Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aritz Lopategi"'
Autor:
Verónica García-Alonso, Esther Titos, Jose Alcaraz-Quiles, Bibiana Rius, Aritz Lopategi, Cristina López-Vicario, Per-Johan Jakobsson, Salvadora Delgado, Juanjo Lozano, Joan Clària
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153751 (2016)
Obesity induces white adipose tissue (WAT) dysfunction characterized by unremitting inflammation and fibrosis, impaired adaptive thermogenesis and increased lipolysis. Prostaglandins (PGs) are powerful lipid mediators that influence the homeostasis o
Externí odkaz:
https://doaj.org/article/846c5acf5e7e434a8009be6d308ef2e1
Publikováno v:
Biomolecules & Therapeutics. 30:162-169
We utilized Fas21, a resveratrol analog, to modulate the function of hepatic stellate cells (HSCs) and liver sinusoidal endothelial cells (LSECs) during the angiogenic phase of murine liver metastasis by B16 melanoma and 51b colorectal carcinoma. Pre
Autor:
Vicente Arroyo, Andrea De Gottardi, Esther Titos, Cristina López-Vicario, Bibiana Rius, Henning Grønbæk, Aritz Lopategi, Pere Ginès, Ivo Graziadei, José Alcaraz-Quiles, Joan Clària, Mauro Bernardi, Marco Pavesi, Mireia Casulleras
Publikováno v:
Alcaraz-Quiles, J, Titos, E, Casulleras, M, Pavesi, M, López-Vicario, C, Rius, B, Lopategi, A, de Gottardi, A, Graziadei, I, Gronbaek, H, Ginès, P, Bernardi, M, Arroyo, V & Clària, J 2017, ' Polymorphisms in the IL-1 gene cluster influence systemic inflammation in patients at risk for acute-on-chronic liver failure ', Hepatology, vol. 65, no. 1, pp. 202-216 . https://doi.org/10.1002/hep.28896
Acute-on-chronic liver failure (ACLF) in cirrhosis is an increasingly recognized syndrome characterized by acute decompensation, organ failure(s) and high short-term mortality. Recent findings suggest that an overexuberant systemic inflammation plays
Autor:
Juan José Lozano, José Alcaraz-Quiles, Esther Titos, Aritz Lopategi, Marta Duran-Güell, Roger Flores-Costa, Cristina López-Vicario, Mireia Casulleras, Joan Clària, Bibiana Rius
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) are hallmarks of nonalcoholic fatty liver disease (NAFLD), which is the hepatic manifestation of the metabolic syndrome associated with obesity. The specialized p
Autor:
Raquel Urtasun, Natalia Nieto, Yongke Lu, Xiaodong Ge, Tung Ming Leung, Aritz Lopategi, Maria Isabel Fiel, Xiaodong Wang, Naoto Kitamura
Publikováno v:
Gut. 63:1805-1818
Objective In human chronic liver disease, there is association between ductular reaction (DR) and fibrosis; yet, the mechanism triggering its onset and its role in scar formation remains unknown. Since we previously showed that osteopontin (OPN) is h
Autor:
Charles N. Serhan, Vicente Arroyo, Juan José Lozano, Esther Titos, Bibiana Rius, José Alcaraz-Quiles, Salvadora Delgado, Verónica García-Alonso, Joan Clària, Jesmond Dalli, Aritz Lopategi, Cristina López-Vicario
Persistent activation of the innate immune system greatly influences the risk of developing metabolic complications associated with obesity. In this study, we explored the therapeutic potential of the specialized pro-resolving mediator (SPM) resolvin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a422c36c93fe32afb788d36eb92857c
https://europepmc.org/articles/PMC5101161/
https://europepmc.org/articles/PMC5101161/
Autor:
Tung Ming Leung, Natalia Nieto, Raquel Urtasun, Xiaodong Ge, Joseph George, Maria Isabel Fiel, Xiaodong Wang, Yongke Lu, Aritz Lopategi
Publikováno v:
Hepatology. 55:594-608
A key feature in the pathogenesis of liver fibrosis is fibrillar Collagen-I deposition; yet, mediators that could be key therapeutic targets remain elusive. We hypothesized that osteopontin (OPN), an extracellular matrix (ECM) cytokine expressed in h
Autor:
Esther Titos, Joan Clària, José Alcaraz-Quiles, Verónica García-Alonso, Bibiana Rius, Aritz Lopategi, Cristina López-Vicario
Publikováno v:
European journal of pharmacology. 785
A novel genus of pro-resolving lipid mediators endogenously generated from omega-3 polyunsaturated fatty acids has been identified in exudates obtained during the resolution phase of acute inflammation. The term specialized pro-resolving mediators (S
Autor:
José Alcaraz-Quiles, Sung H. Hwang, Bruce D. Hammock, Cristina López-Vicario, Vicente Arroyo, Aritz Lopategi, Bibiana Rius, Esther Titos, Verónica García-Alonso, Joan Clària
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 2
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 2
Recercat. Dipósit de la Recerca de Catalunya
instname
Soluble epoxide hydrolase (sEH) is an emerging therapeutic target in a number of diseases that have inflammation as a common underlying cause. sEH limits tissue levels of cytochrome P450 (CYP) epoxides derived from omega-6 and omega-3 polyunsaturated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a466140994c67c80fecf88b660a2cbf7
https://europepmc.org/articles/PMC4299190/
https://europepmc.org/articles/PMC4299190/
Autor:
Aritz Lopategi, Ioana Abraham-Enachescu, Tung Ming Leung, Elena Arriazu, Francisco Javier Cubero, María P. Pérez de Obanos, Aitor Benedicto, Natalia Nieto, Marina Ruiz de Galarreta, Marta Varela-Rey
Publikováno v:
Antioxidantsredox signaling. 21(7)
Significance: The extracellular matrix (ECM) is a dynamic microenvironment that undergoes continuous remodeling, particularly during injury and wound healing. Chronic liver injury of many different etiologies such as viral hepatitis, alcohol abuse, d