Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Aric J. Schultz"'
Autor:
My-Hang Huynh, Marijo S. Roiko, Angelica O. Gomes, Ellyn N. Schinke, Aric J. Schultz, Swati Agrawal, Christine A. Oellig, Travis R. Sexton, Jessica M. Beauchamp, Julie Laliberté, Komagal Kannan Sivaraman, Louis B. Hersh, Sheena McGowan, Vern B. Carruthers
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
After replicating within infected host cells, the single-celled parasite Toxoplasma gondiiT. gondii
Externí odkaz:
https://doaj.org/article/edd43c30582d46ed92946c373690f57b
Autor:
Geetha Kannan, Manlio Di Cristina, Aric J. Schultz, My-Hang Huynh, Fengrong Wang, Tracey L. Schultz, Matteo Lunghi, Isabelle Coppens, Vern B. Carruthers
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Toxoplasma gondii is a ubiquitous pathogen that can cause encephalitis, congenital defects, and ocular disease. T. gondii has also been implicated as a risk factor for mental illness in humans. The parasite persists in the brain as slow-grow
Externí odkaz:
https://doaj.org/article/ae12df682df347df9a095dba059bb18f
Autor:
Aric J. Schultz, Vern B. Carruthers
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT Egress is a crucial phase of the Toxoplasma gondii intracellular lytic cycle. This is a process that drives inflammation and is strongly associated with the pathogenesis observed during toxoplasmosis. Despite the link between this process an
Externí odkaz:
https://doaj.org/article/afa3f9cf55544ce08c86333d8581b058
Autor:
Jens Eberlein, Justin Moser, Zhou Zhong, Keith A Bailey, Song-My Hoang, Aric J Schultz, Andrea Candelli, Rogier M Reijmers, Will Singleterry
Publikováno v:
The Journal of Immunology. 208:179.20-179.20
Cellular immunotherapies are increasingly complex in design. Affinity readouts, i.e., the measurements of the strength of single receptor-ligand interactions, are frequently used to assess the binding of chimeric antigen receptors (CARs) or T cell re
Autor:
Aric J. Schultz, Isabelle Coppens, Geetha Kannan, Matteo Lunghi, Fengrong Wang, Manlio Di Cristina, Tracey L. Schultz, My Hang Huynh, Vern B. Carruthers
Publikováno v:
mBio, Vol 10, Iss 4, p e01324-19 (2019)
mBio
mBio, Vol 10, Iss 4 (2019)
mBio
mBio, Vol 10, Iss 4 (2019)
Individuals chronically infected with the intracellular parasite Toxoplasma gondii are at risk of experiencing reactivated disease that can result in progressive loss of vision. No effective treatments exist for chronic toxoplasmosis due in part to a
Autor:
Fengrong Wang, Matteo Lunghi, Isabelle Coppens, Manlio Di Cristina, Geetha Kannan, Vern B. Carruthers, My Hang Huynh, Aric J. Schultz, Tracey L. Schultz
Toxoplasma gondii is a ubiquitous pathogen that can cause encephalitis, congenital defects, and ocular disease. T. gondii has also been implicated as a risk factor for mental illness in humans. The parasite persists in the brain as slow growing brady
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dead2ba3aab82c92c2dce3ef41c724
https://doi.org/10.1101/647669
https://doi.org/10.1101/647669
Autor:
Andrea Kennard, Isabelle Coppens, Julia D. Romano, Viviana Pszenny, Michael E. Grigg, Karen Ehrenman, Aric J. Schultz, David S. Roos, Vern B. Carruthers
Publikováno v:
Journal of Biological Chemistry. 291:3725-3746
The protozoan parasite Toxoplasma gondii develops within a parasitophorous vacuole (PV) in mammalian cells, where it scavenges cholesterol. When cholesterol is present in excess in its environment, the parasite expulses this lipid into the PV or este
Autor:
Manlio Di Cristina, Tracey L. Schultz, Isabelle Coppens, Wouter A. van der Linden, Sébastien Besteiro, Zhicheng Dou, Alyssa J. Miller, Matthew Bogyo, Matteo Lunghi, Geetha Kannan, Vern B. Carruthers, Beth M. Hayes, Aric J. Schultz, Carla Emiliani, Olivia L. McGovern, My Hang Huynh
Publikováno v:
Nature Microbiology. 2
Globally, nearly 2 billion people are infected with the intracellular protozoan Toxoplasma gondii1. This persistent infection can cause severe disease in immunocompromised people and is epidemiologically linked to major mental illnesses2 and cognitiv
Publikováno v:
Molecular Biology of the Cell
Although cholera toxin is a nonubiquitinated substrate that undergoes retro-translocation to the cytosol, this study identifies a deubiquitinase that controls toxin retro-translocation.
Endoplasmic reticulum (ER) membrane–bound E3 ubiquitin li
Endoplasmic reticulum (ER) membrane–bound E3 ubiquitin li
Autor:
Guerra, Alfredo J.1 galfredo@umich.edu, Carruthers, Vern B.1 vcarruth@umich.edu
Publikováno v:
Toxins. Sep2017, Vol. 9 Issue 9, p265. 15p.