Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Arianna Giacobbe"'
Autor:
Alvaro Aytes, Arianna Giacobbe, Antonina Mitrofanova, Katia Ruggero, Joanna Cyrta, Juan Arriaga, Luis Palomero, Sonia Farran-Matas, Mark A. Rubin, Michael M. Shen, Andrea Califano, Cory Abate-Shen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Identifying cell intrinsic mechanisms promoting metastasis are necessary to develop new cancer therapeutics. Here they do cross-species computational analysis and identify nuclear receptor binding SET domain Protein 2 (NSD2) as a driver of prostate c
Externí odkaz:
https://doaj.org/article/64e525ee05e54b2cbb33506e939b3948
Autor:
Mohammed Alshalalfa, Peter A. Sims, Ilsa Coleman, Jaime Yeji Kim, Angelo M. De Marzo, Onur Ertunc, Junfei Zhao, Renu K. Virk, Felix Y. Feng, Min Zou, Antonina Mitrofanova, Jun Luo, Antonio Rodriguez, Cory Abate-Shen, R. Jeffrey Karnes, Julia Fountain, Hanina Hibshoosh, Juan Arriaga, Sukanya Panja, Peter S. Nelson, Raul Rabadan, Emmanuel S. Antonarakis, Arianna Giacobbe, Busra Ozbek, Chioma J. Madubata, Mark A. Rubin
Publikováno v:
Nat Cancer
Understanding the intricacies of lethal prostate cancer poses specific challenges due to difficulties in accurate modeling of metastasis in vivo. Here we show that NPKEYFP mice (for Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e009cfc07945a1329102b75ecae0183
https://doi.org/10.1038/s43018-020-00125-0
https://doi.org/10.1038/s43018-020-00125-0
Autor:
Cory Abate-Shen, Arianna Giacobbe
Publikováno v:
Trends Cancer
Unraveling the multifaceted cellular and physiological processes associated with metastasis is best achieved by using in vivo models that recapitulate the requisite tumor cell-intrinsic and -extrinsic mechanisms at the organismal level. We discuss th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09692d918505b1d08a2fed41ef01295
https://pubmed.ncbi.nlm.nih.gov/34303648
https://pubmed.ncbi.nlm.nih.gov/34303648
Autor:
Cory Abate-Shen, Alvaro Aytes, Antonina Mitrofanova, Luis Palomero, Joanna Cyrta, Andrea Califano, Katia Ruggero, Mark A. Rubin, Michael M. Shen, Juan Arriaga, Arianna Giacobbe, Sonia Farran-Matas
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Deciphering cell-intrinsic mechanisms of metastasis progression in vivo is essential to identify novel therapeutic approaches. Here we elucidate cell-intrinsic drivers of metastatic prostate cancer progression through analyses of genetically engineer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9577e0bdb2a0c1e43ccd958cf3b4fb81
http://europepmc.org/articles/PMC6281610
http://europepmc.org/articles/PMC6281610
Autor:
A. Calvet, Miquel Angel Pujana, Alvaro Aytes, Luis Palomero, Antonina Mitrofanova, Katia Ruggero, Andrea Califano, Cory Abate-Shen, Arianna Giacobbe
Publikováno v:
European Urology Supplements. 16:e249-e250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a11364b133ca084b3d0e6908ede09cef
https://doi.org/10.1016/s1569-9056(17)30215-4
https://doi.org/10.1016/s1569-9056(17)30215-4
Autor:
Alexey V. Antonov, E K Markert, J H Zhou, Angelo Peschiaroli, Gennaro Melino, Mirco Compagnone, Margherita Annicchiarico-Petruzzelli, Arianna Giacobbe, Lucilla Bongiorno-Borbone
Publikováno v:
Oncogene (Basingstoke) 35 (2016): 1602–1608. doi:10.1038/onc.2015.230
