Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Aric M Frantz"'
Autor:
Noriko Tonomura, Ingegerd Elvers, Rachael Thomas, Kate Megquier, Jason Turner-Maier, Cedric Howald, Aaron L Sarver, Ross Swofford, Aric M Frantz, Daisuke Ito, Evan Mauceli, Maja Arendt, Hyun Ji Noh, Michele Koltookian, Tara Biagi, Sarah Fryc, Christina Williams, Anne C Avery, Jong-Hyuk Kim, Lisa Barber, Kristine Burgess, Eric S Lander, Elinor K Karlsson, Chieko Azuma, Jaime F Modiano, Matthew Breen, Kerstin Lindblad-Toh
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004922 (2015)
Dogs, with their breed-determined limited genetic background, are great models of human disease including cancer. Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically simila
Externí odkaz:
https://doaj.org/article/5b00e49abada4f5abe8f6eab4d5205b1
Catalog of ex vivo whole blood stimulation conditions to generate species-specific cytokine controls
Publikováno v:
The Journal of Immunology. 204:59.32-59.32
Commercially available reagents for the detection of cytokines in pre-clinical species often rely on cross-reactivity from other species. Species-specific cytokine control materials are ideal for use in determining the suitability of the cross-reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8429e3b794b63b47990c3296070404e
https://doi.org/10.4049/jimmunol.204.supp.59.32
https://doi.org/10.4049/jimmunol.204.supp.59.32
Autor:
Jaime F. Modiano, Timothy O'Brien, Mitzi Lewellen, Jong Hyuk Kim, Aaron L. Sarver, Aric M. Frantz, Erin B. Dickerson, B. H. Gorden Klukas
Non-adherent, three-dimensional sphere formation is used as an in vitro surrogate to evaluate cellular potential for tumor initiation and self-renewal. To determine if a shared molecular program underlies the capacity for sphere formation by cells or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b91a8965c3553e583ef87fbdf5a3541
https://europepmc.org/articles/PMC5821546/
https://europepmc.org/articles/PMC5821546/
Publikováno v:
Veterinary and Comparative Oncology. 14:e113-e125
Canine hemangiosarcoma is a rapidly progressive disease that is poorly responsive to conventional chemotherapy. Despite numerous attempts to advance treatment options and improve outcomes, drug resistance remains a hurdle to successful therapy. To ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::324d4cfefb8d18771dce20852fb6c598
https://doi.org/10.1111/vco.12114
https://doi.org/10.1111/vco.12114
Publikováno v:
Veterinary Immunology and Immunopathology. 159:192-201
The term “lymphoma” describes a heterogeneous group of disorders involving monoclonal proliferation of malignant lymphocytes. As a group, lymphomas are among the most common tumors of dogs. Yet our enumeration and understanding of the many subtyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf93b1e0f0f7f022fb69b727c0055a93
https://doi.org/10.1016/j.vetimm.2014.02.016
https://doi.org/10.1016/j.vetimm.2014.02.016
Autor:
Aric M. Frantz, Daniel A. Vallera, Jill T. Schappa, Brandi H. Gorden, Jaime F. Modiano, Erin B. Dickerson
Publikováno v:
International Journal of Cancer. 133:1936-1944
Targeted toxins have the potential to overcome intrinsic or acquired resistance of cancer cells to conventional cytotoxic agents. Here, we hypothesized that EGFuPA-toxin, a bispecific ligand-targeted toxin (BLT) consisting of a deimmunized Pseudomona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e88d7fd6bb85115a794d76129daa8c7f
https://doi.org/10.1002/ijc.28187
https://doi.org/10.1002/ijc.28187
Autor:
Kerstin Lindblad-Toh, Brian D. Husbands, Timothy O'Brien, William C. Kisseberth, Matthew Breen, Lawrence Hunter, Tzu L. Phang, Daisuke Ito, Jaime F. Modiano, Kristine Burgess, Michael S. Henson, Victor E. Valli, Aaron L. Sarver, Aric M. Frantz, Antonella Borgatti, Anis Karimpour-Fard, Milcah C. Scott
Publikováno v:
Veterinary Pathology. 50:693-703
We performed genomewide gene expression analysis of 35 samples representing 6 common histologic subtypes of canine lymphoma and bioinformatics analyses to define their molecular characteristics. Three major groups were defined on the basis of gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f04475f1f072b1ff5ab64de52e166c
https://doi.org/10.1177/0300985812465325
https://doi.org/10.1177/0300985812465325
Autor:
Jaime F. Modiano, Rachael Thomas, Nicola J. Mason, Anne C. Avery, Daisuke Ito, Christina L. Williams, Aric M. Frantz, Timothy O'Brien, Robert C. Burnett, Matthew Breen
Publikováno v:
Leukemia & Lymphoma. 53:1390-1398
Established cell lines are utilized extensively to study tumor biology and preclinical therapeutic development. However, they may not accurately recapitulate the heterogeneity of their corresponding primary disease. B-cell tumor cells are especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d390cd3b0afa20de9194ef3e3c0533
https://doi.org/10.3109/10428194.2011.654337
https://doi.org/10.3109/10428194.2011.654337
Autor:
Erin B. Dickerson, Jaime F. Modiano, Leslie C. Sharkey, Sally R. Robinson, Aric M. Frantz, Kari L. Anderson, Ashley J. Graef, Timothy O'Brien, Jong Hyuk Kim, Milcah C. Scott
Publikováno v:
Experimental Cell Research. 371:299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65b374f3cf4f7e7f970f9d739ff0d813
https://doi.org/10.1016/j.yexcr.2018.07.012
https://doi.org/10.1016/j.yexcr.2018.07.012
Autor:
Jong Hyuk Kim, Lisa G. Barber, Chieko Azuma, Christina L. Williams, Sarah Fryc, Michele Koltookian, Evan Mauceli, Aaron L. Sarver, Daisuke Ito, Kristine Burgess, Cédric Howald, Tara Biagi, Rachael Thomas, Elinor K. Karlsson, Eric S. Lander, Jaime F. Modiano, Ross Swofford, Kate Megquier, Noriko Tonomura, Kerstin Lindblad-Toh, Aric M. Frantz, Anne C. Avery, Matthew Breen, Maja Louise Arendt, Jason Turner-Maier, Ingegerd Elvers, Hyun Ji Noh
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004922 (2015)
Public Library of Science
PLoS Genetics
Public Library of Science
PLoS Genetics
Dogs, with their breed-determined limited genetic background, are great models of human disease including cancer. Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c257188ca3f46d398a7e4630b98f7d
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-252254
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-252254