Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ariane R, Pessentheiner"'
Autor:
Melina Amor, Valentina Bianco, Martin Buerger, Margarete Lechleitner, Nemanja Vujić, Anja Dobrijević, Alena Akhmetshina, Anita Pirchheim, Birgit Schwarz, Ariane R. Pessentheiner, Franziska Baumgartner, Katharina Rampitsch, Silvia Schauer, Iva Klobučar, Vesna Degoricija, Gudrun Pregartner, Daniel Kummer, Monika Svecla, Gerhard Sommer, Dagmar Kolb, Gerhard A. Holzapfel, Gerald Hoefler, Saša Frank, Giuseppe Danilo Norata, Dagmar Kratky
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Background Matrix metalloproteinase 12 (MMP12) is a macrophage-secreted protein that is massively upregulated as a pro-inflammatory factor in metabolic and vascular tissues of mice and humans suffering from cardiometabolic diseases (CMDs). H
Externí odkaz:
https://doaj.org/article/90391e7f6b60445e9f1c67e516663e8f
Autor:
Bastian Ramms, Sohan Patel, Xiaoli Sun, Ariane R. Pessentheiner, G. Michelle Ducasa, Adam E. Mullick, Richard G. Lee, Rosanne M. Crooke, Sotirios Tsimikas, Joseph L. Witztum, Philip L.S.M. Gordts
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
Apolipoprotein C-III (apoC-III) is a critical regulator of triglyceride metabolism and correlates positively with hypertriglyceridemia and cardiovascular disease (CVD). It remains unclear if therapeutic apoC-III lowering reduces CVD risk and if the C
Externí odkaz:
https://doaj.org/article/d3c85ea05ac64087a50365d3f59dcc54
Autor:
Bastian Ramms, Sohan Patel, Chelsea Nora, Ariane R. Pessentheiner, Max W. Chang, Courtney R. Green, Gregory J. Golden, Patrick Secrest, Ronald M. Krauss, Christian M. Metallo, Christopher Benner, Veronica J. Alexander, Joseph L. Witztum, Sotirios Tsimikas, Jeffrey D. Esko, Philip L.S.M. Gordts
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 8, Pp 1379-1395 (2019)
Hypertriglyceridemia results from accumulation of triglyceride (TG)-rich lipoproteins (TRLs) in the circulation and is associated with increased CVD risk. ApoC-III is an apolipoprotein on TRLs and a prominent negative regulator of TG catabolism. We r
Externí odkaz:
https://doaj.org/article/79b2fc472cb54420abab601c33268491
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Proteoglycans are a specific subset of glycoproteins found at the cell surface and in the extracellular matrix, where they interact with a plethora of proteins involved in metabolic homeostasis and meta-inflammation. Over the last decade, new insight
Externí odkaz:
https://doaj.org/article/43ba2b7ad6464ec6a17548e2ac0b0ac6
Autor:
Rafael Mayoral, Olivia Osborn, Joanne McNelis, Andrew M. Johnson, Da Young Oh, Cristina Llorente Izquierdo, Heekyung Chung, Pingping Li, Paqui G. Traves, Gautam Bandyopadhyay, Ariane R. Pessentheiner, Jachelle M. Ofrecio, Joshua R. Cook, Li Qiang, Domenico Accili, Jerrold M. Olefsky
Publikováno v:
Molecular Metabolism, Vol 4, Iss 5, Pp 378-391 (2015)
Objective: Adipose tissue is the primary site for lipid deposition that protects the organisms in cases of nutrient excess during obesogenic diets. The histone deacetylase Sirtuin 1 (SIRT1) inhibits adipocyte differentiation by targeting the transcri
Externí odkaz:
https://doaj.org/article/aa5602b006754977b466515665297212
Autor:
