Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Arianne Aslamy"'
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss , Pp 90-97 (2019)
Dietary restriction (DR) extends lifespan in a wide range of model organisms, including Caenorhabditis elegans. It is an interesting but yet to be addressed question whether hormones serve as a systemic mechanism that mediates this longevity response
Externí odkaz:
https://doaj.org/article/8f60a678c8954ddc8de00c5ea95f1fb3
Autor:
Diti Chatterjee Bhowmick, Arianne Aslamy, Supriyo Bhattacharya, Eunjin Oh, Miwon Ahn, Debbie C. Thurmond
Publikováno v:
Diabetes
Double C2 Domain Β (DOC2b) protein is required for glucose-stimulated insulin secretion (GSIS) in β-cells, the underlying mechanism of which remains unresolved. Our biochemical analysis using primary human islets, human and rodent clonal β-cells r
Autor:
Arianne Aslamy, Supriyo Bhattacharya, Debbie C. Thurmond, Miwon Ahn, Eunjin Oh, Diti Chatterjee Bhowmick
Publikováno v:
Diabetes. 70
Exocytosis regulatory protein DOC2b is a crucial regulator of SNARE assembly in β-cells and enrichment of DOC2b enhances glucose-stimulated insulin secretion (GSIS). However, the underlying mechanism of how DOC2b boosts GSIS remains to be explored.
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss, Pp 90-97 (2019)
Dietary restriction (DR) extends lifespan in a wide range of model organisms, including Caenorhabditis elegans. It is an interesting but yet to be addressed question whether hormones serve as a systemic mechanism that mediates this longevity response
Autor:
Rajakrishnan Veluthakal, Ragadeepthi Tunduguru, Erika M. Olson, Vishal A. Salunkhe, Debbie C. Thurmond, Miwon Ahn, Arianne Aslamy, Abu Saleh Md Moin, Jing Zhang, Eunjin Oh
Publikováno v:
Diabetes. 67:1332-1344
Loss of functional β-cell mass is an early feature of type 1 diabetes. To release insulin, β-cells require soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) complexes, as well as SNARE complex regulatory proteins like
Autor:
Arianne Aslamy, Eunjin Oh, Molly Duncan, Mohamed El-Shahawy, Miwon Ahn, Debbie C. Thurmond, Abu Saleh Md Moin, Fouad Kandeel, Mariann Chang, Linda A. DiMeglio, Jeannette Hacker-Stratton
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 103:1966-1976
Context Efforts to preserve β-cell mass in the preclinical stages of type 1 diabetes (T1D) are limited by few blood-derived biomarkers of β-cell destruction. Objective Platelets are proposed sources of blood-derived biomarkers for a variety of dise
Autor:
Jing Zhang, Arianne Aslamy, Rajakrishnan Veluthakal, Eunjin Oh, Ragadeepthi Tunduguru, Vishal A. Salunkhe, Miwon Ahn, Karla E. Merz, Debbie C. Thurmond
Publikováno v:
Diabetologia
AIMS/HYPOTHESIS: Skeletal muscle accounts for >80% of insulin-stimulated glucose uptake; dysfunction of this process underlies insulin resistance and type 2 diabetes. Insulin sensitivity is impaired in mice deficient in the double C2 domain β (DOC2B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6445e21689ff797f04f27582aedb14f
https://europepmc.org/articles/PMC6451670/
https://europepmc.org/articles/PMC6451670/
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Arianne Aslamy, Debbie C. Thurmond, Jing Zhang, Ragadeepthi Tunduguru, Erika M. Olson, Rajakrishnan Veluthakal, Miwon Ahn, Vishal A. Salunkhe
Publikováno v:
The FASEB Journal. 32
Autor:
Debbie C. Thurmond, Joseph T. Brozinick, Vishal A. Salunkhe, Ragadeepthi Tunduguru, Arianne Aslamy, Jeffrey S. Elmendorf, Jing Zhang
Publikováno v:
The Journal of biological chemistry. 292(46)
Defects in translocation of the glucose transporter GLUT4 are associated with peripheral insulin resistance, preclinical diabetes, and progression to type 2 diabetes. GLUT4 recruitment to the plasma membrane of skeletal muscle cells requires F-actin