Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ariel Quiñones"'
Autor:
Yong-Jiang Cao, Ariel Quiñones, Christof M. Kramm, Nikolai G. Rainov, Karl-Ulrich Dobberstein, Constanze Nafe
Publikováno v:
Life Sciences. 73:1847-1860
Recombinant retroviruses (RV) have been widely used as vectors for clinical gene therapy of malignant brain tumors. Because of the very limited stability of these vectors in vivo, RV producing cells (VPC) are routinely used for intratumoral RV releas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636a847321faecbebc9a3bc5079b9e8c
https://doi.org/10.1016/s0024-3205(03)00542-3
https://doi.org/10.1016/s0024-3205(03)00542-3
Publikováno v:
Life Sciences. 72:2975-2992
The human egr - 1 gene encodes a zinc finger transcription factor induced by endogenous and exogenous stimuli such as growth factors, cytokines, and mitogens. Egr - 1 regulates other genes involved in growth and differentiation. The present study inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77a8ab973926031d73571ee44531851
https://doi.org/10.1016/s0024-3205(03)00230-3
https://doi.org/10.1016/s0024-3205(03)00230-3
Autor:
Nikolai G. Rainov, Ariel Quiñones
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 494:73-85
The tumor suppressor protein p53 is induced upon DNA damage essentially by post-translational regulatory mechanisms, which lead to a substantial increase of p53 levels. To exploit this essential property of p53, we developed a novel reporter system f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9a62ffa6dcd2c0c42b71ffe799ea46
https://doi.org/10.1016/s1383-5718(01)00179-6
https://doi.org/10.1016/s1383-5718(01)00179-6
Autor:
Xandra O. Breakefield, Ariel Quiñones, Miguel Sena-Esteves, Cornel Fraefel, Ulrich Herrlinger, Alice K. Jacobs, C. Woiciechowsky, Nikolai G. Rainov
Publikováno v:
Human Gene Therapy. 11:1429-1438
Subcutaneous vaccination therapy with glioma cells, which are retrovirally transduced to secrete granulocyte-macrophage colony-stimulating factor (GM-CSF), has previously proven effective in C57BL/6 mice harboring intracerebral GL261 gliomas. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1fb89467e42d6af6db1dd7d183d91d
https://doi.org/10.1089/10430340050057503
https://doi.org/10.1089/10430340050057503
Autor:
Ariel Quiñones, Susanne Neumann
Publikováno v:
Molecular Microbiology. 25:237-246
Mutations in the dnaQ gene, which encodes the proofreading epsilon-subunit of the DNA polymerase III holoenzyme, lead to a mutator phenotype caused by enhanced error rates during DNA replication. In this paper, we studied the influence of ssb mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8f49f828d648ee83d0abd7e5268752
https://doi.org/10.1046/j.1365-2958.1997.4531718.x
https://doi.org/10.1046/j.1365-2958.1997.4531718.x
Publikováno v:
ResearcherID
The polA gene of Escherichia coli encodes DNA polymerase I that is involved in DNA replication and repair. Despite the wide knowledge about structure and function of DNA polymerase I, there is little insight into the regulatory mechanisms involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d958b5943a333234cf5811165b69cf0b
https://doi.org/10.1046/j.1365-2958.1997.2961658.x
https://doi.org/10.1046/j.1365-2958.1997.2961658.x
Autor:
Ariel Quiñones, Sabine Kleinsteuber
Publikováno v:
Molecular and General Genetics MGG. 248:695-702
The replicative DNA helicase encoded by thednaB gene is essential for chromosomal DNA replication inEscherichia coli. The DnaB protein is a component of the σX-type primosome which is regarded as a model system for lagging strand synthesis of the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1f0b920fad4c44aff3050a605c5c0b
https://doi.org/10.1007/bf02191709
https://doi.org/10.1007/bf02191709
Publikováno v:
Biotechnology Letters. 22:383-385
An easy and cost-effective method for transport of living cell cultures which avoids the use of dry ice and prevents bacterial contamination is described. Cells are suspended in buffered culture medium in sealed and insulated 2 ml cryovials and are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f224825ce5c8f25e2b89c00d1164526e
https://doi.org/10.1023/a:1005624718463
https://doi.org/10.1023/a:1005624718463
Autor:
Carsten Milkowski, Ariel Quiñones
Publikováno v:
Current Microbiology. 23:333-336
DNA fragments fromSynechocystis sp. PCC 6803, which act as promoters inE. coli, were cloned by transcriptional gene fusion togalK. They were characterized by determining their relative strength. Shot-gun cloning ofSynechocystis DNA fragments resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07d88dfe3b3c96287296bbb06aee9d67
https://doi.org/10.1007/bf02104135
https://doi.org/10.1007/bf02104135
Publikováno v:
Molecular and General Genetics MGG. 231:81-87
The initiation protein DnaA of Escherichia coli regulates its own expression autogenously by binding to a 9 bp consensus sequence, the dnaA box, between the promoters dnaAP1 and dnaAP2. In this study, we analysed dnaA regulation in relation to DNA da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caf4644550b61f1f93716563f90890d
https://doi.org/10.1007/bf00293825
https://doi.org/10.1007/bf00293825