The PTP1B inhibitor MSI-1436 ameliorates liver insulin sensitivity by modulating autophagy, ER stress and systemic inflammation in Equine metabolic syndrome affected horses

Autor: Lynda Bourebaba, Anna Serwotka-Suszczak, Ariadna Pielok, Mateusz Sikora, Malwina Mularczyk, Krzysztof Marycz

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

BackgroundEquine metabolic syndrome (EMS) is a multifactorial pathology gathering insulin resistance, low-grade inflammation and past or chronic laminitis. Among the several molecular mechanisms underlying EMS pathogenesis, increased negative insulin

Externí odkaz: https://doaj.org/article/b0ddfba5c9ad4e7da57061e1fef30372

The Role of miR-21 in Osteoblasts–Osteoclasts Coupling In Vitro

Autor: Agnieszka Smieszek, Klaudia Marcinkowska, Ariadna Pielok, Mateusz Sikora, Lukas Valihrach, Krzysztof Marycz

Publikováno v: Cells, Vol 9, Iss 2, p 479 (2020)

MiR-21 is being gradually more and more recognized as a molecule regulating bone tissue homeostasis. However, its function is not fully understood due to the dual role of miR-21 on bone-forming and bone-resorbing cells. In this study, we investigated

Externí odkaz: https://doaj.org/article/8a2a4bcf1a8641e8a5e8a8f9a107b3a1

Zirconium Oxide Thin Films Obtained by Atomic Layer Deposition Technology Abolish the Anti-Osteogenic Effect Resulting from miR-21 Inhibition in the Pre-Osteoblastic MC3T3 Cell Line

Autor: Klaudia Marcinkowska, Agnieszka Smieszek, Mateusz Sikora, Aleksandra Seweryn, Bartlomiej S. Witkowski, Marek Godlewski, Krzysztof Marycz, Ariadna Pielok, Krystyna Lawniczak-Jablonska, R. Pietruszka

Publikováno v: International Journal of Nanomedicine

Aleksandra Seweryn,1 Ariadna Pielok,2 Krystyna Lawniczak-Jablonska,1 Rafal Pietruszka,1 Klaudia Marcinkowska,2 Mateusz Sikora,2 Bartlomiej S Witkowski,1 Marek Godlewski,1 Krzysztof Marycz,2,3 Agnieszka Smieszek2 1Institute of Physics, Polish Academy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f6fb6fd91720a6b7fdf0ca3b734d65
http://europepmc.org/articles/PMC7069564

Novel Nanohydroxyapatite (nHAp)-Based Scaffold Doped with Iron Oxide Nanoparticles (IO), Functionalized with Small Non-Coding RNA (miR-21/124) Modulates Expression of Runt-Related Transcriptional Factor 2 and Osteopontin, Promoting Regeneration of Osteoporotic Bone in Bilateral Cranial Defects in a Senescence-Accelerated Mouse Model (SAM/P6). PART 2

Autor: Jarosław Filipiak, Katarzyna Kornicka-Garbowska, Anna Lipińska, Anna Nikodem, Rafal J. Wiglusz, Maciej Janeczek, Agnieszka Śmieszek, Krzysztof Marycz, Paulina Sobierajska, Jean-Marie Nedelec, Ariadna Pielok

Publikováno v: International Journal of Nanomedicine
International Journal of Nanomedicine, 2021, 16, pp.6049-6065. ⟨10.2147/IJN.S316240⟩
International Journal of Nanomedicine, Dove Medical Press, 2021, 16, pp.6049-6065. ⟨10.2147/IJN.S316240⟩

Krzysztof Marycz,1,2 Agnieszka Śmieszek,1 Katarzyna Kornicka-Garbowska,1,2 Ariadna Pielok,1 Maciej Janeczek,3 Anna Lipińska,3 Anna Nikodem,4 Jarosław Filipiak,4 Paulina Sobierajska,5 Jean-Marie Nedelec,6 Rafał J Wiglusz2,5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a82f7b9001ad151f21188d43ebdbe6
https://uca.hal.science/hal-03468967

The Role of miR-21 in Osteoblasts–Osteoclasts Coupling In Vitro

Autor: Lukas Valihrach, Agnieszka Smieszek, Krzysztof Marycz, Klaudia Marcinkowska, Ariadna Pielok, Mateusz Sikora

Publikováno v: Cells, Vol 9, Iss 2, p 479 (2020)
Cells
Volume 9
Issue 2

MiR-21 is being gradually more and more recognized as a molecule regulating bone tissue homeostasis. However, its function is not fully understood due to the dual role of miR-21 on bone-forming and bone-resorbing cells. In this study, we investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04528e94826312a99073d162c16402d
https://doi.org/10.3390/cells9020479