Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Arie Abo"'
Autor:
Xiaoxian Zhao, Shweta Singh, Cecile Pardoux, Jingsong Zhao, Eric D. Hsi, Arie Abo, Wouter Korver
Publikováno v:
Haematologica, Vol 95, Iss 1 (2010)
Background C-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells. To validate the potential of this receptor as a therapeutic target in acute myeloid leukemia, we g
Externí odkaz:
https://doaj.org/article/52b9ee8f6f09436cb0587ec224e90bd9
Purpose: Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity. TF is highly expressed in human colorectal tumors, and levels are positively correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3216eda37e6fe0539472d760b5f7bf8e
https://doi.org/10.1158/1078-0432.c.6516891
https://doi.org/10.1158/1078-0432.c.6516891
Supplementary Data from rNAPc2 Inhibits Colorectal Cancer in Mice through Tissue Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33f5a9c44bbc57f757bb2bb6dd1f91f
https://doi.org/10.1158/1078-0432.22439421
https://doi.org/10.1158/1078-0432.22439421
Publikováno v:
Stem Cells Translational Medicine. 3:1393-1397
Summary Debilitating eye diseases such as age-related macular degeneration and retinitis pigmentosa currently represent a large unmet medical need that could potentially be addressed by stem cell therapy. A number of novel stem cell-based cellular th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9f9dc6ab309a1e99b9c594066c811b
https://doi.org/10.5966/sctm.2014-0221
https://doi.org/10.5966/sctm.2014-0221
Autor:
Minke E. Binnerts, Julia Luther, Alfiya Akhmetshina, Michael Stock, Kyung Ah Kim, Stefan Uderhardt, Cordula Surmann-Schmitt, Jessica M. Bright, Gerhard Krönke, Shahla Abdollahi-Roodsaz, Arie Abo, Georg Schett, Karolyn Tran, Leo A. B. Joosten, Mario M. Zaiss, Christina Böhm, Jean-Pierre David, Julia Katzenbeisser, Carina Scholtysek, Jörg H W Distler
Publikováno v:
Arthritis and Rheumatism, 62, 8, pp. 2303-12
Arthritis and Rheumatism, 62, 2303-12
Arthritis and Rheumatism, 62, 2303-12
Contains fulltext : 89535.pdf (Publisher’s version ) (Closed access) OBJECTIVE: During the course of different musculoskeletal diseases, joints are progressively damaged by inflammatory, infectious, or mechanical stressors, leading to joint destruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ff8493b661c93105b4c7f79bac4f39
https://hdl.handle.net/2066/89535
https://hdl.handle.net/2066/89535
Autor:
Esther Danenberg, Johan H. van Es, Pekka Kujala, Arie Abo, Daniel E. Stange, Maaike van den Born, Jeroen Korving, Hans Clevers, Nicholas A. Wright, Hugo J. Snippert, Nick Barker, Toshiro Sato, Harry Begthel, Meritxell Huch, Stieneke van den Brink, Marc van de Wetering, Richard Poulsom, Peter J. Peters
Publikováno v:
Cell Stem Cell, 6(1), 25-36. Cell Press
Cell Stem Cell
Cell Stem Cell; Vol 6
Cell Stem Cell
Cell Stem Cell; Vol 6
SummaryThe study of gastric epithelial homeostasis and cancer has been hampered by the lack of stem cell markers and in vitro culture methods. The Wnt target gene Lgr5 marks stem cells in the small intestine, colon, and hair follicle. Here, we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d1828e4b0777b2501287d30e95f8db
https://doi.org/10.1016/j.stem.2009.11.013
https://doi.org/10.1016/j.stem.2009.11.013
Autor:
Jingsong Zhao, Arie Abo, Wouter Korver, Xiaoxian Zhao, Cécile Pardoux, Shweta Singh, Eric D. Hsi
Publikováno v:
Haematologica. 95:71-78
Background C-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells. To validate the potential of this receptor as a therapeutic target in acute myeloid leukemia, we g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f976485af06ad985ca69eea29ee15e37
https://doi.org/10.3324/haematol.2009.009811
https://doi.org/10.3324/haematol.2009.009811
Publikováno v:
Proceedings of the National Academy of Sciences. 106:2331-2336
R-Spondin1 (RSpo1) is a novel secreted protein that augments canonical Wnt/β-catenin signaling. We injected recombinant RSpo1 protein into transgenic Wnt reporter TOPGAL mice and have identified the oral mucosa as a target tissue for RSpo1. Administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485d5b5658158d8ffe343d1b4d820e8a
https://doi.org/10.1073/pnas.0805159106
https://doi.org/10.1073/pnas.0805159106
Autor:
Marc van de Wetering, Robert G.J. Vries, Hans Clevers, Johan H. van Es, Arie Abo, Peter J. Peters, Nick Barker, Pekka Kujala, Toshiro Sato, Daniel E. Stange, Hugo J. Snippert
Publikováno v:
Nature, 459(7244), 262-265. Nature Publishing Group
The intestinal epithelium is the most rapidly self-renewing tissue in adult mammals. We have recently demonstrated the presence of about six cycling Lgr5(+) stem cells at the bottoms of small-intestinal crypts. Here we describe the establishment of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973185de1874d84d3bf4b8ebf81d219e
https://hdl.handle.net/20.500.11755/5e976e93-3fb9-4616-8f6b-a49c2fe283d8
https://hdl.handle.net/20.500.11755/5e976e93-3fb9-4616-8f6b-a49c2fe283d8
Publikováno v:
Clinical Cancer Research. 15:208-216
Purpose: Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity. TF is highly expressed in human colorectal tumors, and levels are positively correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb16dc8bba02a44de17ce364109a4099
https://doi.org/10.1158/1078-0432.ccr-08-0407
https://doi.org/10.1158/1078-0432.ccr-08-0407