Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Arica A. Lubin"'
Autor:
Arica A. Lubin, Brett M. Cook, Aaron A. Rowe, Kevin W. Plaxco, Erin A. Miller, Daniel Hollis, Kelly N. Chuh
Publikováno v:
Analytical Chemistry. 83:9462-9466
Electrochemical DNA (E-DNA) sensors, which are rapid, reagentless, and readily integrated into microelectronics and microfluidics, appear to be a promising alternative to optical methods for the detection of specific nucleic acid sequences. Keeping w
Autor:
Kevin W. Plaxco, Arica A. Lubin
Publikováno v:
Accounts of Chemical Research. 43:496-505
Biomolecular recognition is versatile, specific, and high affinity, qualities that have motivated decades of research aimed at adapting biomolecules into a general platform for molecular sensing. Despite significant effort, however, so-called "biosen
Publikováno v:
Analytical Chemistry. 81:2150-2158
Previous work has described several reagentless, electrochemical DNA (E-DNA) sensing architectures comprised of an electrode-immobilized, redox-tagged probe oligonucleotide. Recent studies suggest that E-DNA signaling is predicated on hybridization-l
Publikováno v:
Proceedings of the National Academy of Sciences. 103:16677-16680
We report a signal-on, electronic DNA (E-DNA) sensor that is label-free and achieves a subpicomolar detection limit. The sensor, which is based on a target-induced strand displacement mechanism, is composed of a “capture probe” attached by its 5
Publikováno v:
Analytical Chemistry. 78:5671-5677
The ability to detect specific oligonucleotides in complex, contaminant-ridden samples, without the use of exogenous reagents and using a reusable, fully electronic platform could revolutionize the detection of pathogens in the clinic and in the fiel
Publikováno v:
Angewandte Chemie International Edition. 44:5456-5459
Label-Free, Dual-Analyte Electrochemical Biosensors: A New Class of Molecular-Electronic Logic Gates
Autor:
Xiong Gong, Fan Xia, Kevin W. Plaxco, Ryan J. White, Jonathan D. Yuen, Alexis Vallée-Bélisle, Yi Xiao, Di Kang, Renqiang Yang, Ben Y. B. Hsu, Xiaolei Zuo, Arica A. Lubin
Publikováno v:
Journal of the American Chemical Society. 132:8557-8559
An "XOR" gate built using label-free, dual-analyte electrochemical sensors and the activation of this logic gate via changing concentrations of cocaine and the relevant cDNA as inputs are described.
Autor:
Brian Scott Ferguson, H. Tom Soh, James Swensen, Arica A. Lubin, Yi Xiao, Rebecca Y. Lai, Alan J. Heeger, Kevin W. Plaxco
Publikováno v:
Journal of the American Chemical Society. 131(12)
The development of a biosensor system capable of continuous, real-time measurement of small-molecule analytes directly in complex, unprocessed aqueous samples has been a significant challenge, and successful implementation has been achieved for only
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 24(18)
Electrochemical, aptamer-based (E-AB) sensors, which are comprised of an electrode modified with surface immobilized, redox-tagged DNA aptamers, have emerged as a promising new biosensor platform. In order to further improve this technology we have s
Publikováno v:
Chemical communications (Cambridge, England). (46)
We have developed a new biosensor architecture, which is comprised of a polypeptide–peptide nucleic acid tri-block co-polymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to tha