Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ariane Söling"'
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158390 (2016)
Few studies have assessed whether mice used as cancer models experience pain. Despite this possibility, the usual practice is to withhold analgesics as these are generally viewed as confounding. However, pain also alters cancer progression, so preven
Externí odkaz:
https://doaj.org/article/0b5cdfb3849748eea79b2a645598ab38
Autor:
Dirk Vordermark, Matthias Bache, Helge Taubert, Sven Wach, Udo Bilkenroth, Jacqueline Keßler, Swetlana Rot, Thomas Greither, Matthias Kappler, Henri Wichmann, Antje Güttler, Ariane Söling
Publikováno v:
Oncology Reports. 33:3155-3161
The roles of hypoxia-induced and stem cell-associated genes in the development of malignancy and tumour progression are well known. However, there are a limited number of studies analysing the impact of mRNA expression levels of hypoxia-induced and s
Autor:
Henrike Caysa, Martin Messerle, Roland Jacob, Bruce R. Branchini, Nadine Müther, Ariane Söling
Publikováno v:
Photochemical & Photobiological Sciences. 8:52-56
Bioluminescence imaging has evolved as a powerful tool for monitoring biological processes in vivo. As transmission efficiency of light through tissue increases greatly for wavelengths above 600 nm we examined whether a redshifted codon-optimized fir
Autor:
Ariane Söling, Nikolai G. Rainov
Publikováno v:
Reviews on Recent Clinical Trials. 1:119-131
Targeted toxins represent a new class of agents with high specificity for tumor cells. Toxins in current clinical use for the treatment of brain tumors are mostly recombinant polypeptides consisting of a tumor-selective ligand coupled to a peptide to
Publikováno v:
FEBS Letters. 527:153-158
Gene therapy employing the suicide gene/prodrug activating system Herpes simplex virus type 1 thymidine kinase (HSV-TK)/ganciclovir (GCV) is effective in killing malignant tumor cells. Labeling of the HSV-TK enzyme with fluorescent proteins makes pos
Autor:
Nikolai G. Rainov, Ariane Söling
Publikováno v:
Molecular Medicine. 7:659-667
Although current treatment modalities for malignant gliomas, such as surgery, radiation and chemotherapy, have been improved markedly in the past two decades, the prognosis of these neoplasms remains poor, the two year survival rate being approximate
Autor:
Dirk Vordermark, Jörg Illert, Antje Güttler, Ariane Söling, Maria Giebler, C. Ostheimer, Jacqueline Keßler, Henri Wichmann, Christian Strauss, Matthias Kappler, Matthias Bache, Peter Cuno
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 108(3)
Background and purpose We investigated the role of the hypoxia-associated secreted glycoprotein osteopontin (OPN) in the response of malignant glioma to radiotherapy by characterizing OPN and its splice variants in vitro and in patient material. Mate
Publikováno v:
Journal of neurovirology. 14(6)
Transcriptional targeting of viral genes is a promising strategy to achieve tumor-specific replication of oncolytic viruses. Due to its natural tropism, herpes simplex virus type 1 (HSV-1) may be an ideal tool for oncolytic therapy of brain tumors su
Publikováno v:
BJU international. 101(1)
To improve the orthotopic murine bladder cancer model by using bioluminescent (BL) MB49 tumour cells for noninvasive in vivo monitoring of tumour growth and to examine the efficacy of integrin receptor-blocking oligopeptides on preventing tumour cell
Autor:
Eva-Maria Plugge, Roland Jacob, Hans-Jürgen Holzhausen, Jörg Illert, Marc Schmitz, Nikolai G. Rainov, Ariane Söling, Bernd Weigle
Publikováno v:
International journal of oncology. 30(1)
Survivin is a member of the inhibitor of apoptosis protein (IAP) family and is frequently expressed in cancers, including meningiomas and gliomas. Survivin may be associated with tumor progression and poor prognosis of patients with brain tumors. Usi