Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Arin K. Oestreich"'
Autor:
Arin K. Oestreich, Mekka R. Garcia, Xiaomei Yao, Ferris M. Pfeiffer, Sabah Nobakhti, Sandra J. Shefelbine, Yong Wang, Amanda C. Brodeur, Charlotte L. Phillips
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 5, Iss C, Pp 3-11 (2015)
Mucopolysaccharidosis type I (MPS I), is an autosomal recessive lysosomal storage disorder caused by a deficiency in the α-L-iduronidase enzyme, resulting in decreased enzymatic activity and accumulation of glycosaminoglycans. The disorder phenotypi
Externí odkaz:
https://doaj.org/article/6ad02d00d4274b6b919708fdf62ba78d
Publikováno v:
Cell Stem Cell
Obesity disrupts physiological homeostasis and alters both systemic and local microenvironments that impact stem cell plasticity and impair regenerative capacity. We present growing evidence that reveals the bidirectionality of obesity-induced stem c
Autor:
Kathleen A Pennington, Arin K Oestreich, Kylie H Cataldo, Candace M Fogliatti, Celeste Lightner, John P Lydon, Laura C Schulz
Publikováno v:
Biology of reproduction. 107(2)
Leptin is required for fertility, including initiation of estrous cycles. It is therefore challenging to assess the role of leptin signaling during pregnancy. Although neuron-specific transgene approaches suggest that leptin signaling in the central
Publikováno v:
Mol Reprod Dev
Osteogenesis imperfecta (OI), or brittle bone disease, is most often caused by mutations in genes encoding type I collagen or proteins that process it. Women with OI have a small, but significant increase in risk of serious pregnancy complications in
Autor:
Yong Wang, Laura C. Schulz, Xiaomei Yao, Charlotte L. Phillips, Arin K. Oestreich, Anthony Onuzuriuke, Ferris M. Pfeiffer, Omonseigho O. Talton
Publikováno v:
Endocrinology
The prevalence of maternal obesity is increasing at an alarming rate and increases the life-long risk of developing cardiometabolic disease in adult offspring. Leptin, an adipokine, is systemically elevated in the obese milieu. We recently showed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dac3f359b5b52359d2a9fbb5a8d894d
https://europepmc.org/articles/PMC7417874/
https://europepmc.org/articles/PMC7417874/
Autor:
Kelle H. Moley, Sangappa B Chadchan, Alexandra Medvedeva, Francesco J. DeMayo, John P. Lydon, Marina N. Rowen, Arin K. Oestreich, Ran Xu, Pooja Popli, Claire S Stephens, Emily S. Jungheim, Ramakrishna Kommagani
Publikováno v:
Endocrinology
Uterine receptivity is critical for establishing and maintaining pregnancy. For the endometrium to become receptive, stromal cells must differentiate into decidual cells capable of secreting factors necessary for embryo survival and placental develop
Autor:
Ruhang Tang, Daniel Ferguson, Christine T.N. Pham, Charles A. Harris, Steven L. Teitelbaum, Gretchen A. Meyer, Arin K. Oestreich, Kristin L. Lenz, Yun-Rak Choi, Kelsey H. Collins, Irina Hutson, E.N. Pollitt, Farshid Guilak, Luke E. Springer
Publikováno v:
Osteoarthritis and Cartilage. 29:S14-S15
Autor:
Sangappa B Chadchan, Alexandra Medvedeva, John P. Lydon, Emily S. Jungheim, Arin K. Oestreich, Ramakrishna Kommagani, Kelle H. Moley
Publikováno v:
Biol Reprod
Successful establishment of pregnancy depends on steroid hormone-driven cellular changes in the uterus during the peri-implantation period. To become receptive to embryo implantation, uterine endometrial stromal cells (ESCs) must transdifferentiate i
Autor:
Christine T.N. Pham, Farshid Guilak, Charles A. Harris, Kristin L. Lenz, Yun-Rak Choi, Gretchen A. Meyer, Ruhang Tang, Arin K. Oestreich, Steven L. Teitelbaum, Eleanor N. Pollitt, Irina Hutson, Luke E. Springer, Daniel Ferguson, Kelsey H. Collins
Publikováno v:
Proc Natl Acad Sci U S A
Osteoarthritis (OA), the leading cause of pain and disability worldwide, disproportionally affects individuals with obesity. The mechanisms by which obesity leads to the onset and progression of OA are unclear due to the complex interactions among th
Autor:
Salah A Daghlas, Arin K. Oestreich, Xiaomei Yao, Laura C. Schulz, William M. Kamp, Yong Wang, Natalia G. Karasseva, Ferris M. Pfeiffer, Marcus G. McCray, Youngjae Jeong, Stephanie M. Carleton, Kristin L. Lenz, Charlotte L. Phillips, Mark R. Ellersieck
Publikováno v:
Proceedings of the National Academy of Sciences. 113:13522-13527
During fetal development, the uterine environment can have effects on offspring bone architecture and integrity that persist into adulthood; however, the biochemical and molecular mechanisms remain unknown. Myostatin is a negative regulator of muscle