Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ariana C. Combs"'
Autor:
Sampath K. Gollapudi, Ariana C. Combs, Stephen J. Langer, Thomas C. Irving, Srinivas Chakravarthy, Na Sa, Weikang Ma, Suman Nag
Publikováno v:
J Mol Biol
In addition to a conventional relaxed state, a fraction of myosins in the cardiac muscle exists in a newly-discovered low-energy consuming super-relaxed (SRX) state, which is kept as a reserve pool that may be engaged under sustained increased cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cb0c11dadf3843ec8e331bea830792
https://europepmc.org/articles/PMC9044501/
https://europepmc.org/articles/PMC9044501/
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004431 (2014)
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disorder caused by mutations in the dystrophin gene. To examine the influence of muscle structure on the pathogenesis of DMD we generated mdx4cv:desmin double knockout (dko) mice. The dko m
Externí odkaz:
https://doaj.org/article/b5ea6b9ead3d43d9b81617310c1deae7
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff378c039bc0265b651204921cb5c165
https://doi.org/10.1096/fasebj.2020.34.s1.09807
https://doi.org/10.1096/fasebj.2020.34.s1.09807
Autor:
Leslie A. Leinwand, Stephen J. Langer, Carlos Vera, Marieke J. Bloemink, Michael A. Geeves, John C. Deacon, Ariana C. Combs
Publikováno v:
The Journal of Biological Chemistry
Background: R453C is a mutation in human cardiac myosin and is associated with a high incidence of sudden cardiac death. Results: R453C alters few kinetic parameters, except for the conformational changes associated with ATP binding and hydrolysis. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48428721265a441fdbd11994920bb00c
http://europepmc.org/articles/PMC3931073
http://europepmc.org/articles/PMC3931073
Autor:
Zoltan Ujfalusi, Shirley Sutton, Suman Nag, Stephen J. Langer, Leslie A. Leinwand, Kathleen M. Ruppel, Ruth F. Sommese, Ariana C. Combs, James A. Spudich, Michael A. Geeves
Publikováno v:
Science Advances
Force parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of molecular motor function.
Hypertrophic cardiomyopathy (HCM) is the most frequently occurring inherited cardiovascular disease. It is cau
Hypertrophic cardiomyopathy (HCM) is the most frequently occurring inherited cardiovascular disease. It is cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c145b55977a3f4ed6a114a47b21a758
https://doi.org/10.1126/sciadv.1500511
https://doi.org/10.1126/sciadv.1500511
Autor:
Kiyotoshi Sekiguchi, James M. Ervasti, Ryoko Nishiuchi, Yoshinao Wada, Sugiko Futaki, Yoshitaka Hayashi, Shaoliang Li, Hiroyuki Ido, Ariana C. Combs, Kenji Harada, Yuko Natsuka
Publikováno v:
Journal of Biological Chemistry. 279(12):10946-10954
This research was originally published in the Journal of Biological Chemistry. Hiroyuki Ido, Kenji Harada, Sugiko Futaki, Yoshitaka Hayashi, Ryoko Nishiuchi, Yuko Natsuka, Shaoliang Li, Yoshinao Wada, Ariana C. Combs, James M. Ervasti and Kiyotoshi S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c309e576578d24a8c3208429d35f4b0e
https://hdl.handle.net/11094/71431
https://hdl.handle.net/11094/71431
Publikováno v:
Journal of Biological Chemistry. 278:44868-44873
Although unique O-linked oligosaccharides on alpha-dystroglycan are important for binding to a variety of extracellular ligands, the function(s) of more generic carbohydrate structures on alpha-dystroglycan remain unclear. Recent studies suggest a ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2320e398877746dc07b7458857491ab
https://doi.org/10.1074/jbc.m307026200
https://doi.org/10.1074/jbc.m307026200
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 10, Iss 6, p e1004431 (2014)
PLoS Genetics, Vol 10, Iss 6, p e1004431 (2014)
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disorder caused by mutations in the dystrophin gene. To examine the influence of muscle structure on the pathogenesis of DMD we generated mdx4cv:desmin double knockout (dko) mice. The dko m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6082d5027ce4d26fe592e9843b173fd1
http://europepmc.org/articles/PMC4055409
http://europepmc.org/articles/PMC4055409
Publikováno v:
Muscle & Nerve. 42:268-270
Currently available polymerase chain reaction (PCR) genotyping methods for point mutations in the mouse dystrophin gene can lead to false positives and result in wasted time and money due to breeding or treating the wrong mice. Here we describe a sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5167f2446b56518df7bc8e438955c08e
https://doi.org/10.1002/mus.21700
https://doi.org/10.1002/mus.21700
Autor:
Annie L. Burwell, James M. Ervasti, Matthew T. Sdano, Ariana C. Combs, Erin L. McDearmon, Brian A. Renley
Publikováno v:
Journal of Biological Chemistry. 273:24139-24144
The alpha-dystroglycan binding properties of laminins extracted from fully differentiated skeletal muscle were characterized. We observed that the laminins expressed predominantly in normal adult rat or mouse skeletal muscle bound alpha-dystroglycan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d29efde59eeedaaa0a33fefdc0f15e4
https://doi.org/10.1074/jbc.273.37.24139
https://doi.org/10.1074/jbc.273.37.24139