Výsledky vyhledávání - "Ariane de Jesus Sousa-Batista"

Novel and safe single-dose treatment of cutaneous leishmaniasis with implantable amphotericin B-loaded microparticles

Autor: Bartira Rossi-Bergmann, Maria Inês Ré, Ariane de Jesus Sousa-Batista, Wallace Pacienza-Lima

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss, Pp 148-155 (2019)
International journal for parasitology. Drugs and drug resistance
International journal for parasitology. Drugs and drug resistance, Elsevier, 2019, 11, pp.148-155. ⟨10.1016/j.ijpddr.2019.06.001⟩

The development of an effective amphotericin B (AmB) topical formulation to replace the systemically toxic injections currently used in cutaneous leishmaniasis (CL) treatment is challenging due to poor absorption through the skin. Aiming at an effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5279f0cc14575317f65a89e8a5def0a9
http://europepmc.org/articles/PMC6904829

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Leishmanicidal therapy targeted to parasite proteases

Autor: Ariane de Jesus Sousa-Batista, Suzana Passos Chaves, Monique Pacheco Duarte Carneiro, Herbert Leonel de Matos Guedes, Ana Paula C. A. Lima, Ana Carolina Rennó Sodero, Francisco J. P. Lopes, Patrícia de Almeida Machado

Publikováno v: Life Sciences. 219:163-181

Leishmaniasis is considered a serious public health problem and the current available therapy has several disadvantages, which makes the search for new therapeutic targets and alternative treatments extremely necessary. In this context, this review f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db6738dda8e0454474ce51eed9c1009
https://doi.org/10.1016/j.lfs.2019.01.015

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Single-dose treatment for cutaneous leishmaniasis with an easily synthesized chalcone entrapped in polymeric microparticles

Autor: Franceline Reynaud, Natalia Arruda-Costa, Ariane de Jesus Sousa-Batista, Patrick G. Steel, Douglas O Escrivani, Bartira Rossi-Bergmann

Publikováno v: Parasitology
Parasitology, 2020, Vol.147(9), pp.1032-1037 [Peer Reviewed Journal]

Cutaneous leishmaniasis (CL) is a major health problem in many countries and its current treatment involves multiple parenteral injections with toxic drugs and requires intensive health services. Previously, the efficacy of a single subcutaneous inje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64d91c29aaecc35f3478f5cad2e0cda
https://europepmc.org/articles/PMC10317656/

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New chalcone compound as a promising antileishmanial drug for an old neglected disease: Biological evaluation using radiolabelled biodistribution

Autor: Ralph Santos-Oliveira, Suyene Rocha Pinto, Ariane de Jesus Sousa-Batista, Cintia Iana Monteiro da Silva Philipon, Bartira Rossi-Bergmann, Marta de Souza Albernaz

Publikováno v: Journal of Global Antimicrobial Resistance. 13:139-142

Objectives Treatment of leishmaniasis remains a challenge, especially due to the need for multiple painful injections, the toxicity of current drugs against the disease, their lack of efficacy and, lately, drug resistance. The aim of this study was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e93f85c46491fbc69e4885c468437f0
https://doi.org/10.1016/j.jgar.2017.11.012

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Lipid-core nanocapsules increase the oral efficacy of quercetin in cutaneous leishmaniasis

Autor: Ariane de Jesus Sousa-Batista, Bartira Rossi-Bergmann, Adriana Raffin Pohlmann, Fernanda Poletto, Cintia Iana Monteiro da Silva Philipon, S.S. Guterres

Publikováno v: Parasitology. 144:1769-1774

SUMMARYNew oral treatments are needed for all forms of leishmaniasis. Here, the improved oral efficacy of quercetin (Qc) and its penta-acetylated derivative (PQc) was evaluated in cutaneous leishmaniasis after encapsulation in lipid-core nanocapsules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886b58ccae3d9afd732f3772ad3facae
https://doi.org/10.1017/s003118201700097x

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Encapsulation in lipid-core nanocapsules improves topical treatment with the potent antileishmanial compound CH8

Autor: Stela Regina Ferrarini, Fernanda Poletto, Patrick G. Steel, Bartira Rossi-Bergmann, Ariane de Jesus Sousa-Batista, Milene V. Lopes, Silvia Stanisçuaski Guterres, Douglas O Escrivani, Adriana Raffin Pohlmann

Publikováno v: Nanomedicine : nanotechnology, biology and medicine, 2020, Vol.24, pp.102121 [Peer Reviewed Journal]

Cutaneous leishmaniasis (CL) is a neglected parasitic disease conventionally treated by multiple injections with systemically toxic drugs. Aiming at a more acceptable therapy, we developed lipid-core nanocapsules (LNCs) entrapping the potent antileis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b805c110db8d44e8180e3016dffbd88c
https://pubmed.ncbi.nlm.nih.gov/31672601

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Polycaprolactone Antimony Nanoparticles as Drug Delivery System for Leishmaniasis

Autor: Fagner Santos do Carmo, Ralph Santos-Oliveira, Marta de Souza Albernaz, Ariane de Jesus Sousa-Batista, Cristal Cerqueira-Coutinho

Publikováno v: American journal of therapeutics. 26(1)

BACKGROUND Leishmaniasis is a neglected disease endemic in tropical and subtropical areas, with an incidence about 1.6 million cases/year. The first-line treatment of this disease is pentavalent antimony, and the second-line are pentamidine and ampho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56ed648d3ec728389feb2aeb0f7f9fe
https://pubmed.ncbi.nlm.nih.gov/30601770

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