Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Arisa Igarashi"'
Autor:
Takaya Iida, Arisa Igarashi, Kae Fukunaga, Taiga Aoki, Tomomi Hidai, Kumiko Yanagi, Masahiko Yamamori, Kazuhito Satou, Hayato Go, Tomoki Kosho, Ryuto Maki, Takashi Suzuki, Yohei Nitta, Atsushi Sugie, Yoichi Asaoka, Makoto Furutani-Seiki, Tetsuaki Kimura, Yoichi Matsubara, Tadashi Kaname
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: RRAS2, a member of the R-Ras subfamily of Ras-like low-molecular-weight GTPases, is considered to regulate cell proliferation and differentiation via the RAS/MAPK signaling pathway. Seven RRAS2 pathogenic variants have been reported in
Externí odkaz:
https://doaj.org/article/be8d0351718044458620c887c218580e
Autor:
Wakiko Iwata, Hiroyuki Unoki-Kubota, Hideki Kato, Akira Shimizu, Michihiro Matsumoto, Toshiyuki Imasawa, Arisa Igarashi, Kenji Matsumoto, Tetsuo Noda, Yasuo Terauchi, Masaomi Nangaku, Masato Kasuga, Yasushi Kaburagi
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229397 (2020)
Obesity can initiate and accelerate the progression of kidney diseases. However, it remains unclear how obesity affects renal dysfunction. Here, we show that a newly generated podocyte-specific tubular sclerosis complex 2 (Tsc2) knockout mouse model
Externí odkaz:
https://doaj.org/article/2781a5cf89ec49e594b7cf2923e6bc38
Autor:
Hideki Tsumura, Morihiro Ito, Masamichi Takami, Miyuki Arai, Xiao-Kang Li, Toshio Hamatani, Arisa Igarashi, Shuji Takada, Kenji Miyado, Akihiro Umezawa, Yasuhiko Ito
Publikováno v:
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 203-210 (2016)
The CD98 heavy chain (CD98hc) regulates virus-induced cell fusion and monocyte fusion, and is involved in amino acid transportation. Here, we examined the role that CD98hc plays in the formation of osteoclasts using CD98hcflox/floxLysM-cre peritoneal
Externí odkaz:
https://doaj.org/article/d92eb2288158495182df56bfd8e661da
Autor:
Kenji Matsumoto, Kenji Miyado, Morihiro Ito, Fumihiro Sugiyama, Kazue Takeda, Miyuki Shindo, Yasuhiko Ito, Akihiro Umezawa, Arisa Igarashi, Takashi Ohkura, Hideki Tsumura
Publikováno v:
Comparative Medicine. 71:285-294
Slc1a5 (ASCT2) encodes a small neutral amino-acid exchanger and is the most well-studied glutamine transporter in cancer cells. To investigate the role of Slc1a5 in osteoclastogenesis, we developed Slc1a5-deficient mice by using a conventional gene-t
Autor:
Ichiro Takeuchi, Kumiko Yanagi, Shuji Takada, Toru Uchiyama, Arisa Igarashi, Kenichiro Motomura, Yuka Hayashi, Naoko Nagano, Ryo Matsuoka, Hiroki Sugiyama, Takako Yoshioka, Hirohisa Saito, Toshinao Kawai, Yumiko Miyaji, Yusuke Inuzuka, Yoichi Matsubara, Yukihiro Ohya, Toshiaki Shimizu, Kenji Matsumoto, Katsuhiro Arai, Ichiro Nomura, Tadashi Kaname, Hideaki Morita
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:1402-1409.e6
Allergic diseases were long considered to be complex multifactorial disorders. However, recent findings indicate that severe allergic inflammation can be caused by monogenic immune defects.This study aimed to clarify the molecular pathogenesis of a p
Autor:
Mizuho Sakaki, Yukiko Ebihara, Kohji Okamura, Kazuhiko Nakabayashi, Arisa Igarashi, Kenji Matsumoto, Kenichiro Hata, Yoshiro Kobayashi, Kayoko Maehara
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171431 (2017)
Cellular senescence is classified into two groups: replicative and premature senescence. Gene expression and epigenetic changes are reported to differ between these two groups and cell types. Normal human diploid fibroblast TIG-3 cells have often bee
Externí odkaz:
https://doaj.org/article/6af29f86204940c99dbf7da61427cdd0
Autor:
Shokei Murakami, Akio Matsuda, Takashi Inoue, Kenji Matsumoto, Kenichiro Motomura, Jun Abe, Arisa Igarashi, Masaki Miyashita
Publikováno v:
Allergy. 75:2102-2105
Autor:
Hideki, Tsumura, Miyuki, Shindo, Morihiro, Ito, Arisa, Igarashi, Kazue, Takeda, Kenji, Matsumoto, Takashi, Ohkura, Kenji, Miyado, Fumihiro, Sugiyama, Akihiro, Umezawa, Yasuhiko, Ito
Publikováno v:
Comp Med
Slc1a5 (ASCT2) encodes a small neutral amino-acid exchanger and is the most well-studied glutamine transporter in cancer cells. To investigate the role of Slc1a5 in osteoclastogenesis, we developed Slc1a5-deficient mice by using a conventional gene-t
Publikováno v:
Allergy. 76(7)
Autor:
Shuji Takada, Tempei Sato, Yoshiaki Ito, Satoshi Yamashita, Tomoko Kato, Miyuri Kawasumi, Masami Kanai-Azuma, Arisa Igarashi, Tomomi Kato, Moe Tamano, Hiroshi Asahara
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76004 (2013)
Mice are among the most valuable model animal species with an enormous amount of heritage in genetic modification studies. However, targeting genes in mice is sometimes difficult, especially for small genes, such as microRNAs (miRNAs) and targeting g
Externí odkaz:
https://doaj.org/article/9d93c94dc3e24137b401fe9c919a9933