Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ariana N Tkachuk"'
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142436 (2015)
Mitochondrial DNA (mtDNA) is maintained within nucleoprotein complexes known as nucleoids. These structures are highly condensed by the DNA packaging protein, mitochondrial Transcription Factor A (TFAM). Nucleoids also include RNA, RNA:DNA hybrids, a
Externí odkaz:
https://doaj.org/article/d2818b4444c4448db59f4b565e18fb9c
Publikováno v:
ACS Central Science, Vol 3, Iss 9, Pp 975-985 (2017)
Externí odkaz:
https://doaj.org/article/00cfbf91c313491a8ff5bf6dd5a20e67
Autor:
Heejun Choi, Zhe Liu, Natalie Falco, Jennifer Lippincott-Schwartz, Liangqi Xie, Benjamin S. Glick, Luke D. Lavis, Jason C. Casler, Jonathan B. Grimm, Ariana N. Tkachuk, Timothy A. Brown, Ronak Patel
Publikováno v:
JACS Au, Vol 1, Iss 5, Pp 690-696 (2021)
Jacs Au
Jacs Au
Fluorescence microscopy relies on dyes that absorb and then emit photons. In addition to fluorescence, fluorophores can undergo photochemical processes that decrease quantum yield or result in spectral shifts and irreversible photobleaching. Chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f580f462436964311800665f9a22b91
https://doi.org/10.1021/jacsau.1c00006
https://doi.org/10.1021/jacsau.1c00006
Autor:
Jonathan B. Grimm, Boaz Mohar, Liangqi Xie, Natalie Falco, Ariana N. Tkachuk, Zhe Liu, Jennifer Lippincott-Schwartz, Qinsi Zheng, Kathy Schaefer, Luke D. Lavis, Heejun Choi, Timothy A. Brown, Ronak Patel
Publikováno v:
Nature methods
Expanding the palette of fluorescent dyes is vital to push the frontier of biological imaging. Although rhodamine dyes remain the premier type of small-molecule fluorophore owing to their bioavailability and brightness, variants excited with far-red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630d25ed5b4345428d0a8bf0836fc5ca
https://doi.org/10.1038/s41592-020-0909-6
https://doi.org/10.1038/s41592-020-0909-6
Autor:
Sambashiva Banala, Ariana N. Tkachuk, Ronak Patel, Pratik Kumar, Timothy A. Brown, Luke D. Lavis
Publikováno v:
ACS biomed chem Au. 2(3)
Small-molecule fluorescent stains enable the imaging of cellular structures without the need for genetic manipulation. Here, we introduce 2,7-diaminobenzopyrylium (DAB) dyes as live-cell mitochondrial stains excited with violet light. This amalgam of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae9b44c02208ace2c2fb3139ecb883c
https://pubmed.ncbi.nlm.nih.gov/35726328
https://pubmed.ncbi.nlm.nih.gov/35726328
Autor:
Anthony X. Ayala, Jennifer Lippincott-Schwartz, Carl Wu, Aubrey V. Weigel, Ariana N. Tkachuk, Robert H. Singer, Natalie Falco, Qinsi Zheng, Jonathan B. Grimm, Inhee Chung, Luke D. Lavis, Anand Ranjan
Publikováno v:
ACS Central Science
ACS Central Science, Vol 5, Iss 9, Pp 1602-1613 (2019)
ACS Central Science, Vol 5, Iss 9, Pp 1602-1613 (2019)
Rhodamine dyes exist in equilibrium between a fluorescent zwitterion and a nonfluorescent lactone. Tuning this equilibrium toward the nonfluorescent lactone form can improve cell-permeability and allow creation of “fluorogenic” compounds—ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd679cd566df1026f67b3cf1e14634ab
https://doi.org/10.1021/acscentsci.9b00676
https://doi.org/10.1021/acscentsci.9b00676
Autor:
Luke D. Lavis, Jason C. Casler, Ariana N. Tkachuk, Liangqi Xie, Jonathan B. Grimm, Heejun Choi, Benjamin S. Glick, Ronak Patel, Jennifer Lippincott-Schwartz, Timothy A. Brown, Zhe Liu
Fluorescence microscopy relies on dyes that absorb short-wavelength photons and emit longer-wavelength light. In addition to this fluorescence process, dyes can undergo other photochemical reactions that result in spectral shifts and irreversible pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40c9780690ebd1f962f213440db0879a
https://doi.org/10.1101/2020.08.17.250027
https://doi.org/10.1101/2020.08.17.250027
Autor:
Lixia Zhang, Sebastien Phan, Jonathan B. Grimm, Timothy A. Brown, Luke D. Lavis, Guillaume A. Castillon, Thomas C. Binns, Stephen R. Adams, Minoru Koyama, Ariana N. Tkachuk, Zhe Liu, Mark H. Ellisman, Anthony X. Ayala
Publikováno v:
Cell chemical biology, vol 27, iss 8
Cell Chem Biol
Cell Chem Biol
Summary Light-mediated chemical reactions are powerful methods for manipulating and interrogating biological systems. Photosensitizers, compounds that generate reactive oxygen species upon excitation with light, can be utilized for numerous biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3539767ad5e718adba19ad5d2aa492
https://escholarship.org/uc/item/79f8286g
https://escholarship.org/uc/item/79f8286g
Publikováno v:
ACS Central Science, Vol 3, Iss 9, Pp 975-985 (2017)
ACS Central Science
ACS Central Science
The century-old fluoresceins and rhodamines persist as flexible scaffolds for fluorescent and fluorogenic compounds. Extensive exploration of these xanthene dyes has yielded general structure–activity relationships where the development of new prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e5a33f84b04b0811bb777da225f950
https://doi.org/10.1021/acscentsci.7b00247
https://doi.org/10.1021/acscentsci.7b00247
Autor:
Jennifer Lippincott-Schwartz, Timothy A. Brown, Boaz Mohar, Ariana N. Tkachuk, Heejun Choi, Ronak Patel, Jonathan B. Grimm, Luke D. Lavis, Natalie Falco
Expanding the palette of fluorescent dyes is vital for pushing the frontier of biological imaging. Although rhodamine dyes remain the premier type of small-molecule fluorophore due to their bioavailability and brightness, variants excited with far-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b06f602dcae07d8bd8095abd148454a