info:cnr-pdr/source/autori:Giacobbe, A.; Compagnone, M.; Bongiorno-Borbone, L.; Antonov, A.; Markert, E. K.; Zhou, J. H.; Annicchiarico-Petruzzelli, M.; Melino, G.; Peschiaroli, A./titolo:p63 controls cell migration and invasion by transcriptional regulation of MTSS1/doi:10.1038%2Fonc.2015.230/rivista:Oncogene (Basingstoke)/anno:2016/pagina_da:1602/pagina_a:1608/intervallo_pagine:1602–1608/volume:35
info:cnr-pdr/source/autori:Giacobbe, A.; Compagnone, M.; Bongiorno-Borbone, L.; Antonov, A.; Markert, E. K.; Zhou, J. H.; Annicchiarico-Petruzzelli, M.; Melino, G.; Peschiaroli, A./titolo:p63 controls cell migration and invasion by transcriptional regulation of MTSS1/doi:10.1038%2Fonc.2015.230/rivista:Oncogene (Basingstoke)/anno:2016/pagina_da:1602/pagina_a:1608/intervallo_pagine:1602–1608/volume:35
Metastasis is a multistep cell-biological process, which is orchestrated by many factors, including metastasis activators and suppressors. Metastasis Suppressor 1 (MTSS1) was originally identified as a metastasis suppressor protein whose expression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9758958bf2ee5ed020ab57cb0259107b
http://hdl.handle.net/2108/239692
http://hdl.handle.net/2108/239692
Autor:
Ruggero De Maria, Mirco Compagnone, Angelo Peschiaroli, Adriana Eramo, Gerry Melino, Arianna Giacobbe, Lucilla Bongiorno-Borbone
Publikováno v:
Oncotarget
Europe PubMed Central
Aging (Albany NY)
Oncotarget 6 (2015): 16926–16938. doi:10.18632/oncotarget.4700
info:cnr-pdr/source/autori:Bongiorno-Borbone, Lucilla; Giacobbe, Arianna; Compagnone, Mirco; Eramo, Adriana; De Maria, Ruggero; Peschiaroli, Angelo; Melino, Gerry/titolo:Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells/doi:10.18632%2Foncotarget.4700/rivista:Oncotarget/anno:2015/pagina_da:16926/pagina_a:16938/intervallo_pagine:16926–16938/volume:6
Europe PubMed Central
Aging (Albany NY)
Oncotarget 6 (2015): 16926–16938. doi:10.18632/oncotarget.4700
info:cnr-pdr/source/autori:Bongiorno-Borbone, Lucilla; Giacobbe, Arianna; Compagnone, Mirco; Eramo, Adriana; De Maria, Ruggero; Peschiaroli, Angelo; Melino, Gerry/titolo:Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells/doi:10.18632%2Foncotarget.4700/rivista:Oncotarget/anno:2015/pagina_da:16926/pagina_a:16938/intervallo_pagine:16926–16938/volume:6
Lung cancer is the most feared of all cancers because of its heterogeneity and resistance to available treatments. Cancer stem cells (CSCs) are the cell population responsible for lung cancer chemoresistance and are a very good model for testing new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45ffda442377a5a9f7a64db3f517652
http://hdl.handle.net/2108/240140
http://hdl.handle.net/2108/240140
Autor:
Massimilano Agostini, Alessandro Finazzi Agrò, Lucilla Bongiorno-Borbone, Alessandro Terrinoni, Arnold J. Levine, Lello Zolla, Daniel A. Notterman, Angelo Peschiaroli, Arianna Giacobbe, Gerry Melino, Zhaohui Feng, Francesca Bernassola, Elke Markert
Publikováno v:
Cell cycle (Georget. Tex.) 12 (2013): 1395–1405. doi:10.4161/cc.24478
info:cnr-pdr/source/autori:Giacobbe Arianna1; Bongiorno-Borbone Lucilla1; Bernassola Francesca1; Terrinoni Alessandro2; Markert Elke Katrin3; Levine Arnold J.3; Feng Zhaohui4; Agostini Massimiliano5; Zolla Lello6; Finazzi Agrò Alessandro1; Notterman Daniel A.7, Melino Gerry8,9; Peschiaroli Angelo10/titolo:p63 regulates glutaminase 2 expression/doi:10.4161%2Fcc.24478/rivista:Cell cycle (Georget. Tex.)/anno:2013/pagina_da:1395/pagina_a:1405/intervallo_pagine:1395–1405/volume:12
