Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ariel L. Hernandez"'
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Supplementary Figure S2 demonstrates the enrichment of Fanoni Anemia pathway genes as a function of SMAD4 levels (in TCGA analyses)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e110d7f7829493e6c8760bade2e2d37
https://doi.org/10.1158/1078-0432.22473941
https://doi.org/10.1158/1078-0432.22473941
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Supplementary Figure S3 demonstrates doxycyline-dependent modulation of SMAD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a04afb3e7567e457967c7b3c714ab51
https://doi.org/10.1158/1078-0432.22473938.v1
https://doi.org/10.1158/1078-0432.22473938.v1
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Supplementary Figure S5 demonstrates the influence of SMAD4 status on proliferation (with and without treatment)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155adeab792dae8c4e149922d01eeedd
https://doi.org/10.1158/1078-0432.22473932.v1
https://doi.org/10.1158/1078-0432.22473932.v1
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Supplementary Figure S6 demonstrates the influence of SMAD4 status on DNA damage response to RT + olaparib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6916ce80b7d1c3dc08d01d58b34f8161
https://doi.org/10.1158/1078-0432.22473929
https://doi.org/10.1158/1078-0432.22473929
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Purpose:SMAD4 loss causes genomic instability and the initiation/progression of head and neck squamous cell carcinoma (HNSCC). Here, we study whether SMAD4 loss sensitizes HNSCCs to olaparib (PARP inhibitor) in combination with radiotherapy (RT).Expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed57d87b4dc307e59b1af2c8407acc17
https://doi.org/10.1158/1078-0432.c.6528641.v1
https://doi.org/10.1158/1078-0432.c.6528641.v1
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Supplementary Table S1 lists reagents used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea4451604ade363daac70ce019cc408
https://doi.org/10.1158/1078-0432.22473926
https://doi.org/10.1158/1078-0432.22473926
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Supplementary Figure S4 demonstrates the influence of SMAD4 expression in CAL27 xenograft growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba01604bffdac95fd92182197fd1f6f7
https://doi.org/10.1158/1078-0432.22473935
https://doi.org/10.1158/1078-0432.22473935
Autor:
Xiao-Jing Wang, David Raben, Sana D. Karam, Ayman J. Oweida, Kenneth L. Jones, Michael C. Rudolph, G. Devon Trahan, Guanting He, Gangwen Han, Barbara Frederick, Kyle Nolan, Kelsey Weigel, Li Bian, Christian D. Young, Ariel L. Hernandez
Supplementary Figure S1 demonstrates the correlation between SMAD4 levels and FANC/BRCA family genes (in TCGA analyses)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa2d55f45ecbabe45feeba25e5c79c3
https://doi.org/10.1158/1078-0432.22473944.v1
https://doi.org/10.1158/1078-0432.22473944.v1
Publikováno v:
Molecular Carcinogenesis. 58:1648-1655
SMAD4 is a potent tumor suppressor and a central mediator of the TGFß signaling pathway. SMAD4 genetic loss is frequent in squamous cell carcinomas (SCCs). Reports of SMAD4 expression in SCCs vary significantly possibly due to inter-tumor heterogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ebe9d8446ee760b8718a96c24091cb
https://doi.org/10.1002/mc.23049
https://doi.org/10.1002/mc.23049
Autor:
Michael C. Rudolph, Ayman Oweida, David Raben, Kelsey J. Weigel, Xiao-Jing Wang, Ariel L. Hernandez, Kyle Nolan, Li Bian, Christian D. Young, Kenneth L. Jones, Gangwen Han, Sana D. Karam, G Devon Trahan, Guanting He, Barbara Frederick
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 26, iss 12
Clin Cancer Res
Clin Cancer Res
Purpose: SMAD4 loss causes genomic instability and the initiation/progression of head and neck squamous cell carcinoma (HNSCC). Here, we study whether SMAD4 loss sensitizes HNSCCs to olaparib (PARP inhibitor) in combination with radiotherapy (RT). Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673ab1cd1985aeb4201ec77fd430e82d
https://escholarship.org/uc/item/1h71b30c
https://escholarship.org/uc/item/1h71b30c