Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ariana Gitzen"'
Publikováno v:
Viruses, Vol 10, Iss 1, p 26 (2018)
Tetherin is an interferon-inducible antiviral protein that inhibits the release of a broad spectrum of enveloped viruses by retaining virions at the surface of infected cells. While the role of specific tetherin domains in antiviral activity is clear
Externí odkaz:
https://doaj.org/article/75964787830441be98cab79ccef7cdd4
The HIV-1 accessory protein Vpu enhances virus release by down-regulating cell surface expression of the host restriction factor tetherin. To further understand the role of host proteins in Vpu function, we carried out yeast two-hybrid screening and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afe642c55b4875b5701c22680e2dc27
https://doi.org/10.1101/2020.03.01.972125
https://doi.org/10.1101/2020.03.01.972125
Publikováno v:
J Biol Chem
Host proteins with antiviral activity have evolved as first-line defenses to suppress viral replication. The HIV-1 accessory protein viral protein U (Vpu) enhances release of the virus from host cells by down-regulating the cell-surface expression of