Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ariel M. Ley"'
Autor:
William D. Figg, Cindy H. Chau, Douglas K. Price, Walter Jager, Ji Luo, Maria Merino, Wooin Lee, Stefan Brenner, David J. Venzon, Nilay Thakkar, Jordan Smith, Phoebe Huang, Elena Fernandez, Tessa Campbell, Sarah Troutman, Kelie Reece, Jennifer van Velkinburgh, Suneet Shukla, Cody J. Peer, Shaunna Beedie, Edel M. McCrea, Jonathan D. Strope, Ariel M. Ley, Tristan M. Sissung
S3. t-SLCO1B3 expression was optimized using various concentrations of chetomin at different timepoints in (A) LNCaP and (B) 22Rv1 cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fab1d8efd7f5291e7200ddcb7ac8e7f
https://doi.org/10.1158/1541-7786.22511110
https://doi.org/10.1158/1541-7786.22511110
Autor:
William D. Figg, Cindy H. Chau, Douglas K. Price, Walter Jager, Ji Luo, Maria Merino, Wooin Lee, Stefan Brenner, David J. Venzon, Nilay Thakkar, Jordan Smith, Phoebe Huang, Elena Fernandez, Tessa Campbell, Sarah Troutman, Kelie Reece, Jennifer van Velkinburgh, Suneet Shukla, Cody J. Peer, Shaunna Beedie, Edel M. McCrea, Jonathan D. Strope, Ariel M. Ley, Tristan M. Sissung
Supplemental Figure Legends 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d4d5abd96307684690aa72019ffbb7
https://doi.org/10.1158/1541-7786.22511104
https://doi.org/10.1158/1541-7786.22511104
Autor:
William D. Figg, Cindy H. Chau, Douglas K. Price, Walter Jager, Ji Luo, Maria Merino, Wooin Lee, Stefan Brenner, David J. Venzon, Nilay Thakkar, Jordan Smith, Phoebe Huang, Elena Fernandez, Tessa Campbell, Sarah Troutman, Kelie Reece, Jennifer van Velkinburgh, Suneet Shukla, Cody J. Peer, Shaunna Beedie, Edel M. McCrea, Jonathan D. Strope, Ariel M. Ley, Tristan M. Sissung
Supplemental Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd7288bf1b67bdee1f96fc0c0453329
https://doi.org/10.1158/1541-7786.22511101.v1
https://doi.org/10.1158/1541-7786.22511101.v1
Autor:
Cody J Peer, Jonathan D Strope, Shaunna Beedie, Ariel M Ley, Alesia Holly, Karim Calis, Ronald Farkas, Jagan Parepally, Angela Men, Emmanuel O Fadiran, Pamela Scott, Marjorie Jenkins, William H. Theodore, Tristan M Sissung
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Objectives: The recommended zolpidem starting dose was lowered in females (5mg vs 10mg) since side effects were more frequent and severe than those of males; the mechanism underlying sex differences in pharmacokinetics (PK) is unknown. We hypothesize
Externí odkaz:
https://doaj.org/article/f8a554d8cde240a2a198d4a29f9008b5
Autor:
Chester J Joyner, Ariel M Ley, Doan C Nguyen, Mohammad Ali, Alessia Corrado, Christopher Tipton, Christopher D Scharer, Tian Mi, Matthew C Woodruff, Jennifer Hom, Jeremy M Boss, Meixue Duan, Greg Gibson, Danielle Roberts, Joel Andrews, Sagar Lonial, Inaki Sanz, F Eun-Hyung Lee
Publikováno v:
Life Science Alliance
This study shows that the generation of human long-lived plasma cells requires blood antibody secreting cells to undergo epigenetic and transcriptional reprogramming in response to the bone marrow microniche to become apoptosis resistant and survive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77bb114743c0d0e8c2c737a5bb63ed00
https://pubmed.ncbi.nlm.nih.gov/34952892
https://pubmed.ncbi.nlm.nih.gov/34952892
Autor:
Matthew C. Woodruff, Richard P. Ramonell, Kevin S. Cashman, Doan C. Nguyen, Ankur Singh Saini, Natalie Haddad, Ariel M. Ley, Shuya Kyu, J. Christina Howell, Tugba Ozturk, Saeyun Lee, Weirong Chen, Jacob Estrada, Andrea Morrison-Porter, Andrew Derrico, Fabliha A. Anam, Monika Sharma, Henry Wu, Sang N. Le, Scott A. Jenks, Christopher M. Tipton, John L. Daiss, William T. Hu, F. Eun-Hyung Lee, Ignacio Sanz
