Discovery of novel 1,8-naphthalimide piperazinamide based benzenesulfonamides derivatives as potent carbonic anhydrase IX inhibitors and ferroptosis inducers for the treatment of triple-negative breast cancer.

Autor: Liang Q; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Zhang S; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Liu J; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, China., Zhou X; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China; Department of Pharmacology and Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor., Syamimi Ariffin N; Department of Pharmacology and Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor., Wei J; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Shi C; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Ma X; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China. Electronic address: mxl78@glmc.edu.cn., Zhang Y; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China. Electronic address: zhangye81@126.com., Huang R; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China. Electronic address: rzhuang1783@163.com.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107596. Date of Electronic Publication: 2024 Jun 26.

Ocular Adnexal Manifestations of Sporotrichosis: A Report of Two Cases.

Autor: Tan L; Department of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS., Ariffin N; Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru, MYS., Vendargon FMM; Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru, MYS., Mohd Khialdin S; Department of Ophthalmology, Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.

Publikováno v: Cureus [Cureus] 2024 May 08; Vol. 16 (5), pp. e59939. Date of Electronic Publication: 2024 May 08 (Print Publication: 2024).

Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study

Autor: Barnes, Julie, Barnes, Brian, Craig, Fiona, Foster, Katharine, Greenlaw, Nicola, Harrison, Ellie, Kucyj, Sally, Maplethorpe, Alan, Mason, James, Mitchell, Eleanor, Norrie, John, Ormerod, Anthony, Shafayat, Aisha, Simpkins, Daniel, Thomas, Kim, Whitham, Diane, Williams, Hywel, Lawson, Linda, Anstey, Alex, Watkins, Catherine, Mitchell, Sarah, Goodwin, Richard, Benge, Cilla, Skibinska, Gosia, Ariffin, N., Armitt, Janice, Mguni, Nhlanhla, Masuku, Maxwell, Goodsell, Kerry, Johnson, Linda, Ingram, John, Patel, Girish, Chowdhury, Mabs, Motley, Richard, Thomas, Anne, Long, Colin, Morris, Anew, Piguet, Vincent, Kalavala, Manju, Katugampla, Ru, Blasdale, Catherine, Lateo, Stephanie, Rajan, Neil, Thomson, Anne, Natarajan, Sivakumar, Wahie, Shyamal, Sripathy, Therese, Vatve, Maneesha, Bajaj, Vrinda, Freeman, Keith, Carr, Mary, Ferguson, Adam, Riches, Katherine, Baron, Susannah, Fuller, Claire, Potter, Anthea, Brockway, Laura, Cooper, Ashley, Thompson, Susan, Duarte-Williamson, Emilia, Smith, Catherine, Minifie, Gemma, Hare, Naomi, Thornberry, Kate, Gupta, Shika, Langan, Sinead, Layton, Alison, Wray, Angela, Walker, Benjamin, Law, Gayle, Marshall, Elizabeth, Walton, Shernaz, Ashton, Katherine, Oswald, Angela, Graham, Deborah, Jones, Peter, Smith, Vanessa, Shipley, Debbie, Duggan, Claire, Jones, Sarah, Thomas, Carol, Rolls, Sally-Ann, Veysey, Emma, Meggitt, Simon, Levell, Nick, Lee, Kevin, Rakvit, Pariyawan, Millington, George, Banks-Dunnell, Karen, Chetty, Natasha, Grattan, Clive, Shah, Syed, Butcher, Donna, Nik, Marinela, Gilbanks, Kathleen, Cox, Neil, English, John, Murphy, Ruth, Perkins, William, Littlewood, Sheelagh, Bong, Jan, Malik, Moona, Batchelor, Jonathan, Wootton, Catriona, Davies-Jones, Sue, Llewellyn, Joanne, Cheng, Suzanne, Sharma, Maulina, Angus, Janet, Varma, Sandeep, Cohen, Stuart, Ogg, Graham, Burge, Susan, Venning, Vanessa, Cooper, Susan, McPherson, Tess, Matter, Lisa, Bower, Christopher, James, Robert, Velangi, Shireen, Szczecinska, Weronika, Shumba, Tinomuda, Ravenscroft, Jane, Yaakub, Azaharry, Trinh, Hong, Chapman, Anna, Miller, Natalie, Estfan, Yana, Reeves, Gwendoline, Wachsmuth, Rachel, Lewis, Victoria, Bell, Hazel, Azurdia, Richard, Walsh, Maeve, Angit, Caroline, Ngan, Kok, Young, Anea, Murgaza, Julie, Taylor, Paula, Hunter, Hamish, Martin-Clavijo, Agustin, Raghavenan, Renuga, Evriviades, Lucy, Lewis, Helen, Dunnill, Giles, Bray, Adam, De Berker, David, Johnston, Graham, McKenna, John, Shelley, Catherine, Ghazavi, Mohammad, Hill, Alison, Kirkup, Maggie, Saunders, Glenn, Lloyd-Jones, Hugh, Simmons, Dawn, Cotterill, Donna, Thomas, Kim S., Ormerod, Anthony D., Craig, Fiona E., Mason, James M., Johnston, Graham A., Williams, Hywel C.

Publikováno v: In Journal of the American Academy of Dermatology November 2016 75(5):940-949

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