The Candida auris Hog1 MAP kinase is essential for the colonization of murine skin and intradermal persistence

Autor: Raju Shivarathri, Manju Chauhan, Abhishek Datta, Diprasom Das, Adela Karuli, Ariel Aptekmann, Sabrina Jenull, Karl Kuchler, Shankar Thangamani, Anuradha Chowdhary, Jigar V. Desai, Neeraj Chauhan

Publikováno v: mBio, Vol 15, Iss 11 (2024)

ABSTRACT Candida auris, a multidrug-resistant human fungal pathogen, was first identified in 2009 in Japan. Since then, systemic C. auris infections have now been reported in more than 50 countries, with mortality rates of 30%–60%. A major contribu

Externí odkaz: https://doaj.org/article/7431887bf42b42859583285cb299ad9f

Transcriptomic analysis and molecular docking reveal genes involved in the response of Aedes aegypti larvae to an essential oil extracted from Eucalyptus.

Autor: Ivana Sierra, Jose Manuel Latorre-Estivalis, Lucila Traverso, Paula V Gonzalez, Ariel Aptekmann, Alejandro Daniel Nadra, Héctor Masuh, Sheila Ons

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009587 (2021)

BackgroundAedes aegypti (L.) is an urban mosquito, vector of several arboviruses that cause severe diseases in hundreds of million people each year. The resistance to synthetic insecticides developed by Ae. aegypti populations worldwide has contribut

Externí odkaz: https://doaj.org/article/b970bd6e08fe408fba45eade6788ec87

Computational Approaches for Unraveling the Effects of Variation in the Human Genome and Microbiome

Autor: Yanran Wang, Chengsheng Zhu, Zishuo Zeng, Yannick Mahlich, Maximilian Miller, Yana Bromberg, Ariel Aptekmann

Publikováno v: Annual Review of Biomedical Data Science. 3:411-432

The past two decades of analytical efforts have highlighted how much more remains to be learned about the human genome and, particularly, its complex involvement in promoting disease development and progression. While numerous computational tools exi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0329783798e398e2bda650faa6cbb24c
https://doi.org/10.1146/annurev-biodatasci-030320-041014

Transcriptomic analysis and molecular docking reveal genes involved in the response of Aedes aegypti larvae to an essential oil extracted from Eucalyptus

Autor: Lucila Traverso, Ivana Sierra, Sheila Ons, Hector Mario Masuh, Paula Valeria Gonzalez, Ariel Aptekmann, Alejandro D. Nadra, Jose Manuel Latorre-Estivalis

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 7, p e0009587 (2021)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
PLoS Neglected Tropical Diseases

Background: Aedes aegypti (L.) is an urban mosquito, vector of several arboviruses that cause severe diseases in hundreds of million people each year. The resistance to synthetic insecticides developed by Ae. aegypti populations worldwide has contrib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4960b06f9214fe3c466b76a5c1617197
http://sedici.unlp.edu.ar/handle/10915/145515

Thousands of protein linear motif classes may still be undiscovered

Autor: Denys Bulavka, Ariel Aptekmann, Nicolás A Méndez, Teresa Krick, Ignacio E. Sánchez

Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0248841 (2021)
PLoS ONE

Linear motifs are short protein subsequences that mediate protein interactions. Hundreds of motif classes including thousands of motif instances are known. Our theory estimates how many motif classes remain undiscovered. As commonly done, we describe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5036cc0b614e56082b2a1fdbf2cf326
https://doaj.org/article/10db20a6df4e442dab7d8b3d3ee26975