Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ariel, Jaitovich"'
Autor:
Joseph Balnis, Andy Madrid, Lisa A. Drake, Rachel Vancavage, Anupama Tiwari, Vraj J. Patel, Ramon Bossardi Ramos, John J. Schwarz, Recai Yucel, Harold A. Singer, Reid S. Alisch, Ariel Jaitovich
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105251- (2024)
Summary: Background: DNA methylation integrates environmental signals with transcriptional programs. COVID-19 infection induces changes in the host methylome. While post-acute sequelae of COVID-19 (PASC) is a long-term complication of acute illness,
Externí odkaz:
https://doaj.org/article/fbb65d32c5c74a52a39bd435d43f1d81
Autor:
Mats W. Johansson, Joseph Balnis, Laura K. Muehlbauer, Yury V. Bukhman, Matthew S. Stefely, Katherine A. Overmyer, Rachel Vancavage, Anupama Tiwari, Anish Raj Adhikari, Paul J. Feustel, Bradford S. Schwartz, Joshua J. Coon, Ron Stewart, Ariel Jaitovich, Deane F. Mosher
Publikováno v:
Physiological Reports, Vol 11, Iss 17, Pp n/a-n/a (2023)
Abstract Cartilage acidic protein‐1 (CRTAC1) is produced by several cell types, including Type 2 alveolar epithelial (T2AE) cells that are targeted by SARS‐CoV2. Plasma CRTAC1 is known based on proteomic surveys to be low in patients with severe
Externí odkaz:
https://doaj.org/article/c1f11d90a5054294aa369231a2511ab9
Autor:
Clinton Mathai, Frances Jourd'heuil, Le Gia Cat Pham, Kurrim Gilliard, Dennis Howard, Joseph Balnis, Ariel Jaitovich, Sridar V. Chittur, Mark Rilley, Ruben Peredo-Wende, Ibrahim Ammoura, Sandra J. Shin, Margarida Barroso, Jonathan Barra, Evgenia Shishkova, Joshua J. Coon, Reynold I. Lopez-Soler, David Jourd'heuil
Publikováno v:
Redox Biology, Vol 65, Iss , Pp 102838- (2023)
Identifying novel regulators of vascular smooth muscle cell function is necessary to further understand cardiovascular diseases. We previously identified cytoglobin, a hemoglobin homolog, with myogenic and cytoprotective roles in the vasculature. The
Externí odkaz:
https://doaj.org/article/e2ea6201c6364609aa8d71c26b37331d
Autor:
Ariel Jaitovich, Camille L. Dumas, Ria Itty, Hau C. Chieng, Malik M. H. S. Khan, Ali Naqvi, John Fantauzzi, Jesse B. Hall, Paul J. Feustel, Marc A. Judson
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Abstract Background Reduced body weight at the time of intensive care unit (ICU) admission is associated with worse survival, and a paradoxical benefit of obesity has been suggested in critical illness. However, no research has addressed the survival
Externí odkaz:
https://doaj.org/article/6f47c9309a19415dba0997c1b5cf8676
Publikováno v:
Respiratory Medicine Case Reports, Vol 40, Iss , Pp 101770- (2022)
Lymphomatoid granulomatosis (LG) is an extremely rare disease and is an unusual cause of central airway obstruction (CAO) with no standard of treatment in these conditions. LG is characterized by angioinvasion and angioinfiltration along with lymphoh
Externí odkaz:
https://doaj.org/article/26701e9cf1ac444a9d05c3d9da01cb43
Autor:
Nina Martino, Ramon Bossardi Ramos, Shuhan Lu, Kara Leyden, Lindsay Tomaszek, Sudeshna Sadhu, Gabrielle Fredman, Ariel Jaitovich, Peter A. Vincent, Alejandro P. Adam
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
SOCS3 is the main inhibitor of the JAK/STAT3 pathway. This pathway is activated by interleukin 6 (IL-6), a major mediator of the cytokine storm during shock. To determine its role in the vascular response to shock, we challenged mice lacking SOCS3 in
Externí odkaz:
https://doaj.org/article/0c99c2c81bfe447998ea6d2bf13bcda6
Autor:
Brenda M. Juan Guardela, Jiehuan Sun, Tong Zhang, Bing Xu, Joseph Balnis, Yong Huang, Shwu-Fan Ma, Philip L. Molyneaux, Toby M. Maher, Imre Noth, Gaetane Michaud, Ariel Jaitovich, Jose D. Herazo-Maya
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103439- (2021)
Background: COVID-19 has been associated with Interstitial Lung Disease features. The immune transcriptomic overlap between Idiopathic Pulmonary Fibrosis (IPF) and COVID-19 has not been investigated. Methods: we analyzed blood transcript levels of 50
Externí odkaz:
https://doaj.org/article/07fb319554534d859f4e0ebafcab419c
Autor:
Joseph Balnis, Andy Madrid, Kirk J. Hogan, Lisa A. Drake, Anish Adhikari, Rachel Vancavage, Harold A. Singer, Reid S. Alisch, Ariel Jaitovich
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:594-597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdf2a0cb3f19600d1ca07fc9611a703c
https://doi.org/10.1165/rcmb.2022-0433le
https://doi.org/10.1165/rcmb.2022-0433le
Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States
Autor:
Lena F. Schimke, Alexandre H. C. Marques, Gabriela Crispim Baiocchi, Caroline Aliane de Souza Prado, Dennyson Leandro M. Fonseca, Paula Paccielli Freire, Desirée Rodrigues Plaça, Igor Salerno Filgueiras, Ranieri Coelho Salgado, Gabriel Jansen-Marques, Antonio Edson Rocha Oliveira, Jean Pierre Schatzmann Peron, Gustavo Cabral-Miranda, José Alexandre Marzagão Barbuto, Niels Olsen Saraiva Camara, Vera Lúcia Garcia Calich, Hans D. Ochs, Antonio Condino-Neto, Katherine A. Overmyer, Joshua J. Coon, Joseph Balnis, Ariel Jaitovich, Jonas Schulte-Schrepping, Thomas Ulas, Joachim L. Schultze, Helder I. Nakaya, Igor Jurisica, Otávio Cabral-Marques
Publikováno v:
Cells, Vol 11, Iss 5, p 847 (2022)
Severe COVID-19 patients present a clinical and laboratory overlap with other hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH). However, the underlying mechanisms of these conditions remain to be explored. Here, we invest
Externí odkaz:
https://doaj.org/article/5d38a95098184123904d7717c0fac886
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Patients with chronic pulmonary conditions such as chronic obstructive pulmonary disease (COPD) often develop skeletal muscle dysfunction, which is strongly and independently associated with poor outcomes including higher mortality. Some of these pat
Externí odkaz:
https://doaj.org/article/781be54b889940449bc56de5b9b62fd8