Publikováno v:
Nat Immunol
Wide heterogeneity of disease course ranging from asymptomatic spread to respiratory failure and death has become a hallmark of the SARS-CoV-2 pandemic. While this clinical spectrum is well documented, its immunologic underpinnings are less clear. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3411ce9cc22f528f7cc3b1ab0dfeecb5
https://doi.org/10.1101/2020.04.29.20083717
https://doi.org/10.1101/2020.04.29.20083717
Autor:
Julie A. Hong, Edel M. McCrea, David S. Schrump, Patrick J. Grohar, Jonathan P. Jackson, David Venzon, Mary Zhang, Kenneth R. Brouwer, William D. Figg, Ralph J. Hauke, Cody J. Peer, Jon Glod, Theo Heller, Roberto H. Barbier, Jonathan D. Strope, Tristan M. Sissung, Brigitte C. Widemann, Phoebe A. Huang, Ariel M. Ley
Publikováno v:
Molecular pharmacology. 96(2)
Mithramycin demonstrates preclinical anticancer activity, but its therapeutic dose is limited by the development of hepatotoxicity that remains poorly characterized. A pharmacogenomics characterization of mithramycin-induced transaminitis revealed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143e630a530ce8dc585e067e0fc52f5d
https://pubmed.ncbi.nlm.nih.gov/31175181
https://pubmed.ncbi.nlm.nih.gov/31175181
Autor:
Kelie M. Reece, Tristan M. Sissung, Elena V. Fernandez, William D. Figg, Sarah M. Troutman, Ariel M. Ley, Douglas K. Price, Cindy H. Chau
Publikováno v:
Molecular Pharmacology. 87:1006-1012
Enzalutamide is a potent second-generation androgen receptor (AR) antagonist with activity in metastatic castrate-resistant prostate cancer (CRPC). Although enzalutamide is initially effective, disease progression inevitably ensues with the emergence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9979256708cf7f470fd10f537aa8f718
https://doi.org/10.1124/mol.114.097477
https://doi.org/10.1124/mol.114.097477
Autor:
Walter Jäger, Edel M. McCrea, Douglas K. Price, Tessa J Campbell, Sarah M. Troutman, Suneet Shukla, Jonathan D. Strope, Jordan L. Smith, Maria Merino, Wooin Lee, Kelie M. Reece, Cody J. Peer, Jennifer van Velkinburgh, William D. Figg, David Venzon, Stefan Brenner, Tristan M. Sissung, Phoebe A. Huang, Ji Luo, Cindy H. Chau, Ariel M. Ley, Nilay Thakkar, Elena V. Fernandez, Shaunna L. Beedie
Castration-resistant prostate cancer (CRPC) has greater intratumoral testosterone concentrations than similar tumors from eugonadal men; simple diffusion does not account for this observation. This study was undertaken to ascertain the androgen uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d430a784ebf29916c209debd48684c7f
https://europepmc.org/articles/PMC5540879/
https://europepmc.org/articles/PMC5540879/
Autor:
Tristan M. Sissung, Phoebe A. Huang, Ralph Hauke, Edel McCrea, Cody J. Peer, Roberto H. Barbier, Jonathan D. Strope, Ariel M. Ley, Mary Zhang, Julie A. Hong, David Venzon, Jonathan P. Jackson, Kenneth R. Brouwer, Patrick Grohar, John Glod, Brigitte C. Widemann, Theo Heller, David S. Schrump, William D. Figg
Publikováno v:
Cancer Research. 79:2943-2943
Mithramycin has shown significant preclinical anticancer activity, but its therapeutic dose is limited by the development of hepatotoxicity that remains poorly characterized. A pharmacogenomics characterization of mithramycin-induced transaminitis re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7d58b1c6c4779f9d958eef8208c0e62
https://doi.org/10.1158/1538-7445.am2019-2943
https://doi.org/10.1158/1538-7445.am2019-2943