Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Arja, Ray"'
Autor:
Jason A. Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco, Xia Gao, Eugene Kim, Nathan West, Aditi Qamra, Diana Chang, Arindam Chakrabarti, David F. Choy, Alexis J. Combes, Tristan Courau, Gabriela K. Fragiadakis, Arjun Arkal Rao, Arja Ray, Jessica Tsui, Kenneth Hu, Nicholas F. Kuhn, Matthew F. Krummel, David J. Erle, Kirsten Kangelaris, Aartik Sarma, Zoe Lyon, Carolyn S. Calfee, Prescott G. Woodruff, Rajani Ghale, Eran Mick, Ashley Byrne, Beth Shoshana Zha, Charles Langelier, Carolyn M. Hendrickson, Monique G.P. van der Wijst, George C. Hartoularos, Tianna Grant, Raymund Bueno, David S. Lee, John R. Greenland, Yang Sun, Richard Perez, Anton Ogorodnikov, Alyssa Ward, Chun Jimmie Ye, Thiru Ramalingam, Jacqueline M. McBride, Fang Cai, Anastasia Teterina, Min Bao, Larry Tsai, Ivan O. Rosas, Aviv Regev, Sharookh B. Kapadia, Rebecca N. Bauer, Carrie M. Rosenberger, Yumiko Abe-Jones, Michael Adkisson, K. Mark Ansel, Saurabh Asthana, Alexander Beagle, Sharvari Bhide, Cathy Cai, Saharai Caldera, Maria Calvo, Sidney A. Carrillo, Suzanna Chak, Stephanie Christenson, Zachary Collins, Spyros Darmanis, Angela Detweiler, Catherine DeVoe, Walter Eckalbar, Jeremy Giberson, Ana Gonzalez, Gracie Gordon, Paula Hayakawa Serpa, Alejandra Jauregui, Chayse Jones, Serena Ke, Divya Kushnoor, Tasha Lea, Deanna Lee, Aleksandra Leligdowicz, Yale Liu, Salman Mahboob, Lenka Maliskova, Michael Matthay, Elizabeth McCarthy, Priscila Muñoz-Sandoval, Norma Neff, Viet Nguyen, Nishita Nigam, Randy Parada, Maira Phelps, Logan Pierce, Priya Prasad, Sadeed Rashid, Gabriella Reeder, Nicklaus Rodriguez, Bushra Samad, Andrew Schroeder, Cole Shaw, Alan Shen, Austin Sigman, Pratik Sinha, Matthew Spitzer, Sara Sunshine, Kevin Tang, Luz Torres Altamirano, Alexandra Tsitsiklis, Erden Tumurbaatar, Vaibhav Upadhyay, Alexander Whatley, Andrew Willmore, Michael Wilson, Juliane Winkler, Kristine Wong, Kimberly Yee, Michelle Yu, Mingyue Zhou, Wandi S. Zhu
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107813- (2023)
Summary: Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with acute lung injury from SARS-CoV-2 or other causes across
Externí odkaz:
https://doaj.org/article/9fcf76e7c2d9439cbd17b0a0b7fa8d89
Autor:
Arja Ray, Mackenzie K. Callaway, Nelson J. Rodríguez-Merced, Alexandra L. Crampton, Marjorie Carlson, Kenneth B. Emme, Ethan A. Ensminger, Alexander A. Kinne, Jonathan H. Schrope, Haley R. Rasmussen, Hong Jiang, David G. DeNardo, David K. Wood, Paolo P. Provenzano
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Pancreatic ductal adenocarcinoma (PDA) is an extremely metastatic and lethal disease. Here, in both murine and human PDA, we demonstrate that extracellular matrix architecture regulates cell extrusion and subsequent invasion from intact ductal struct
Externí odkaz:
https://doaj.org/article/bcdf632fadae49d698cc8059eaed9db9
Autor:
Arja Ray, Oscar Lee, Zaw Win, Rachel M. Edwards, Patrick W. Alford, Deok-Ho Kim, Paolo P. Provenzano
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Contact guidance on aligned substrates leads to directed cell migration through a poorly defined mechanism. Here the authors show that alignment of adhesion structures and F-actin generates anisotropic traction stress to drive directional migration,
Externí odkaz:
https://doaj.org/article/95889ff4ba5747cf995513288d87a844
Autor:
Matthew F. Krummel, Kip P. Conner, Dan A. Rock, Hugo Gonzalez Velozo, Arja Ray, Jordan Artichoker, Ran You
Supplementary Data from Visualizing Spatial and Stoichiometric Barriers to Bispecific T-Cell Engager Efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e2f14732c157287b0492aeffe06b7a
https://doi.org/10.1158/2326-6066.22544619.v1
https://doi.org/10.1158/2326-6066.22544619.v1
Autor:
Matthew F. Krummel, Kip P. Conner, Dan A. Rock, Hugo Gonzalez Velozo, Arja Ray, Jordan Artichoker, Ran You
Bispecific T-cell engager (BiTE) molecules are biologic T cell–directing immunotherapies. Blinatumomab is approved for treatment of B-cell malignancies, but BiTE molecule development in solid tumors has been more challenging. Here, we employed intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec3a7abb85c02ebac53e9cf6e06738f
https://doi.org/10.1158/2326-6066.c.6550704
https://doi.org/10.1158/2326-6066.c.6550704
Autor:
Ran You, Jordan Artichoker, Arja Ray, Hugo Gonzalez Velozo, Dan A. Rock, Kip P. Conner, Matthew F. Krummel
Publikováno v:
Cancer immunology research, vol 10, iss 6
Cancer Immunol Res
Cancer Immunol Res
Bispecific T-cell engager (BiTE) molecules are biologic T cell–directing immunotherapies. Blinatumomab is approved for treatment of B-cell malignancies, but BiTE molecule development in solid tumors has been more challenging. Here, we employed intr
Autor:
Kelly, Kersten, Kenneth H, Hu, Alexis J, Combes, Bushra, Samad, Tory, Harwin, Arja, Ray, Arjun Arkal, Rao, En, Cai, Kyle, Marchuk, Jordan, Artichoker, Tristan, Courau, Quanming, Shi, Julia, Belk, Ansuman T, Satpathy, Matthew F, Krummel
Publikováno v:
Cancer Cell
T cell exhaustion is a major impediment to anti-tumor immunity. However, it remains elusive how other immune cells in the tumor microenvironment (TME) contribute to this dysfunctional state. Here we show that the biology of tumor-associated macrophag
Autor:
Arja Ray, Paolo P. Provenzano
Organized extracellular matrix (ECM), in the form of aligned architectures, is a critical mediator of directed cancer cell migration by contact guidance, leading to metastasis in solid tumors. Current models suggest anisotropic force generation throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec26be9776e77bfbf7320b5606fee05
https://escholarship.org/uc/item/5zd498fq
https://escholarship.org/uc/item/5zd498fq
Autor:
Tristan Courau, Tory Harwin, Alexis J. Combes, Quanming Shi, Ansuman T. Satpathy, En Cai, Kenneth H. Hu, Arja Ray, Arjun A. Rao, Matthew F. Krummel, Kyle Marchuk, Julia A. Belk, Bushra Samad, Kelly Kersten, Jordan Artichoker
SummaryT cell exhaustion is a major impediment to anti-tumor immunity. However, it remains elusive how other immune cells in the tumor microenvironment (TME) contribute to this dysfunctional state. Here we show that the biology of tumor-associated ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb7bd942ed2f55a1d4ccf4dd093cd09
https://doi.org/10.1101/2021.09.27.461866
https://doi.org/10.1101/2021.09.27.461866
Publikováno v:
Cancer Research. 82:SY19-04
Although chronic activation is considered a major driver of T cell dysfunction in the tumor microenvironment (TME), there is a virtual absence of methodologies to discern how T cells spatiotemporally progress through activation states into that dysfu