info:cnr-pdr/source/autori:Giacobbe Arianna1; Bongiorno-Borbone Lucilla1; Bernassola Francesca1; Terrinoni Alessandro2; Markert Elke Katrin3; Levine Arnold J.3; Feng Zhaohui4; Agostini Massimiliano5; Zolla Lello6; Finazzi Agrò Alessandro1; Notterman Daniel A.7, Melino Gerry8,9; Peschiaroli Angelo10/titolo:p63 regulates glutaminase 2 expression/doi:10.4161%2Fcc.24478/rivista:Cell cycle (Georget. Tex.)/anno:2013/pagina_da:1395/pagina_a:1405/intervallo_pagine:1395–1405/volume:12
The transcription factor p63 is critical for many biological processes, including development and maintenance of epidermal tissues and tumorigenesis. Here, we report that the TAp63 isoforms regulate cell metabolism through the induction of the mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f5bf0d19677a8a6ee6f37baeb9878f
https://europepmc.org/articles/PMC3674067/
https://europepmc.org/articles/PMC3674067/
Autor:
Eleonora Candi, Arnold J. Levine, Arianna Giacobbe, Amanda Formosa, Gerry Melino, E K Markert, Lucilla Bongiorno-Borbone, A. Finazzi Agrò, Lello Zolla, Angelo Peschiaroli, Angelo D'Alessandro
Publikováno v:
Oncogene (Basingstoke) 32 (2013): 797–802. doi:10.1038/onc.2012.100
info:cnr-pdr/source/autori:A. Peschiaroli 1-2; A. Giacobbe 3; A. Formosa 2; E.K. Markert 4; L. Bongiorno-Borbone 3; A.J. Levine 4; E. Candi 3; A. D'Alessandro 5; L. Zolla 5; A. Finazzi Agrò 3; G. Melino2-6/titolo:miR-143 regulates hexokinase 2 expression in cancer cells/doi:10.1038%2Fonc.2012.100/rivista:Oncogene (Basingstoke)/anno:2013/pagina_da:797/pagina_a:802/intervallo_pagine:797–802/volume:32
info:cnr-pdr/source/autori:A. Peschiaroli 1-2; A. Giacobbe 3; A. Formosa 2; E.K. Markert 4; L. Bongiorno-Borbone 3; A.J. Levine 4; E. Candi 3; A. D'Alessandro 5; L. Zolla 5; A. Finazzi Agrò 3; G. Melino2-6/titolo:miR-143 regulates hexokinase 2 expression in cancer cells/doi:10.1038%2Fonc.2012.100/rivista:Oncogene (Basingstoke)/anno:2013/pagina_da:797/pagina_a:802/intervallo_pagine:797–802/volume:32
Tumor cells activate pathways that facilitate and stimulate glycolysis even in the presence of adequate levels of oxygen in order to satisfy their continuous need of molecules, such as nucleotides, ATP and fatty acids, necessary to support their rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152cce1cfaedbc3ad86e2ab9f72d0857
http://hdl.handle.net/2108/102676
http://hdl.handle.net/2108/102676
Autor:
Arianna Giacobbe, Federica Francescangeli, Mary Anna Venneri, Cristina Colarossi, Antonio Addario, Marcello Maugeri-Saccà, Mario Falchi, Leonardo D'Urso, M Patrizii, Devis Collura, Marco Biffoni, Maria Letizia Musumeci, Giovanni Muto, Désirée Bonci, Lorenzo Memeo, R De Maria, Valeria Coppola
Publikováno v:
Oncogene. 30(41)
The interaction between cancer cells and microenvironment has a critical role in tumor development and progression. Although microRNAs regulate all the major biological mechanisms, their influence on tumor microenvironment is largely unexplored. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579d936dd7d397b6d19bd0baadb108b7
https://pubmed.ncbi.nlm.nih.gov/21532615
https://pubmed.ncbi.nlm.nih.gov/21532615