Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Arissa C. Young"'
Autor:
Grant R Williams, Douglas B Johnson, Arissa C Young, Henry T Quach, Haocan Song, Elizabeth J Davis, Javid J Moslehi, Fei Ye
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immune checkpoint inhibitors (ICIs) have transformed treatment for melanoma, but identifying reliable biomarkers of response and effective modifiable lifestyle factors has been challenging. Obesity has been correlated with improved respons
Externí odkaz:
https://doaj.org/article/6dbe377bca014a8e9c17dfb7bb086289
Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus
Autor:
Kelsey Voss, Allison E. Sewell, Evan S. Krystofiak, Katherine N. Gibson-Corley, Arissa C. Young, Jacob H. Basham, Ayaka Sugiura, Emily N. Arner, William N. Beavers, Dillon E. Kunkle, Megan E. Dickson, Gabriel A. Needle, Eric P. Skaar, W. Kimryn Rathmell, Michelle J. Ormseth, Amy S. Major, Jeffrey C. Rathmell
Publikováno v:
Science Immunology. 8
T cells in systemic lupus erythematosus (SLE) exhibit multiple metabolic abnormalities. Excess iron can impair mitochondria and may contribute to SLE. To gain insights into this potential role of iron in SLE, we performed a CRISPR screen of iron hand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec8050bf8475384d48058f8264e92df
https://doi.org/10.1126/sciimmunol.abq0178
https://doi.org/10.1126/sciimmunol.abq0178
Autor:
Kelsey Voss, Arissa C. Young, Katherine N. Gibson-Corley, Allison E. Sewell, Evan S. Krystofiak, Jacob H. Bashum, William N. Beavers, Ayaka Sugiura, Eric P. Skaar, Michelle J. Ormseth, Amy S. Major, Jeffrey C. Rathmell
T cells in systemic lupus erythematosus (SLE) exhibit mitochondrial abnormalities including elevated oxidative stress. Because excess iron can promote these phenotypes, we tested iron regulation of SLE T cells. A CRISPR screen identified Transferrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eb6ea204b8d2f75329f141dd516ccd2
https://doi.org/10.1101/2021.11.25.470053
https://doi.org/10.1101/2021.11.25.470053
