Co-administration of metformin and gallic acid modulates JAK/STAT signaling pathway and glutathione metabolism in fructose-fed streptozotocin diabetic Rats

Autor: Elekofehinti, Olusola Olalekan, Ariyo, Esther Opeyemi, Iwaloye, Opeyemi, Obafemi, Tajudeen O

Publikováno v: In Phytomedicine Plus February 2022 2(1)

Molecular docking studies, molecular dynamics and ADME/tox reveal therapeutic potentials of STOCK1N-69160 against papain-like protease of SARS-CoV-2.

Autor: Elekofehinti, Olusola Olalekan, Iwaloye, Opeyemi, Josiah, Sunday Solomon, Lawal, Akeem Olalekan, Akinjiyan, Moses Orimoloye, Ariyo, Esther Opeyemi

Publikováno v: Molecular Diversity; Aug2021, Vol. 25 Issue 3, p1761-1773, 13p

Discovery of Traditional Chinese Medicine Derived Compounds as Wild Type and Mutant Plasmodium falciparum Dihydrofolate Reductase Inhibitors: Induced Fit Docking and ADME Studies

Autor: Iwaloye, Opeyemi, Elekofehinti, Olusola O., Kikiowo, Babatomiwa, Fadipe, Toyin Mary, Akinjiyan, Moses Orimoloye, Ariyo, Esther Opeyemi, Aiyeku, Olabisi Olapade, Adewumi, Nicholas Adeyemi

Publikováno v: Current Drug Discovery Technologies; July 2021, Vol. 18 Issue: 4 p554-569, 16p

Potential use of bitter melon (Momordica charantia) derived compounds as antidiabetics: In silico and in vivo studies.

Autor: Elekofehinti OO; Bioinformatics and Molecular Biology Units, Department of Biochemistry, Federal University of Technology, Akure, Nigeria. Electronic address: ooelekofehinti@futa.edu.ng., Ariyo EO; Bioinformatics and Molecular Biology Units, Department of Biochemistry, Federal University of Technology, Akure, Nigeria., Akinjiyan MO; Bioinformatics and Molecular Biology Units, Department of Biochemistry, Federal University of Technology, Akure, Nigeria., Olayeriju OS; Bioinformatics and Molecular Biology Units, Department of Biochemistry, Federal University of Technology, Akure, Nigeria., Lawal AO; Bioinformatics and Molecular Biology Units, Department of Biochemistry, Federal University of Technology, Akure, Nigeria., Adanlawo IG; Ekiti State University, Ado Ekiti, Nigeria., Rocha JBT; Bioquimica Toxicologia, Departmento de Quimica, CCNE, Universidade Federal de Santa Maria, RS, 97105-900 Brazil.

Publikováno v: Pathophysiology : the official journal of the International Society for Pathophysiology [Pathophysiology] 2018 Dec; Vol. 25 (4), pp. 327-333.