillermo Oliver, Pauliina Kallio, Jenny Högström, Olli Kruuna
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1943-1956 (2014)
SummaryColorectal cancer (CRC) initiation and growth is often attributed to stem cells, yet little is known about the regulation of these cells. We show here that a subpopulation of Prox1-transcription-factor-expressing cells have stem cell activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bdb0125fa4e364302d832578c5c7c7
Publikováno v:
Journal of Biological Chemistry. 284:35441-35449
Ski is an oncoprotein that negatively regulates transforming growth factor (TGF)-beta signaling. It acts as a transcriptional co-repressor by binding to TGF-beta signaling molecules, Smads. Efficient TGF-beta signaling is facilitated by rapid proteas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f17a96ec901e615a9e38b07307b7a7
https://doi.org/10.1074/jbc.m109.029488
https://doi.org/10.1074/jbc.m109.029488
Autor:
Daniel Louvard, Pauliina Kallio, Zoltán Wiener, Sylvie Robine, Yinon Ben-Neriah, Seppo Kaijalainen, Ville Hyvönen, Kari Alitalo, Caj Haglund, Olli Ritvos, Arja M. Band, Olli Kruuna, Jenny Högström
Publikováno v:
Proceedings of the National Academy of Sciences. 111
In the majority of microsatellite-stable colorectal cancers (CRCs), an initiating mutation occurs in the adenomatous polyposis coli (APC) or β-catenin gene, activating the β-catenin/TCF pathway. The progression of resulting adenomas is associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc7f02aa4542963ad27df101c3bc986
https://doi.org/10.1073/pnas.1406444111
https://doi.org/10.1073/pnas.1406444111
Autor:
Marikki Laiho, Arja M. Band
Estrogen receptor-α (ERα) and transforming growth factor-beta (TGF-β) signaling pathways are essential regulators during mammary gland development and tumorigenesis. Ski-related novel gene (SnoN) is an oncoprotein and a negative feedback inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2271feba0aa3f7bf918fa4aca23015de
https://europepmc.org/articles/PMC3612938/
https://europepmc.org/articles/PMC3612938/
Cysteine-rich protein 1 is regulated by transforming growth factor-β1 and expressed in lung fibrosis
Autor:
Hester Liu, Arja M. Band, Marjukka Myllärniemi, Katri Koli, Päivi M. Järvinen, Marikki Laiho, Henna M. Moore, Kaisa Salmenkivi, Outi Leppäranta, Leena Latonen
Publikováno v:
Journal of cellular physiology. 227(6)
Transforming growth factor-β (TGF-β) is a diverse cytokine regulating growth, apoptosis, differentiation, adhesion, invasion, and extracellular matrix production. Dysregulation of TGF-β is associated with fibrotic disorders and epithelial-mesenchy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854cb27e99fc87cfd969f04ee046b297
https://pubmed.ncbi.nlm.nih.gov/21882188
https://pubmed.ncbi.nlm.nih.gov/21882188
Autor:
Marikki Laiho, Arja M. Band
Publikováno v:
Journal of mammary gland biology and neoplasia. 16(2)
Estrogen receptor-α (ERα) and transforming growth factor (TGF)-β signaling pathways are major regulators during mammary gland development, function and tumorigenesis. Predominantly, they have opposing roles in proliferation and apoptosis. While ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefa46ba2d8aae88b984259e9af69a04
https://pubmed.ncbi.nlm.nih.gov/21390570
https://pubmed.ncbi.nlm.nih.gov/21390570
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1176:64-68
The stimulation of rat pancreatic islets by glucose leads both to the secretion of insulin, and the production of arachidonic acid (AA). We have previously shown that exogenous AA can stimulate insulin secretion and that this secretion was not depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c16a5ba78dcb1fd4c5ba8bc2f0ca59
https://doi.org/10.1016/0167-4889(93)90178-r
https://doi.org/10.1016/0167-4889(93)90178-r
Autor:
Arja M. Band, Mia A. Björklund, Tomi P. Mäkelä, Marikki Laiho, Kari Vaahtomeri, Karita Peltonen, Benoit Viollet
Publikováno v:
Experimental cell research. 316(5)
p27Kip1 (p27) tumour suppressor protein is regulated by multiple mechanisms including its turnover, localization and complex formation with its key targets, cyclin-dependent kinases (CDK) and cyclins. We have earlier shown that p27 exists in cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d772e34e8930364aee09c859d796af6d
https://pubmed.ncbi.nlm.nih.gov/20036235
https://pubmed.ncbi.nlm.nih.gov/20036235
Autor:
Arja M. Band, Marikki Laiho
Publikováno v:
Transforming Growth Factor-β in Cancer Therapy, Volume I ISBN: 9781588297143
Several transforming growth factor-β (TGF-β) signaling pathway proteins undergo proteasomal degradation. Controlled proteasomal degradation provides a means for the cell to time and fine-tune the duration of both positive and negative physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82d342a0b42d50025dec5dd266a50036
https://doi.org/10.1007/978-1-59745-292-2_15
https://doi.org/10.1007/978-1-59745-292-2_15