Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ariane Menden"'
Autor:
Ariane Menden, Davane Hall, Coral Hahn-Townsend, Courtney A. Broedlow, Utsav Joshi, Andrew Pearson, Fiona Crawford, James E. Evans, Nichole Klatt, Stefan Crynen, Michael Mullan, Ghania Ait-Ghezala
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Alzheimer’s disease (AD) represents the most common form of dementia in the elderly with no available disease modifying treatments. Altered gut microbial composition has been widely acknowledged as a common feature of AD, which potentially
Externí odkaz:
https://doaj.org/article/ae27d950c5b64c019808ca68dc5cb0b7
Autor:
Ariane Menden, Davane Hall, Daniel Paris, Venkatarian Mathura, Fiona Crawford, Michael Mullan, Stefan Crynen, Ghania Ait-Ghezala
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1474-1480 (2019)
The discovery of allosteric modulators is a multi-disciplinary approach, which is time- and cost-intensive. High-throughput screening combined with novel computational tools can reduce these factors. Thus, we developed an enzyme activity assay, which
Externí odkaz:
https://doaj.org/article/c66e6599375d4ab88b1fd7842725e0cc
Autor:
V. Mathura, Daniel Paris, Fiona Crawford, Stefan Crynen, Ariane Menden, Michael Mullan, Ghania Ait-Ghezala
Publikováno v:
Bioorganic chemistry. 109
Candida rugosa lipase (CRL) is an enzyme commonly used in medicinal and biotechnological applications. Allosteric modulators of CRL could aid in modifying lipase-related diseases as well as improving biotechnological processes. Thus, a combinatorial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad94ff852d1b1042fbb85b69d6d7f10
https://pubmed.ncbi.nlm.nih.gov/33639364
https://pubmed.ncbi.nlm.nih.gov/33639364
Autor:
Fiona Crawford, Davane Hall, Stefan Crynen, Courtney Ann Broedlow, Nichole R. Klatt, Ariane Menden, Teresa Darcey, Michael Mullan, Ghania Ait-Ghezala
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 130, Iss, Pp 110579-(2020)
Diet and commercially available supplements can significantly impact the gut microbial composition; however, the effects of supplements often lack scientific data demonstrating the effects on healthy and diseased individuals. Hence, it was investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56e2e1e2f058db3d36c1c01ebb4bc7f
http://www.sciencedirect.com/science/article/pii/S0753332220307721
http://www.sciencedirect.com/science/article/pii/S0753332220307721
Autor:
Michael Mullan, V. Mathura, Ghania Ait-Ghezala, Davane Hall, Stefan Crynen, Fiona Crawford, Daniel Paris, Ariane Menden
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1474-1480 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
The discovery of allosteric modulators is a multi-disciplinary approach, which is time- and cost-intensive. High-throughput screening combined with novel computational tools can reduce these factors. Thus, we developed an enzyme activity assay, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb27c7ca7af15a30434ba0b40b5e391
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d69bcbda5c148399b6dd455f8c4cee6
https://doi.org/10.1096/fasebj.2018.32.1_supplement.800.10
https://doi.org/10.1096/fasebj.2018.32.1_supplement.800.10