Miguel Tillo, William C. Lamanna, Chrissa A. Dwyer, Daniel R. Sandoval, Ariane R. Pessentheiner, Norah Al-Azzam, Stéphane Sarrazin, Jon C. Gonzales, Shih-Hsin Kan, Alexander Y. Andreyev, Nicholas Schultheis, Bryan E. Thacker, Charles A. Glass, Patricia I. Dickson, Raymond Y. Wang, Scott B. Selleck, Jeffrey D. Esko, Philip L.S.M. Gordts
Publikováno v:
The Journal of biological chemistry, vol 298, iss 8
Lysosomal storage diseases result in various developmental and physiological complications, including cachexia. To study the causes for the negative energy balance associated with cachexia, we assessed the impact of sulfamidase deficiency and heparan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aac85804ae2331b1d014955f84e8ad4
https://escholarship.org/uc/item/90c4v3np
https://escholarship.org/uc/item/90c4v3np
Autor:
Evelyn Walenta, Ariane R Pessentheiner, Helmut J Pelzmann, Alexander Deutsch, Madeleine Goeritzer, Dagmar Kratky, Hubert Hackl, Da Young Oh, Andreas Prokesch, Juliane G Bogner-Strauss
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79134 (2013)
Our knowledge about adipocyte metabolism and development is steadily growing, yet many players are still undefined. Here, we show that α/β-hydrolase domain containing protein 15 (Abhd15) is a direct and functional target gene of peroxisome prolifer
Externí odkaz:
https://doaj.org/article/1727e6c122874af2b0a53542d0cd7380
Autor:
Wenmin, Xia, Ariane R, Pessentheiner, Dina C, Hofer, Melina, Amor, Renate, Schreiber, Gabriele, Schoiswohl, Thomas O, Eichmann, Evelyn, Walenta, Bianca, Itariu, Gerhard, Prager, Hubert, Hackl, Thomas, Stulnig, Dagmar, Kratky, Thomas, Rülicke, Juliane G, Bogner-Strauss
Publikováno v:
Cell reports
Summary Elevated circulating fatty acids (FAs) contribute to obesity-associated metabolic complications, but the mechanisms by which insulin suppresses lipolysis are poorly understood. We show that α/β-hydrolase domain-containing 15 (ABHD15) is req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd0c5bd8eee65f191bb2a9f2d7da60f4
https://pubmed.ncbi.nlm.nih.gov/29768196
https://pubmed.ncbi.nlm.nih.gov/29768196
Autor:
Ariane R, Pessentheiner, Katharina, Huber, Helmut J, Pelzmann, Andreas, Prokesch, Franz P W, Radner, Heimo, Wolinski, Josefine, Lindroos-Christensen, Gerald, Hoefler, Thomas, Rülicke, Ruth, Birner-Gruenberger, Martin, Bilban, Juliane G, Bogner-Strauss
Publikováno v:
The FASEB Journal
Adipocyte plasma membrane–associated protein (APMAP) has been described as an adipogenic factor in 3T3-L1 cells with unknown biochemical function; we therefore aimed to investigate the physiologic function of APMAP in vivo. We generated Apmap-knock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53cf0fbf4a0a893b6de42a91f0623fd4
https://pubmed.ncbi.nlm.nih.gov/28559441
https://pubmed.ncbi.nlm.nih.gov/28559441
Autor:
Dina C, Hofer, Ariane R, Pessentheiner, Helmut J, Pelzmann, Stefanie, Schlager, Corina T, Madreiter-Sokolowski, Dagmar, Kolb, Thomas O, Eichmann, Gerald, Rechberger, Martin, Bilban, Wolfgang F, Graier, Dagmar, Kratky, Juliane G, Bogner-Strauss
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids
The importance of peroxisomes for adipocyte function is poorly understood. Herein, we provide insights into the critical role of peroxin 16 (PEX16)-mediated peroxisome biogenesis in adipocyte development and lipid metabolism. Pex16 is highly expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4ff4f21373634f1f7f71126f9cdbe24
https://pubmed.ncbi.nlm.nih.gov/28017862
https://pubmed.ncbi.nlm.nih.gov/28017862