Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ariele L. Greenfield"'
Autor:
Jing Zhou, Ariele L. Greenfield, Rita Loudermilk, Christopher M. Bartley, Baouyen T. Tran, Chao Zhao, Hong Wang, Michael R. Wilson, Samuel J. Pleasure
NMDA receptor antibody encephalitis (NMDAR-AE) is characterized by cerebrospinal fluid (CSF)-resident anti-NMDA receptor autoantibodies that cause a wide range of neurological manifestations. Although many symptoms are responsive to immunotherapy, be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ef0a99e98a6f370e011d3a857920c0d
https://doi.org/10.1101/2022.09.29.510196
https://doi.org/10.1101/2022.09.29.510196
Autor:
Jordan E. Bisanz, Edwina B. Tran, Patrick Barba, Ryan Baumann, Jennifer L. Gommerman, Michael R. Wilson, Lawrence R. Shiow, Jürgen Schlegel, Michael Kutza, Sergio E. Baranzini, Johanna Oechtering, James Landefeld, Jeffrey M. Gelfand, Jennifer Graves, Ryan D. Schubert, Friederike Liesche-Starnecker, Valeria Ramaglia, Lucas Schirmer, Kelsey C. Zorn, Kicheol Kim, Karin Forsberg, Stephen L. Hauser, Xiaoyuan Zhou, Jens Kuhle, Katrin Sellrie, Roland G. Henry, Khashayar Khaleghi, Akshaya Ramesh, Stephanie Vistnes, Bruce A.C. Cree, Peter M. Andersen, Peter J. Turnbaugh, Gina Kirkish, Peter H. Seeberger, Sven Wischnewski, Olga L. Rojas, Ariele L. Greenfield, Anne-Katrin Pröbstel, Ravi Dandekar, Sneha Singh, Antje Bischof
Publikováno v:
Science Immunology. 5
Changes in gut microbiota composition and a diverse role of B cells have recently been implicated in multiple sclerosis (MS), a central nervous system (CNS) autoimmune disease. Immunoglobulin A (IgA) is a key regulator at the mucosal interface. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800a2771ca9f520b72d86f2e52d86f5b
https://doi.org/10.1126/sciimmunol.abc7191
https://doi.org/10.1126/sciimmunol.abc7191
Autor:
Ariele L. Greenfield, Ravi Dandekar, Anne-Katrin Pröbstel, Edwina B. Tran, Debarko Banerji, Rita P. Loudermilk, Sergio E. Baranzini, Kicheol Kim, Joseph L. DeRisi, Michael R. Wilson, Riley Bove, Scott S. Zamvil, Joseph J. Sabatino, Ryan D. Schubert, Jeffrey M. Gelfand, Ari J. Green, Matthew T. Koelzer, Stephen L. Hauser, Chu-Yueh Guo, Kanishka Koshal, Akshaya Ramesh, Bruce A.C. Cree
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 37
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance B cells serve as a key weapon against infectious diseases. They also contribute to multiple autoimmune diseases, including multiple sclerosis (MS) where depletion of B cells is a highly effective therapy. We describe a comprehensive prof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092925ff9c44c9a3698d37a691543824
https://escholarship.org/uc/item/1qs671x0
https://escholarship.org/uc/item/1qs671x0
Publikováno v:
Annals of Neurology. 83:13-26
Monoclonal antibodies that target CD20 expressing B cells represent an important new treatment option for patients with multiple sclerosis (MS). B-cell-depleting therapy is highly effective against relapsing forms of the disease and is also the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3201f34531abcfea5f01c70859ad26de
https://doi.org/10.1002/ana.25119
https://doi.org/10.1002/ana.25119
Autor:
Klaus Lehmann-Horn, Jeffrey M. Gelfand, Sophia Michael, Sarosh R. Irani, Gildas Lepennetier, Sheng-zhi Wang, Arumugam Palanichamy, Michael D. Geschwind, Michael R. Wilson, H.-Christian von Büdingen, Ravi Dandekar, Ariele L. Greenfield, Scott S. Zamvil, Sarah Jahn
Publikováno v:
Neurology(R) neuroimmunology & neuroinflammation, vol 7, iss 2
Neurology® Neuroimmunology & Neuroinflammation
