Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Arian Emami Riedmaier"'
Autor:
Abdullah Al Shoyaib, Arian Emami Riedmaier, Anita Kumar, Partha Roy, Neil John Parrott, Lanyan Fang, Nilufer Tampal, Yuching Yang, Rebeka Jereb, Liang Zhao, Fang Wu
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 5, Pp 610-618 (2023)
Abstract This workshop report summarizes the presentations and panel discussion related to the use of physiologically based pharmacokinetic (PBPK) modeling approaches for food effect assessment, collected from Session 2 of Day 2 of the workshop title
Externí odkaz:
https://doaj.org/article/fc0a03feb23a426592eb8c8e2923117e
Autor:
Tamara D. Cabalu, Mengyao Li, Kenichi Umehara, Dermot F. McGinnity, Neil Parrott, Kunal S Taskar, Arian Emami Riedmaier, Micaela B Reddy, Hugues Chanteux, Martin E. Dowty, Justine Badée, Jialin Mao, Jayaprakasam Bolleddula, Loeckie de Zwart, Jessica Rehmel, Dwaipayan Mukherjee, Chandra Prakash, Niresh Hariparsad, Masakatsu Kotsuma, Diane Ramsden, Karthik Venkatakrishnan, Venkatesh Pilla Reddy, Kushal Shah
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:770-781
The International Consortium for Innovation and Quality (IQ) Physiologically Based Pharmacokinetic (PBPK) Modeling Induction Working Group (IWG) conducted a survey across participating companies around general strategies for PBPK modeling of inductio
Autor:
Abdullah Al Shoyaib, Arian Emami Riedmaier, Anita Kumar, Partha Roy, Neil John Parrott, Lanyan Fang, Nilufer Tampal, Yuching Yang, Rebeka Jereb, Liang Zhao, Fang Wu
Publikováno v:
CPT: pharmacometricssystems pharmacology.
This workshop report summarizes the presentations and panel discussion related to the utilization of physiologically based pharmacokinetic (PBPK) modeling approaches for food effect assessment, collected from session-2 of day-2 of the workshop titled
Autor:
Carl Petersson, Xin Zhou, Joerg Berghausen, David Cebrian, Michael Davies, Kevin DeMent, Peter Eddershaw, Arian Emami Riedmaier, Alix F. Leblanc, Nenad Manveski, Punit Marathe, Panteleimon D. Mavroudis, Robin McDougall, Neil Parrott, Andreas Reichel, Charles Rotter, David Tess, Laurie P. Volak, Guangqing Xiao, Zheng Yang, James Baker
Publikováno v:
The AAPS journal. 24(5)
Accurate prediction of human clearance (CL) and volume of distribution at steady state (V
Autor:
Arian Emami Riedmaier
Publikováno v:
The AAPS journal. 24(1)
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2342
In this chapter, we illustrate the criticality of proper fitting of enzyme kinetic data. Simple techniques are provided to arrive at meaningful kinetic parameters, illustrated using an example, nonmonotonic data set. In the initial analysis of this d
Publikováno v:
The AAPS Journal. 23
Food can alter drug absorption and impact safety and efficacy. Besides conducting clinical studies, in vitro approaches such as biorelevant solubility and dissolution testing and in vivo dog studies are typical approaches to estimate a drug's food ef
Autor:
Ryota Kikuchi, Sonia M. de Morais, Gary J. Jenkins, Kenneth R. Durbin, Junli Ma, William J. Chiou, Daniel A.J. Bow, John P. Savaryn, Arian Emami Riedmaier
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 49(10)
The successful prospective incorporation of in vitro transporter kinetics in physiologically based pharmacokinetic (PBPK) models to describe drug disposition remains challenging. Although determination of scaling factors to extrapolate in vitro to in
Autor:
Arian Emami Riedmaier, James Huckle, Xavier Pepin, Sumit Basu, Neil Parrott, Ravindra V Alluri, Stephanie Kay Dodd
Publikováno v:
The AAPS Journal. 23
Over the last 10 years, 40% of approved oral drugs exhibited a significant effect of food on their pharmacokinetics (PK) and currently the only method to characterize the effect of food on drug absorption, which is recognized by the authorities, is t
Publikováno v:
Methods in Molecular Biology ISBN: 9781071615539
In this chapter, we illustrate the criticality of proper fitting of enzyme kinetic data. Simple techniques are provided to arrive at meaningful kinetic parameters, illustrated using an example, nonmonotonic data set. In the initial analysis of this d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d88d694b36a403942a69b1de3621e3
https://doi.org/10.1007/978-1-0716-1554-6_22
https://doi.org/10.1007/978-1-0716-1554-6_22