Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Ariel Andrew"'
1
Akademický článek
Aurora B inhibition induces hyper-polyploidy and loss of long-term proliferative potential in RB and p53 defective cells
Autor: Shivam Vora, Saptarshi Chatterjee, Ariel Andrew, Ramyashree Prasanna Kumar, Martina Proctor, Zhen Zeng, Rituparna Bhatt, Deborah Nazareth, Madushan Fernando, Mathew J. K. Jones, Yaowu He, John D. Hooper, Nigel A. J. McMillan, Jelena Urosevic, Jamal Saeh, Jon Travers, Daniela Cimini, Jing Chen, Brian Gabrielli
Publikováno v: Cell Death and Disease, Vol 16, Iss 1, Pp 1-11 (2025)
Abstract Polyploidy is a common outcome of chemotherapies, but there is conflicting evidence as to whether polyploidy is an adverse, benign or even favourable outcome. We show Aurora B kinase inhibitors efficiently promote polyploidy in many cell typ
Externí odkaz: https://doaj.org/article/4cd9fc9bb00a432f88e8885822f16094
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2
Akademický článek
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition
Autor: Shivam Vora, Ariel Andrew, Ramyashree Prasanna Kumar, Deborah Nazareth, Alexis Bonfim-Melo, Yoon Lim, Xin Yee Ong, Madushan Fernando, Yaowu He, John D. Hooper, Nigel AJ McMillan, Jelena Urosevic, Jon Travers, Jamal Saeh, Sharad Kumar, Mathew JK Jones, Brian Gabrielli
Publikováno v: Cell Death and Disease, Vol 15, Iss 11, Pp 1-9 (2024)
Abstract Aurora B kinase (AURKB) inhibitors have been trialled in a range of different tumour types but are not approved for any indication. Expression of the human papilloma virus (HPV) oncogenes and loss of retinoblastoma (RB) protein function has
Externí odkaz: https://doaj.org/article/3d015f58b83e447f8885ff4062e043e7
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4
A Personal Note: Contemporary American Power Dynamics and John Steinbeck's Nonfiction
Autor: Ariel Andrew
Publikováno v: Steinbeck Review. 15:56-61
The author connects John Steinbeck's sociopolitical commentary from newspaper articles and columns to contemporary social issues, such as racism, xenophobia, and nationalism.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f247d239b2555fe18e87c7ca9bf36e8
https://doi.org/10.5325/steinbeckreview.15.1.0056
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