Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aristidis Sachpatzidis"'
Autor:
Jimin Wang, Aristidis Sachpatzidis, Thomas D. Christian, Ivan B. Lomakin, Alan Garen, William H. Konigsberg
Publikováno v:
Biochemistry. 61(17)
Human polypyrimidine-binding splicing factor (PSF/SFPQ) is a tumor suppressor protein that regulates the gene expression of several proto-oncogenes and binds to the 5'-polyuridine negative-sense template (5'-PUN) of some RNA viruses. The activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3ec37bbdebdc796c27dc520fca7a69
https://pubmed.ncbi.nlm.nih.gov/35998361
https://pubmed.ncbi.nlm.nih.gov/35998361
Autor:
Amom Ruhikanta Meetei, Andrew J. Pierce, Xiaofeng Zheng, Dorina Saro, Patrick Sung, Yong Xiong, Chang hu Du, Aristidis Sachpatzidis, Thiyam Ramsing Singh, Kebola Wahengbam, Michael W. Killen, Abdullah Mahmood Ali
Publikováno v:
Molecular Cell. 37(6):879-886
FANCM is a Fanconi anemia nuclear core complex protein required for the functional integrity of the FANC-BRCA pathway of DNA damage response and repair. Here we report the isolation and characterization of two histone-fold-containing FANCM-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c0f17dffe3a5197e5d84acbfceecd1
Autor:
Yong Xiong, Dorina Saro, Lynne Regan, Miaw Sheue Tsai, D. J. Schlingman, Patrick Sung, Aristidis Sachpatzidis, Amom Ruhikanta Meetei, Thiyam Ramsing Singh, A. H. Mack, Xiaofeng Zheng, Simon G. J. Mochrie, Qi Zhao
Publikováno v:
Nature Communications. 5
The conserved MHF1-MHF2 (MHF) complex functions in the activation of the Fanconi anemia (FA) pathway of DNA damage response, in regulating homologous recombination, and in DNA replication fork maintenance. MHF facilitates the processing of multiple t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8685959b275dbee0119ed4bc6cd13395
https://doi.org/10.1038/ncomms3987
https://doi.org/10.1038/ncomms3987
Autor:
Barry I. Schweitzer, Weiping Shao, Jill Wilken, Elias Lolis, Darren A. Thompson, Aristidis Sachpatzidis, Elias J. Fernandez
Publikováno v:
European Journal of Biochemistry. 268:2948-2959
Human herpesvirus-8 (HHV-8) is the infectious agent responsible for Kaposi’s sarcoma and encodes a protein, macrophage inflammatory protein-II (vMIP-II), which shows sequence similarity to the human CC chemokines. vMIP-II has broad receptor specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e003d29022afd4ab7a28d0c48b80414
https://doi.org/10.1046/j.1432-1327.2001.02184.x
https://doi.org/10.1046/j.1432-1327.2001.02184.x
Autor:
Thiyam Ramsing Singh, Dorina Saro, Aristidis Sachpatzidis, Xiaofeng Zheng, Yong Xiong, Patrick Sung, Amom Ruhikanta Meetei
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a43d72cf1650149b7e7e255b20ea1993
https://doi.org/10.1096/fasebj.26.1_supplement.536.8
https://doi.org/10.1096/fasebj.26.1_supplement.536.8
Autor:
Elias Lolis, Aristidis Sachpatzidis, Yoonsang Cho, James W. Murphy, Michael E. Hodsdon, Chengpeng Fan
CXCL12 (SDF-1alpha) and CXCR4 are critical for embryonic development and cellular migration in adults. These proteins are involved in HIV-1 infection, cancer metastasis, and WHIM disease. Sequestration and presentation of CXCL12 to CXCR4 by glycosami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bcc3362ae8c289d463f9c517937baf
https://europepmc.org/articles/PMC3684283/
https://europepmc.org/articles/PMC3684283/
Autor:
Aristidis Sachpatzidis, Benjamin K. Benton, John P. Manfredi, Hua Wang, Andrew Hamilton, Henrik G. Dohlman, Elias Lolis
Publikováno v:
The Journal of biological chemistry. 278(2)
The chemokine receptor CXCR4 is a co-receptor for T-tropic strains of HIV-1. A number of small molecule antagonists of CXCR4 are in development but all are likely to lead to adverse effects due to the physiological function of CXCR4. To prevent these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a252b26d0aa485d131479e5b3a662fca
https://pubmed.ncbi.nlm.nih.gov/12417595
https://pubmed.ncbi.nlm.nih.gov/12417595
The CXC subfamily of chemokines plays an important role in diverse processes, including inflammation, wound healing, growth regulation, angiogenesis, and tumorigenesis. The CXC chemokine CXCL1, or MGSA/GROalpha, is traditionally considered to be resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ad41c00bce2f0213942149a6411576
https://europepmc.org/articles/PMC2668253/
https://europepmc.org/articles/PMC2668253/
Autor:
Karen S. Anderson, Jodi B. Lubetsky, Aristidis Sachpatzidis, Po-Huang Liang, Chris Dealwis, Elias Lolis
Publikováno v:
Biochemistry. 38(39)
In an effort to use a structure-based approach for the design of new herbicides, the crystal structures of complexes of tryptophan synthase with a series of phosphonate enzyme inhibitors were determined at 2.3 A or higher resolution. These inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62c6ea6c2a41194099b4a62a374744e
https://pubmed.ncbi.nlm.nih.gov/10504236
https://pubmed.ncbi.nlm.nih.gov/10504236
Publikováno v:
The Journal of biological chemistry. 272(45)
Twenty residues in the third transmembrane domain of the serotonin transporter (SERT) were mutated, one at a time, to cysteine. Almost all of these mutants were fully active for serotonin (5-HT) transport and insensitive to inactivation by the positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfd7202e65095cb36621cd4017a4718
https://pubmed.ncbi.nlm.nih.gov/9353288
https://pubmed.ncbi.nlm.nih.gov/9353288