Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Arin, Nam"'
Autor:
Erminia Massarelli, Ravi Salgia, Diana Bell, Haiqing Li, Arya Amini, Sue Chang, Atish Mohanty, Michelle Afkhami, Amanda Reyes, Rebecca Pharaon, Holly Yin, Dana Do, Arin Nam, Thomas Gernon, Robert Kang, Sagus Sampath, Prakash Kulkarni, Raju Pillai, Vicky Villaflor, Ellie Maghami
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background The study summarizes the potential use of immunotherapy for BRAF-mutated papillary thyroid cancer (PTC) by analyzing the immune profile of City of Hope PTC patient samples and comparing them to the thyroid dataset available in the TCGA dat
Externí odkaz:
https://doaj.org/article/f8577052c6e344559c40dcdf83560db4
Autor:
Linlin Guo, Atish Mohanty, Sharad Singhal, Saumya Srivastava, Arin Nam, Charles Warden, Sravani Ramisetty, Yate-Ching Yuan, Hyejin Cho, Xiwei Wu, Aimin Li, Manik Vohra, Srinivas Vinod Saladi, Deric Wheeler, Leonidas Arvanitis, Erminia Massarelli, Prakash Kulkarni, Yiming Zeng, Ravi Salgia
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107302- (2023)
Summary: This study investigates the role of integrin β4 (ITGB4) and stemness-associated factor SOX2 in platinum resistance in lung squamous cell carcinoma (LUSC). The expression of SOX2 and ITGB4 is found to be high in all LUSC subtypes, but the im
Externí odkaz:
https://doaj.org/article/9962e7214592483093812b263a3e559e
Autor:
Atish Mohanty, Arin Nam, Alex Pozhitkov, Lu Yang, Saumya Srivastava, Anusha Nathan, Xiwei Wu, Isa Mambetsariev, Michael Nelson, A.R. Subbalakshmi, Linlin Guo, Leonidas D. Arvanitis, Mohd W. Nasser, Surinder K. Batra, John Orban, Mohit Kumar Jolly, Erminia Massarelli, Prakash Kulkarni, Ravi Salgia
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101679- (2020)
Externí odkaz:
https://doaj.org/article/2fd716b72e89415eb8683e53c0f992ec
Autor:
Saumya Srivastava, Ka Ming Pang, Mari Iida, Michael S. Nelson, Jiayi Liu, Arin Nam, Jiale Wang, Isa Mambetsariev, Raju Pillai, Atish Mohanty, Nellie McDaniel, Amita Behal, Prakash Kulkarni, Deric L. Wheeler, Ravi Salgia
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101692- (2020)
Summary: The tyrosine kinase receptor ephrin receptor A2 (EPHA2) is overexpressed in lung (LSCC) and head and neck (HNSCC) squamous cell carcinomas. Although EPHA2 can inhibit tumorigenesis in a ligand-dependent fashion via phosphorylation of Y588 an
Externí odkaz:
https://doaj.org/article/862bc629bc1841d3ab9053896facbb15
Autor:
Arin Nam, Atish Mohanty, Supriyo Bhattacharya, Sourabh Kotnala, Srisairam Achuthan, Kishore Hari, Saumya Srivastava, Linlin Guo, Anusha Nathan, Rishov Chatterjee, Maneesh Jain, Mohd W. Nasser, Surinder Kumar Batra, Govindan Rangarajan, Erminia Massarelli, Herbert Levine, Mohit Kumar Jolly, Prakash Kulkarni, Ravi Salgia
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 8 (2021)
Drug resistance, a major challenge in cancer therapy, is typically attributed to mutations and genetic heterogeneity. Emerging evidence suggests that dynamic cellular interactions and group behavior also contribute to drug resistance. However, the un
Externí odkaz:
https://doaj.org/article/40e2f26bfe8e408aa3bf9e914628724d
Autor:
Tamara, Mirzapoiazova, Gang, Xiao, Bolot, Mambetsariev, Mohd W, Nasser, Emily, Miaou, Sharad S, Singhal, Saumya, Srivastava, Isa, Mambetsariev, Michael S, Nelson, Arin, Nam, Amita, Behal, Leonidas, Arvanitis, Pranita, Atri, Markus, Muschen, François L H, Tissot, James, Miser, John S, Kovach, Martin, Sattler, Surinder K, Batra, Prakash, Kulkarni, Ravi, Salgia
Publikováno v:
Mol Cancer Ther
Protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of apoptosis, proliferation, and DNA-damage response, is overexpressed in many cancers, including small cell lung cancer (SCLC). Here we report that LB100, a sma
Publikováno v:
Seminars in cancer biology. 86(Pt 2)
Lung cancer persists to contribute to one-quarter of cancer-associated deaths. Among the different histologies, non-small cell lung cancer (NSCLC) alone accounts for 85% of the cases. The development of therapies involving immune checkpoint inhibitor
Autor:
Sravani Ramisetty, Prakash Kulkarni, Supriyo Bhattacharya, Arin Nam, Sharad S. Singhal, Linlin Guo, Tamara Mirzapoiazova, Bolot Mambetsariev, Sandeep Mittan, Jyoti Malhotra, Evan Pisick, Shanmuga Subbiah, Swapnil Rajurkar, Erminia Massarelli, Ravi Salgia, Atish Mohanty
Publikováno v:
Journal of Clinical Medicine. 12:599
Translational research in medicine, defined as the transfer of knowledge and discovery from the basic sciences to the clinic, is typically achieved through interactions between members across scientific disciplines to overcome the traditional silos w
Publikováno v:
Cell Reports Medicine
Summary KRAS is a frequent oncogenic driver in solid tumors, including non-small cell lung cancer (NSCLC). It was previously thought to be an “undruggable” target due to the lack of deep binding pockets for specific small-molecule inhibitors. A b
Autor:
Jonathan Yamzon, Christina Yeon, Helen Chen, Joseph Chao, Linda D. Bosserman, Laura Kruper, Geetika Bhatt, Scott Glaser, Isaac Benjamin Paz, Denise Morse, Arin Nam, Karen Sokolov, TingTing Tan, Camille Adeimy, Bertram Yuh, Stephen Sentovich, Debbie Deaville, Prakash Kulkarni, Poornima Rao, Ravi Salgia, Deron Johnson, Elisabeth King, Amy C. Polverini, Mary Cianfrocca, Finly Zachariah, Ashley Baker Lee, Stacy W. Gray, Mina S. Sedrak
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 188, p 188 (2021)
Journal of Clinical Medicine
Journal of Clinical Medicine
As the US transitions from volume- to value-based cancer care, many cancer centers and community groups have joined to share resources to deliver measurable, high-quality cancer care and clinical research with the associated high patient satisfaction