Neurology® Neuroimmunology & Neuroinflammation
ObjectiveTo study intrathecal B-cell activity in leucine-rich, glioma-inactivated 1 (LGI1) antibody encephalitis. In patients with LGI1 antibodies, the lack of CSF lymphocytosis or oligoclonal bands and serum-predominant LGI1 antibodies suggests a pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da36ded61753fa29a2b72e4ccbd32f9
https://mediatum.ub.tum.de/1609704
https://mediatum.ub.tum.de/1609704
Autor:
Keith Van Haren, Christopher P. Hess, Ariele L. Greenfield, Matthew J. Barkovich, Jeffrey M. Gelfand, Bryce A. Mendelsohn, Gabriel N. Mannis
Publikováno v:
Brain : a journal of neurology. 143(2)
Adult-onset leukoencephalopathy with spheroids and pigmented glia (ALSP) is an autosomal dominant leukoencephalopathy caused by mutations in colony stimulating factor 1 receptor (CSF1R). Here we report clinical and imaging outcomes following allogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176431b20d46e26b883b4285c685dab4
https://pubmed.ncbi.nlm.nih.gov/31840744
https://pubmed.ncbi.nlm.nih.gov/31840744
Publikováno v:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 16(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bb4c032b3fc9789a1d7394539d71b4
https://pubmed.ncbi.nlm.nih.gov/31087242
https://pubmed.ncbi.nlm.nih.gov/31087242
Autor:
Martin S. Weber, William Harkin, Natalie S. Pierson, Hao Wu, Ariele L. Greenfield, Ravi Dandekar, Michael R. Wilson, Stephen L. Hauser, H.-Christian von Büdingen, Sarah Laurent, Bruce A.C. Cree, Antje Bischof, Erica L. Eggers, Akshaya Ramesh, Roland G. Henry
B-cells are key contributors to chronic autoimmune pathology in multiple sclerosis (MS). Clonally related B-cells exist in the cerebrospinal fluid (CSF), meninges, and central nervous system (CNS) parenchyma of MS patients. Longitudinally stable CSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96ffc73d8d1bc98f6a0672c9f439a10
Autor:
David D. McKemy, Jonah R. Chan, Sarah Jahn, H.-Christian von Büdingen, Feng Mei, Yun-An A Shen, Hugh H. Reid, Ariele L. Greenfield
Publikováno v:
The Journal of Cell Biology
Chan, Jonah; von, H-C; Mei, F; Greenfield, A; Jahn, S; Shen, Y-AA; et al.(2015). The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9td8q9wz
Chan, Jonah; von, H-C; Mei, F; Greenfield, A; Jahn, S; Shen, Y-AA; et al.(2015). The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9td8q9wz
Myelin oligodendrocyte glycoprotein, expressed on the outermost lamellae of the myelin sheath, is a novel and specific binding partner for NGF that may modulate local concentrations of the neurotrophin in the spinal cord microenvironment.
Myelin
Myelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbce52cff4c5689a29c571e8862915c0
http://europepmc.org/articles/PMC4576870
http://europepmc.org/articles/PMC4576870
Autor:
Max Kazer, Michael R. Wilson, Natalie S. Pierson, Stanislas Demuth, H.-Christian von Büdingen, Aya Abounasr, Stephen L. Hauser, Roland G. Henry, Brady Michel, Hao Wu, Carolyn Bevan, Erica L. Eggers, Ariele L. Greenfield, Sheng-zhi Wang, Bruce A.C. Cree, Elizabeth G. Leitner, Antje Bischof
Publikováno v:
JCI insight, vol 2, iss 22
A role of B cells in multiple sclerosis (MS) is well established, but there is limited understanding of their involvement during active disease. Here, we examined cerebrospinal fluid (CSF) and peripheral blood (PB) B cells in treatment-naive patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c69cff79b3246855f12ab8f94b1de3
https://escholarship.org/uc/item/62h2h91b
https://escholarship.org/uc/item/62h2h91b