Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ariana S. Bratt"'
Autor:
Wai Cheung Chan, Xiaoxi Liu, Robert S. Magin, Nicholas M. Girardi, Scott B. Ficarro, Wanyi Hu, Maria I. Tarazona Guzman, Cara A. Starnbach, Alejandra Felix, Guillaume Adelmant, Anthony C. Varca, Bin Hu, Ariana S. Bratt, Ethan DaSilva, Nathan J. Schauer, Isabella Jaen Maisonet, Emma K. Dolen, Anthony X. Ayala, Jarrod A. Marto, Sara J. Buhrlage
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Deubiquitinases (DUBs) are key signaling enzymes, many of which lack selective inhibitors. Chan et al. pair a DUB-focused covalent library to mass spectrometry activity-based protein profiling, leading to selective hits against 23 endogenous DUBs and
Externí odkaz:
https://doaj.org/article/d6b807ef0bbf47468c2c964d3363d37f
Autor:
He Zhu, J. Scott Mellors, Wai Cheung Chan, J. Will Thompson, Scott B. Ficarro, Isidoro Tavares, Ariana S. Bratt, Jens Decker, Michael Krause, Gary Kruppa, Sara J. Buhrlage, Jarrod A. Marto
Publikováno v:
Analytical Chemistry. 94:9508-9513
The family of deubiquitinases (DUBs) comprises ∼100 enzymes that cleave ubiquitin from substrate proteins and thereby regulate key aspects of human physiology. DUBs have recently emerged as disease-relevant and chemically tractable, although curren
Publikováno v:
Israel Journal of Chemistry. 63
Autor:
Xiaoxi Liu, Alejandra Felix, Wai Cheung Chan, Ariana S. Bratt, Sara J. Buhrlage, Robert S. Magin
Publikováno v:
Cell Chemical Biology. 28:1090-1100
Deubiquitinating enzymes (DUBs) are a largely understudied and untapped resource in the toolkit of protein degradation functionalities. They comprise a large repertoire of enzymes that remove ubiquitin from substrates in a variety of cellular and pat
Autor:
Arnab Mukherjee, JungHo Kang, Oleksandr Kuznetsov, Yanqiu Sun, Ryan Thaner, Ariana S. Bratt, Jay R. Lomeda, Kevin F. Kelly, W. E. Billups
Publikováno v:
Chemistry of Materials; Jan2011, Vol. 23 Issue 1, p9-13, 5p