Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ariana Soledad Poetto"'
Autor:
Rossana Roncato, Lorenzo Gerratana, Lorenza Palmero, Sara Gagno, Ariana Soledad Poetto, Elena Peruzzi, Martina Zanchetta, Bianca Posocco, Elena De Mattia, Giovanni Canil, Martina Alberti, Marco Orleni, Giuseppe Toffoli, Fabio Puglisi, Erika Cecchin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
A wide inter-individual variability in the therapeutic response to cyclin-dependent kinases 4 and 6 inhibitors (CDKis) has been reported. We herein present a case series of five patients treated with either palbociclib or ribociclib referred to our c
Externí odkaz:
https://doaj.org/article/83ec64724fef4e21a3b484b30bd6e8f3
Autor:
Martina Zanchetta, Valentina Iacuzzi, Bianca Posocco, Giorgia Bortolin, Ariana Soledad Poetto, Marco Orleni, Giovanni Canil, Michela Guardascione, Luisa Foltran, Valentina Fanotto, Fabio Puglisi, Sara Gagno, Giuseppe Toffoli
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Lenvatinib (LENVA) is an oral antineoplastic drug used for the treatment of hepatocellular carcinoma and thyroid carcinoma. LENVA therapeutic drug monitoring (TDM) should be mandatory for a precision medicine to optimize the drug dosage. To this end,
Externí odkaz:
https://doaj.org/article/f9a48936ad72401cbcdf79e1c04c6527
Autor:
Bianca Posocco, Mauro Buzzo, Ariana Soledad Poetto, Marco Orleni, Sara Gagno, Martina Zanchetta, Valentina Iacuzzi, Michela Guardascione, Fabio Puglisi, Debora Basile, Giacomo Pelizzari, Elena Marangon, Giuseppe Toffoli
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228822 (2020)
A novel LC-MS/MS method was developed for the quantification of the new cyclin dependent kinase inhibitors (CDKIs) palbociclib and ribociclib and the aromatase inhibitor letrozole used in combinatory regimen. The proposed method is appropriate to be
Externí odkaz:
https://doaj.org/article/34569d5e09024b22b48029e2e574d355
Autor:
Valentina Iacuzzi, Bianca Posocco, Martina Zanchetta, Marcella Montico, Elena Marangon, Ariana Soledad Poetto, Mauro Buzzo, Sara Gagno, Angela Buonadonna, Michela Guardascione, Bruno Casetta, Giuseppe Toffoli
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225225 (2019)
The introduction of imatinib, an oral tyrosine kinase inhibitor, as first-line standard therapy in patients with unresectable, metastatic, or recurrent gastro-intestinal stromal tumor (GIST), strongly improved their treatment outcomes. However, thera
Externí odkaz:
https://doaj.org/article/cb7a17ede8b04212b1ec2330fbbe6edd
Autor:
Martina Zanchetta, Bianca Posocco, Sara Gagno, Ariana Soledad Poetto, Marco Orleni, Giovanni Canil, Michela Guardascione, Fabio Puglisi, Giuseppe Toffoli
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 226:115255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2490e92cffb771189ec1b329e4244db0
https://doi.org/10.1016/j.jpba.2023.115255
https://doi.org/10.1016/j.jpba.2023.115255
Autor:
Ariana, Soledad Poetto, Bianca, Posocco, Martina, Zanchetta, Sara, Gagno, Marco, Orleni, Giovanni, Canil, Martina, Alberti, Fabio, Puglisi, Giuseppe, Toffoli
Publikováno v:
Journal of Chromatography B. 1207:123403
Abemaciclib (ABEMA) is the last CDKi approved for the treatment of breast cancer. Adverse reactions to this drug are not experienced in the same manner by the entire patient population but in case of severe toxicity dose reductions and therapy discon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1694ffd4f3eef9ce924dbe053484f474
https://doi.org/10.1016/j.jchromb.2022.123403
https://doi.org/10.1016/j.jchromb.2022.123403
Autor:
Luisa Foltran, Giovanni Canil, Ariana Soledad Poetto, Giorgia Bortolin, Sara Gagno, Valentina Fanotto, Bianca Posocco, Valentina Iacuzzi, Marco Orleni, Martina Zanchetta, Giuseppe Toffoli, Fabio Puglisi, Michela Guardascione
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0259137 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0259137 (2021)
Lenvatinib (LENVA) is an oral antineoplastic drug used for the treatment of hepatocellular carcinoma and thyroid carcinoma. LENVA therapeutic drug monitoring (TDM) should be mandatory for a precision medicine to optimize the drug dosage. To this end,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066f600be4184092f243e8137e2b2a95
http://hdl.handle.net/11577/3409285
http://hdl.handle.net/11577/3409285
Autor:
Martina Zanchetta, Ariana Soledad Poetto, Bianca Posocco, Sara Gagno, Giuseppe Toffoli, Michela Guardascione, Valentina Iacuzzi
Background: Anticancer drugs are notoriously characterized by a low therapeutic index, the introduction of therapeutic drug monitoring (TDM) in oncologic clinical practice could therefore be fundamental to improve treatment efficacy. In this context,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0852128d1d8322dc5f99b68f323a28
http://hdl.handle.net/11368/2999663
http://hdl.handle.net/11368/2999663
Autor:
Ariana Soledad Poetto, Bianca Posocco, Ottavia Bellotto, Anna Meneghello, Stefano Tartaggia, Giuseppe Toffoli, Martina Zanchetta, Federico Polo, David Bunka
The anticancer drug imatinib is often involved in therapeutic drug monitoring (TDM) studies aimed at improving the treatment of several forms of leukemia and gastrointestinal stromal tumors (GIST). To further implement the TDM of imatinib in clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d130eedba9241521902ca79ae5057fe4
http://hdl.handle.net/11577/3365645
http://hdl.handle.net/11577/3365645
Autor:
Valentina Iacuzzi, Martina Zanchetta, Luisa Foltran, Sara Gagno, Ariana Soledad Poetto, Bianca Posocco, Marco Orleni, Giuseppe Toffoli, Michela Guardascione, Elena Marangon
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 187
A liquid chromatography-tandem mass spectrometry (LC–MS/MS) method was developed and validated for the simultaneous quantification of sorafenib (SORA), its N-oxide active metabolite and of regorafenib (REGO) and its two active metabolites regorafen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4d686cb5c7a0c947c9b8d197c9235f
https://pubmed.ncbi.nlm.nih.gov/32460216
https://pubmed.ncbi.nlm.nih.gov/32460216