Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aristeidis Sfakianos"'
Autor:
Stefano Grosso, Alberto Marini, Katarina Gyuraszova, Johan Vande Voorde, Aristeidis Sfakianos, Gavin D. Garland, Angela Rubio Tenor, Ryan Mordue, Tanya Chernova, Nobu Morone, Marco Sereno, Claire P. Smith, Leah Officer, Pooyeh Farahmand, Claire Rooney, David Sumpton, Madhumita Das, Ana Teodósio, Catherine Ficken, Maria Guerra Martin, Ruth V. Spriggs, Xiao-Ming Sun, Martin Bushell, Owen J. Sansom, Daniel Murphy, Marion MacFarlane, John P. C. Le Quesne, Anne E. Willis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Treating malignant pleural mesothelioma (MpM) is challenging due to a lack of druggable genes, but other molecular features could be clinically useful. Here the authors profile mRNA translation dysregulation in MpM cell lines using polysome profiling
Externí odkaz:
https://doaj.org/article/7e118ded480445418fbb52706c703037
Autor:
John R. P. Knight, Gavin Garland, Tuija Pöyry, Emma Mead, Nikola Vlahov, Aristeidis Sfakianos, Stefano Grosso, Fabio De-Lima-Hedayioglu, Giovanna R. Mallucci, Tobias von der Haar, C. Mark Smales, Owen J. Sansom, Anne E. Willis
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 3 (2020)
Regulation of protein synthesis makes a major contribution to post-transcriptional control pathways. During disease, or under stress, cells initiate processes to reprogramme protein synthesis and thus orchestrate the appropriate cellular response. Re
Externí odkaz:
https://doaj.org/article/a2935a80c20d4745bd899b8125296c87
Publikováno v:
Seminars in Cancer Biology. 86:151-165
In tumourigenesis, oncogenes or dysregulated tumour suppressor genes alter the canonical translation machinery leading to a reprogramming of the translatome that, in turn, promotes the translation of selected mRNAs encoding proteins involved in proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9488ab0192ff02da88a759dccd9d1c
https://doi.org/10.1016/j.semcancer.2022.04.006
https://doi.org/10.1016/j.semcancer.2022.04.006