Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ariane C. Scheuren"'
Autor:
Francisco C. Marques, Daniele Boaretti, Matthias Walle, Ariane C. Scheuren, Friederike A. Schulte, Ralph Müller
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Mechanical loading is a key factor governing bone adaptation. Both preclinical and clinical studies have demonstrated its effects on bone tissue, which were also notably predicted in the mechanostat theory. Indeed, existing methods to quantify bone m
Externí odkaz:
https://doaj.org/article/8c8512fb040040a3959749802462c3cc
Autor:
Graeme R. Paul, Paul Vallaster, Michelle Rüegg, Ariane C. Scheuren, Duncan C. Tourolle, Gisela A. Kuhn, Esther Wehrle, Ralph Müller
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Bone healing and remodeling are mechanically driven processes. While the generalized response to mechanical stimulation in bone is well-understood, much less is known about the mechanobiology-regulating tissue-scale bone formation and resorption duri
Externí odkaz:
https://doaj.org/article/dfab17a43c7b4a1aade902e129c0d2ff
Autor:
Ariane C. Scheuren, Gommaar D'Hulst, Gisela A. Kuhn, Evi Masschelein, Esther Wehrle, Katrien De Bock, Ralph Müller
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 4, Pp 1121-1140 (2020)
Abstract Background Frailty is a geriatric syndrome characterized by increased susceptibility to adverse health outcomes. One major determinant thereof is the gradual weakening of the musculoskeletal system and the associated osteosarcopenia. To impr
Externí odkaz:
https://doaj.org/article/a99a8a388d83469c8da426eb0e6d217a
Autor:
Elena Cambria, Sally Heusser, Ariane C. Scheuren, Wai Kit Tam, Agnieszka A. Karol, Wolfgang Hitzl, Victor Y. Leung, Ralph Müller, Stephen J. Ferguson, Karin Wuertz‐Kozak
Publikováno v:
JOR Spine, Vol 4, Iss 3, Pp n/a-n/a (2021)
Abstract Background Aberrant mechanical loading of the spine causes intervertebral disc (IVD) degeneration and low back pain. Current therapies do not target the mediators of the underlying mechanosensing and mechanotransduction pathways, as these ar
Externí odkaz:
https://doaj.org/article/09a1027dccf34b24b75d28616132c272
Autor:
Ariane C. Scheuren, Paul Vallaster, Gisela A. Kuhn, Graeme R. Paul, Angad Malhotra, Yoshitaka Kameo, Ralph Müller
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
It is well-established that cyclic, but not static, mechanical loading has anabolic effects on bone. However, the function describing the relationship between the loading frequency and the amount of bone adaptation remains unclear. Using a combined e
Externí odkaz:
https://doaj.org/article/6d0950b6dda042eea8624c0a174aee44
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239534 (2020)
In vivo micro-CT has already been used to monitor microstructural changes of bone in mice of different ages and in models of age-related diseases such as osteoporosis. However, as aging is accompanied by frailty and subsequent increased sensitivity t
Externí odkaz:
https://doaj.org/article/373a35622b6242eda134cd1b588ad885
Autor:
Francisco C. Marques, Daniele Boaretti, Matthias Walle, Ariane C. Scheuren, Friederike A. Schulte, Ralph Müller
Mechanical loading is a key factor governing bone adaptation. Both preclinical and clinical studies have demonstrated its effects on bone tissue, which were also notably predicted in the mechanostat theory. Indeed, existing methods to quantify bone m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e917ea956f5394e7b13e8c0f876c80d
https://doi.org/10.1101/2023.01.07.523082
https://doi.org/10.1101/2023.01.07.523082
Publikováno v:
Mechanisms of Ageing and Development. 180:11-20
The proportion of the population over the age of 65 is growing the most rapidly due to the longevity revolution. Frailty is prevalent in this age group and strongly associated with disability and hospitalization, having a significant impact on the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5ac66dd3d9b99e0fe168fc505b2e86
https://doi.org/10.1016/j.mad.2019.03.002
https://doi.org/10.1016/j.mad.2019.03.002
Autor:
Stephen J. Ferguson, Victor Y. L. Leung, Ralph Müller, Agnieszka Karol, Wai Kit Tam, Ariane C. Scheuren, Elena Cambria, Sally Heusser, Karin Wuertz-Kozak, Wolfgang Hitzl
Publikováno v:
JOR Spine, Vol 4, Iss 3, Pp n/a-n/a (2021)
JOR Spine
JOR Spine, 4 (3)
JOR Spine
JOR Spine, 4 (3)
Background Aberrant mechanical loading of the spine causes intervertebral disc (IVD) degeneration and low back pain. Current therapies do not target the mediators of the underlying mechanosensing and mechanotransduction pathways, as these are poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3253be5d20089bd93f81a3efb3b2dac7
https://doi.org/10.1002/jsp2.1149
https://doi.org/10.1002/jsp2.1149
Autor:
P. Vallaster, R. M uumlller, Ariane C. Scheuren, G. Kuhn, Angad Malhotra, Graeme R. Paul, Yoshitaka Kameo
It is well established that cyclic, but not static, mechanical loading has anabolic effects on bone. However, the function describing the relationship between the loading frequency and the amount of bone adaptation remains unclear. Using a combined e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1549329d32c117860cd5120edf6a8c9b
https://doi.org/10.1101/2020.05.15.097998
https://doi.org/10.1101/2020.05.15.097998