Výsledky vyhledávání - "Aric K. Park"

NUCLEAR FACTOR-??B TRANSCRIPTION FACTOR DECOY TREATMENT INHIBITS GRAFT CORONARY ARTERY DISEASE AFTER CARDIAC TRANSPLANTATION IN RODENTS1

Autor: Aric K. Park, Douglas N. Miniati, Robert C. Robbins, E. Grant Hoyt, Brian T. Feeley

Publikováno v: Transplantation. 70:1560-1568

BACKGROUND Nuclear factor-kappaB (NF-kappaB) is a transcription factor that upregulates adhesion molecules ICAM-1, VCAM-1, and ELAM-1. We hypothesized the use of ex vivo pressure-mediated delivery of transcription factor decoys (TFD) to NF-kappaB bin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8a8ac8b8bf99ce5843d9715e8e6695d
https://doi.org/10.1097/00007890-200012150-00005

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OPTIMIZATION OF EX VIVO PRESSURE MEDIATED DELIVERY OF ANTISENSE OLIGODEOXYNUCLEOTIDES TO ICAM-1 REDUCES REPERFUSION INJURY IN RAT CARDIAC ALLOGRAFTS1

Autor: Robert S. Poston, Aric K. Park, Robert C. Robbins, Brian T. Feeley, Michael P. Ennen, Patrick W. Vriens, Hoyt Eg

Publikováno v: Transplantation. 69:1067-1074

Background.Our purpose was to optimize hyperbaric pressure as a vector for ex vivo transfection of antisense oligodeoxynucleotides (AS-ODN) to intercellular adhesion molecule-1 to limit reperfusion injury (RI) in cardiac allografts.We investigated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::978050c6820352daec0a16573d158a31
https://doi.org/10.1097/00007890-200003270-00009

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Sulfasalazine inhibits reperfusion injury and prolongs allograft survival in rat cardiac transplants

Autor: Robert C. Robbins, E. Grant Hoyt, Aric K. Park, Brian T. Feeley

Publikováno v: The Journal of Heart and Lung Transplantation. 18:1088-1095

Reperfusion injury is an inflammatory cell-mediated response that causes tissue damage immediately following transplantation, and has been implicated in the development of acute and chronic rejection. NF-kappaB is a transcription factor that upregula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ab1d1b055ad022f85538c611c95cd5
https://doi.org/10.1016/s1053-2498(99)00078-9

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Pressure delivery of AS-ICAM-1 ODN with LFA-1 mAb reduces reperfusion injury in cardiac allografts

Autor: E. Grant Hoyt, Aric K. Park, Michael P. Ennen, Brian T. Feeley, Robert S. Poston, Sophoclis P. Alexopoulos, Robert C. Robbins

Publikováno v: The Annals of thoracic surgery. 68(1)

The goal of this study is to determine the effects of ex vivo hyperbaric pressure administration of AS-ICAM-1 ODN and systemic anti-LFA-1 mAb treatment on reperfusion injury in the rat cardiac allograft model.A PVG to ACI functional heterotopic rat h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac07c6222a540c921ba3317456395ee
https://pubmed.ncbi.nlm.nih.gov/10421126

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EX VIVO PRESSURE MEDIATED DELIVERY OF NF-KB TRANSCRIPTION FACTOR DECOYS INHIBITS MYOINTIMAL PROLIFERATION ASSOCIATED WITH GRAFT CORONARY ARTERY DISEASE IN CARDIAC ALLOGRAFTS

Autor: Aric K. Park, Douglas N. Miniati, E. Grant Hoyt, Brian T. Feeley, Robert C. Robbins

Publikováno v: Transplantation. 67:S250

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca38c7c3e28fb38e788f8173dcc6f59c
https://doi.org/10.1097/00007890-199904150-00997

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