Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Arick Brown"'
Publikováno v:
Biotechnology and Applied Biochemistry. 66:216-223
Filtration of protein A eluates inline with a chromatography column is a common challenge for monoclonal antibody (mAb) purification due to the high system backpressure during elution, which can result in system shut down or require a decreased eluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01328786da6ae4ba46ffd340938f6bee
https://doi.org/10.1002/bab.1713
https://doi.org/10.1002/bab.1713
Publikováno v:
Biotechnology and Applied Biochemistry
The present study examined the overloading of ion-exchange membrane adsorbers, a form of frontal chromatography, as the final purification step in the production of mAbs (monoclonal antibodies) produced from CHO (Chinese-hamster ovary) cells. Prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd491fc46942a73415d1e95c66b74f97
http://europepmc.org/articles/PMC2891000
http://europepmc.org/articles/PMC2891000
Autor:
Satyan Pai, Jerome Bill, Charity Bechtel, Jun Liu, Brooke Ellen Thayer, Arick Brown, Daniel Mcdonald, Hui Liu, Asha Nandini Radhamohan, Christopher F. Dowd, Stefan T. Yohe, Ryan S. Renslow
Publikováno v:
Biotechnology and bioengineering. 106(4)
Pre-filtration using ion exchange membrane adsorbers can improve parvovirus filter throughput of monoclonal antibodies (mAbs). The membranes work by binding trace foulants, and although some antibody product also binds, yields > or =99% are easily ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a3a8cbfb94565eabcb0b78bf0b0116
https://pubmed.ncbi.nlm.nih.gov/20229510
https://pubmed.ncbi.nlm.nih.gov/20229510
Publikováno v:
Biotechnology and bioengineering. 100(5)
High-performance tangential flow filtration (HPTFF) is shown to successfully enable concentration, purification and formulation in a single unit operation. This is illustrated with feedstreams comprising recombinant proteins expressed in Escherichia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b6a4ad0dd092562a759c3470fde1c7
https://pubmed.ncbi.nlm.nih.gov/18393314
https://pubmed.ncbi.nlm.nih.gov/18393314
Publikováno v:
Biotechnology & Applied Biochemistry; Jun2010, Vol. 56 Issue 2, p59-70, 12p