Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Arie J. Hoogendijk"'
Autor:
Panagiota Bouti, Bart J. A. M. Klein, Paul J. H. Verkuijlen, Karin Schornagel, Floris P. J. van Alphen, Kees-Karel H. Taris, Maartje van den Biggelaar, Arie J. Hoogendijk, Robin van Bruggen, Taco W. Kuijpers, Hanke L. Matlung
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe importance of CD11b/CD18 expression in neutrophil effector functions is well known. Beyond KINDLIN3 and TALIN1, which are involved in the induction of the high-affinity binding CD11b/CD18 conformation, the signaling pathways that orches
Externí odkaz:
https://doaj.org/article/53bd94c6190c4bc09c41a6251de19372
Autor:
Marthe Minderman, Hildo Lantermans, Carmen van der Zwaan, Arie J. Hoogendijk, Maartje van den Biggelaar, Marie José Kersten, Marcel Spaargaren, Steven T. Pals
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract MYD88 is the key signaling adaptor-protein for Toll-like and interleukin-1 receptors. A somatic L265P mutation within the Toll/interleukin-1 receptor (TIR) domain of MYD88 is found in 90% of Waldenström macroglobulinemia cases and in a sign
Externí odkaz:
https://doaj.org/article/6567367aa7a8454c9dcdd166992c7d1a
Autor:
Stijn A. Groten, Eva R. Smit, Esmée F. J. Janssen, Bart L. van den Eshof, Floris P. J. van Alphen, Carmen van der Zwaan, Alexander B. Meijer, Arie J. Hoogendijk, Maartje van den Biggelaar
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Vascular endothelial cells (ECs) form a dynamic interface between blood and tissue and play a crucial role in the progression of vascular inflammation. Here, we aim to dissect the system-wide molecular mechanisms of inflammatory endothelial-
Externí odkaz:
https://doaj.org/article/14e6d1dfbe254a5bb29f4f4bd6c78adf
Autor:
Marije Kat, Ellie Karampini, Arie J. Hoogendijk, Petra E. Bürgisser, Aat A. Mulder, Floris P.J. van Alphen, Jenny Olins, Dirk Geerts, Maartje van den Biggelaar, Coert Margadant, Jan Voorberg, Ruben Bierings
Publikováno v:
Haematologica, Vol 107, Iss 8 (2022)
Von Willebrand factor (VWF) is a multimeric hemostatic protein primarily synthesized in endothelial cells. VWF is stored in endothelial storage organelles, the Weibel-Palade bodies (WPB), whose biogenesis strongly depends on VWF anterograde trafficki
Externí odkaz:
https://doaj.org/article/3f3b76fdbfd641bd82110fcb6a81d836
Autor:
Xanthe Brands, Fabrice Uhel, Lonneke A. van Vught, Maryse A. Wiewel, Arie J. Hoogendijk, René Lutter, Marcus J. Schultz, Brendon P. Scicluna, Tom van der Poll
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
Objective Patients admitted to the Intensive Care Unit (ICU) oftentimes show immunological signs of immune suppression. Consequently, immune stimulatory agents have been proposed as an adjunctive therapy approach in the ICU. The objective of this stu
Externí odkaz:
https://doaj.org/article/766c335086a943f5bf7157edd701cb96
Autor:
Hina N. Khan, Xanthe Brands, Simona Aufiero, Arie J. Hoogendijk, Augustijn M. Klarenbeek, Tjitske S. R. van Engelen, Bastiaan W. Haak, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Tom van der Poll, Brendon P. Scicluna
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-12 (2020)
Abstract Background Dysregulation of the host immune response is a pathognomonic feature of sepsis. Abnormal physiological conditions are understood to shift efficient linear splicing of protein-coding RNA towards non-canonical splicing, characterize
Externí odkaz:
https://doaj.org/article/513972d7beef4ee78770d62e5c16ca46
Autor:
Laura R. A. Schouten, Lieuwe D. J. Bos, A. Serpa Neto, Lonneke A. van Vught, Maryse A. Wiewel, Arie J. Hoogendijk, Marc J. M. Bonten, Olaf L. Cremer, Janneke Horn, Tom van der Poll, Marcus J. Schultz, Roelie M. Wösten-van Asperen, the MARS consortium
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-20 (2019)
Abstract Background Advanced age is associated with increased mortality in acute respiratory distress syndrome (ARDS) patients. Preclinical studies suggest that the host response to an injurious challenge is age-dependent. In ARDS patients, we invest
Externí odkaz:
https://doaj.org/article/9465e16a3ed34082a8a00e9abe335311
Autor:
Niels van Mourik, MD, Bart F. Geerts, MD, PhD, MSc, MBA, Jan M. Binnekade, PhD, Denise P. Veelo, MD, PhD, Lieuwe D. J. Bos, , MD, PhD, MSc, W. Joost Wiersinga, MD, PhD, MBA, Tom van der Poll, MD, PhD, Olaf L. Cremer, MD, PhD, Marcus J. Schultz, MD, PhD, Alexander P. J. Vlaar, MD, PhD, MBA, on behalf of the MARS consortium, Laura R. A. Schouten, Lonneke A. van Vught, Maryse A. Wiewel, David S. Y. Ong, Jos F. Frencken, Marc Bonten, Peter M. C. Klein Klouwenberg, Roosmarijn T. M. van Hooijdonk, Mischa A. Huson, Marleen Straat, Esther Witteveen, Gerie J. Glas, Luuk Wieske, Brendon P. Scicluna, Hakima Belkasim-Bohoudi, Arie J. Hoogendijk
Publikováno v:
Critical Care Explorations, Vol 2, Iss 10, p e0219 (2020)
Objectives:. Previous studies demonstrated that extensive fluid loading and consequently positive fluid balances during sepsis resuscitation are associated with adverse outcome. Yet, the association between fluid balance and mortality after reversal
Externí odkaz:
https://doaj.org/article/3843ab0805e14a35b4799141cd2ef11e
Autor:
Małgorzata A. Przeradzka, Josse van Galen, Eduard H. T. M. Ebberink, Arie J. Hoogendijk, Carmen van der Zwaan, Koen Mertens, Maartje van den Biggelaar, Alexander B. Meijer
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
In the complex with von Willebrand factor (VWF) factor VIII (FVIII) is protected from rapid clearance from circulation. Although it has been established that the FVIII binding site resides in the N-terminal D’-D3 domains of VWF, detailed informatio
Externí odkaz:
https://doaj.org/article/98ca5b10a4244362b3d0ecc8995feea4
Autor:
Arie J. Hoogendijk, Farzin Pourfarzad, Cathelijn E.M. Aarts, Anton T.J. Tool, Ida H. Hiemstra, Luigi Grassi, Mattia Frontini, Alexander B. Meijer, Maartje van den Biggelaar, Taco W. Kuijpers
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2505-2519.e4 (2019)
Summary: Human neutrophilic granulocytes form the largest pool of innate immune cells for host defense against bacterial and fungal pathogens. The dynamic changes that accompany the metamorphosis from a proliferating myeloid progenitor cell in the bo
Externí odkaz:
https://doaj.org/article/468e8cb9603e435dbc1cebda5c7f95a3