Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aristeidis P, Sfakianos"'
Autor:
Anne E. Willis, Ana Teodósio, Katarina Gyuraszova, Xiao-Ming Sun, Claire Smith, Ryan Mordue, Marco Sereno, Leah Officer, Claire Rooney, David Sumpton, Pooyeh Farahmand, Angela Rubio Tenor, Owen J. Sansom, Aristeidis P. Sfakianos, Johan Vande Voorde, Maria Guerra Martin, Gavin D. Garland, Madhumita Das, Ruth V. Spriggs, Tanya Chernova, Catherine Ficken, Alberto Marini, Marion MacFarlane, Daniel J. Murphy, Stefano Grosso, Nobu Morone, Martin Bushell, John Le Quesne
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
Malignant mesothelioma (MpM) is an aggressive, invariably fatal tumour that is causally linked with asbestos exposure. The disease primarily results from loss of tumour suppressor gene function and there are no ‘druggable’ driver oncogenes associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4634317d1a5eaacf6a942213133b30e4
https://eprints.gla.ac.uk/248582/1/248582.pdf
https://eprints.gla.ac.uk/248582/1/248582.pdf
Autor:
Ioannis Anestopoulos, Aristeidis P. Sfakianos, Rodrigo Franco, Katerina Chlichlia, Mihalis I. Panayiotidis, David J. Kroll, Aglaia Pappa
Publikováno v:
Molecules, Vol 22, Iss 1, p 62 (2016)
Silibinin, extracted from milk thistle (Silybum marianum L.), has exhibited considerable preclinical activity against prostate carcinoma. Its antitumor and chemopreventive activities have been associated with diverse effects on cell cycle, apoptosis,
Externí odkaz:
https://doaj.org/article/0b4f3d4fa5ba435485d622a93ea0d391
Autor:
Anne E. Willis, John R. P. Knight, Tuija Pöyry, Tobias von der Haar, Giovanna R. Mallucci, Emma J. Mead, Stefano Grosso, Nikola Vlahov, Owen J. Sansom, Gavin D. Garland, Fabio De-Lima-Hedayioglu, C. Mark Smales, Aristeidis P. Sfakianos
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 3 (2020)
Disease Models & Mechanisms
Disease Models & Mechanisms
Regulation of protein synthesis makes a major contribution to post-transcriptional control pathways. During disease, or under stress, cells initiate processes to reprogramme protein synthesis and thus orchestrate the appropriate cellular response. Re
Autor:
Manasa Ramakrishna, Aristeidis P. Sfakianos, Gavin D. Garland, Thomas E. Mulroney, Robert F. Harvey, Mariavittoria Pizzinga, Veronica Dezi, Tuija Pöyry, Ryan Mordue, Anne E. Willis, Mie Monti
Publikováno v:
WIREs RNA. 11
Following cell stress, a wide range of molecular pathways are initiated to orchestrate the stress response and enable adaptation to an environmental or intracellular perturbation. The post-transcriptional regulation strategies adopted during the stre
Autor:
Rodrigo Franco, Stavros Vasileiadis, S Perente, Ioannis Anestopoulos, Melina Mitsiogianni, Constantinos Simopoulos, Theodora Mantso, Aglaia Pappa, Aithne Atkinson, Mihalis I. Panayiotidis, Sotirios Botaitis, Aristeidis P. Sfakianos
Publikováno v:
Europe PubMed Central
Background: Isothiocyanates are constituents of cruciferous vegetables which have been associated with reduced cancer risk partially through their ability to induce apoptosis in malignant cells including melanoma. \ud \ud Materials and Methods: We ha
Autor:
Aristeidis P. Sfakianos, Alan J. Whitmarsh, Laura E. Mellor, Mark P. Ashe, Hope Needs, Laurent Désaubry, Yoke Fei Pang, Hussein Abou-Hamdan, Gino B. Poulin, Paraskevi Kritsiligkou
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, 2019, ⟨10.1038/s41418-019-0438-y⟩
Cell Death and Differentiation, Nature Publishing Group, 2019, ⟨10.1038/s41418-019-0438-y⟩
Cell Death and Differentiation, 2019, ⟨10.1038/s41418-019-0438-y⟩
Cell Death and Differentiation, Nature Publishing Group, 2019, ⟨10.1038/s41418-019-0438-y⟩
Stress granules are cytoplasmic mRNA-protein complexes that form upon the inhibition of translation initiation and promote cell survival in response to environmental insults. However, they are often associated with pathologies, including neurodegener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194a9ce72630c059d48936e3ff3724a4
https://hal.science/hal-02361047
https://hal.science/hal-02361047
Autor:
Rodrigo Franco, Mihalis I. Panayiotidis, Aristeidis P. Sfakianos, David J. Kroll, Katerina Chlichlia, Ioannis Anestopoulos, Aglaia Pappa
Publikováno v:
Molecules, Vol 22, Iss 1, p 62 (2016)
Molecules; Volume 22; Issue 1; Pages: 62
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 1; Pages: 62
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Silibinin, extracted from milk thistle (Silybum marianum L.), has exhibited considerable preclinical activity against prostate carcinoma. Its antitumor and chemopreventive activities have been associated with diverse effects on cell cycle, apoptosis,
Publikováno v:
Biochemical Society transactions. 44(5)
Intracellular compartments are necessary for the regulation of many biochemical processes that ensure cell survival, growth and proliferation. Compartmentalisation is commonly achieved in organelles with defined lipid membranes, such as mitochondria,