Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Ariel Amir"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract A critical cell cycle checkpoint for most bacteria is the onset of constriction when the septal peptidoglycan synthesis starts. According to the current understanding, the arrival of FtsN to midcell triggers this checkpoint in Escherichia co
Externí odkaz:
https://doaj.org/article/5889565a30e44d489ce36be2da79686b
Publikováno v:
Communications Psychology, Vol 2, Iss 1, Pp 1-18 (2024)
Abstract Surging interest in individual differences has faced setbacks in light of recent replication crises in psychology, for example in brain-wide association studies exploring brain-behavior correlations. A crucial component of replicability for
Externí odkaz:
https://doaj.org/article/6113ecd548b34bd699192f522c40c4ad
Publikováno v:
eLife, Vol 12 (2024)
The adaptive dynamics of evolving microbial populations takes place on a complex fitness landscape generated by epistatic interactions. The population generically consists of multiple competing strains, a phenomenon known as clonal interference. Micr
Externí odkaz:
https://doaj.org/article/15b2ca3098e34cb080e9a580a95ba2f1
Autor:
Nadia Vertti-Quintero, Ethan Levien, Lucie Poggi, Ariel Amir, Guy-Franck Richard, Charles N. Baroud
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Double-strand break repair (DSBR) is a highly regulated process involving dozens of proteins acting in a defined order to repair a DNA lesion that is fatal for any living cell. Model organisms such as Saccharomyces cerevisiae have
Externí odkaz:
https://doaj.org/article/cc8a768518374721880ab711674c5086
Autor:
Yipei Guo, Ariel Amir
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Maintaining protein expression levels is essential to cellular homeostasis. Here, the authors investigate how transcription factors affect the stability of protein expression in a gene regulatory network, and highlight the importance of network topol
Externí odkaz:
https://doaj.org/article/8344d6f0b14f47efb0ad50b8889fd622
Publikováno v:
Cell Reports, Vol 38, Iss 12, Pp 110539- (2022)
Summary: Escherichia coli cell cycle features two critical cell-cycle checkpoints: initiation of replication and the onset of constriction. While the initiation of DNA replication has been extensively studied, it is less clear what triggers the onset
Externí odkaz:
https://doaj.org/article/5881fdfd149946d6bb362b30378cf1db
Publikováno v:
eLife, Vol 10 (2021)
Collection of high-throughput data has become prevalent in biology. Large datasets allow the use of statistical constructs such as binning and linear regression to quantify relationships between variables and hypothesize underlying biological mechani
Externí odkaz:
https://doaj.org/article/3c380e98d2284926958eea57a7ad7af5
Autor:
Felix Wong, Sean Wilson, Ralf Helbig, Smitha Hegde, Olha Aftenieva, Hai Zheng, Chenli Liu, Teuta Pilizota, Ethan C. Garner, Ariel Amir, Lars D. Renner
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Mechanical rupture, or lysis, of the cytoplasmic membrane is a common cell death pathway in bacteria occurring in response to β-lactam antibiotics. A better understanding of the cellular design principles governing the susceptibility and response of
Externí odkaz:
https://doaj.org/article/17832b622a5c4604841350be642fec93
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1009080 (2021)
Microbial populations show striking diversity in cell growth morphology and lifecycle; however, our understanding of how these factors influence the growth rate of cell populations remains limited. We use theory and simulations to predict the impact
Externí odkaz:
https://doaj.org/article/b3e7d352ccfe4e518b0c526e350510e7
Publikováno v:
eLife, Vol 9 (2020)
In biological contexts as diverse as development, apoptosis, and synthetic microbial consortia, collections of cells or subcellular components have been shown to overcome the slow signaling speed of simple diffusion by utilizing diffusive relays, in
Externí odkaz:
https://doaj.org/article/80cdc21c72114c1bbeb37093f6b82b89