Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ariadna Fernández-Calvet"'
Autor:
Cristina Herencias, Laura Álvaro-Llorente, Paula Ramiro-Martínez, Ariadna Fernández-Calvet, Ada Muñoz-Cazalla, Javier DelaFuente, Fabrice E. Graf, Laura Jaraba-Soto, Juan Antonio Castillo-Polo, Rafael Cantón, Álvaro San Millán, Jerónimo Rodríguez-Beltrán
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Major antibiotic groups are losing effectiveness due to the uncontrollable spread of antimicrobial resistance (AMR) genes. Among these, β-lactam resistance genes –encoding β-lactamases– stand as the most common resistance mechanism in
Externí odkaz:
https://doaj.org/article/4459ee25c64b452a9a925117443935ea
Autor:
Ariadna Fernández-Calvet, Leticia Matilla-Cuenca, María Izco, Susanna Navarro, Miriam Serrano, Salvador Ventura, Javier Blesa, Maite Herráiz, Gorka Alkorta-Aranburu, Sergio Galera, Igor Ruiz de los Mozos, María Luisa Mansego, Alejandro Toledo-Arana, Lydia Alvarez-Erviti, Jaione Valle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Age-related neurodegenerative diseases involving amyloid aggregation remain one of the biggest challenges of modern medicine. Alterations in the gastrointestinal microbiome play an active role in the aetiology of neurological disorders. Here
Externí odkaz:
https://doaj.org/article/40b541987ebf412386b91ac11bd1521e
Autor:
Celia Gil-Campillo, Aida González-Díaz, Beatriz Rapún-Araiz, Oihane Iriarte-Elizaintzin, Iris Elizalde-Gutiérrez, Ariadna Fernández-Calvet, María Lázaro-Díez, Sara Martí, Junkal Garmendia
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Antibiotic resistance is a major Public Health challenge worldwide. Mechanisms other than resistance are described as contributors to therapeutic failure. These include heteroresistance and tolerance, which escape the standardized procedures used for
Externí odkaz:
https://doaj.org/article/ae0b07c790cc4c588cfceb38de7f47cb
Autor:
Beatriz Rapún-Araiz, Ioritz Sorzabal-Bellido, Javier Asensio-López, María Lázaro-Díez, Mikel Ariz, Carlos Sobejano de la Merced, Begoña Euba, Ariadna Fernández-Calvet, Ivan Cortés-Domínguez, Saioa Burgui, Alejandro Toledo-Arana, Carlos Ortiz-de-Solórzano, Junkal Garmendia
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Standardized clinical procedures for antibiotic administration rely on pathogen identification and antibiotic susceptibility testing, often performed on single-colony bacterial isolates. For respiratory pathogens, this could be questionable,
Externí odkaz:
https://doaj.org/article/536def903f3f46f69c4c1b97b267de0b
Autor:
Ariadna Fernández-Calvet, Begoña Euba, Celia Gil-Campillo, Arancha Catalan-Moreno, Javier Moleres, Sara Martí, Alexandra Merlos, Jeroen D. Langereis, Francisco García-del Portillo, Lauren O. Bakaletz, Garth D. Ehrlich, Eric A. Porsch, Margarita Menéndez, Joshua C. Mell, Alejandro Toledo-Arana, Junkal Garmendia
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Human-adapted bacterial pathogens have evolved specific mechanisms to colonize their host niche. Phase variation is a contingency strategy to allow adaptation to changing conditions, as phase-variable bacterial loci rapidly and reversibly switch thei
Externí odkaz:
https://doaj.org/article/07720d572d9e49e499e710710932f33f
Autor:
Irene Rodríguez-Arce, Tamim Al-Jubair, Begoña Euba, Ariadna Fernández-Calvet, Celia Gil-Campillo, Sara Martí, Susanna Törnroth-Horsefield, Kristian Riesbeck, Junkal Garmendia
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 315-333 (2019)
Nutrient iron sequestration is the most significant form of nutritional immunity and causes bacterial pathogens to evolve strategies of host iron scavenging. Cigarette smoking contains iron particulates altering lung and systemic iron homeostasis, wh
Externí odkaz:
https://doaj.org/article/158b0dc770704a5fa4a7a2fc9f841531
Autor:
Ariadna Fernández-Calvet, Irene Rodríguez-Arce, Goizeder Almagro, Javier Moleres, Begoña Euba, Lucía Caballero, Sara Martí, José Ramos-Vivas, Toby Leigh Bartholomew, Xabier Morales, Carlos Ortíz-de-Solórzano, José Enrique Yuste, José Antonio Bengoechea, Raquel Conde-Álvarez, Junkal Garmendia
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation. Lipids are key inflammatory mediators in these disease conditi
Externí odkaz:
https://doaj.org/article/305eb8a34c7740f6a4bd2c713047f4de
Autor:
Javier Moleres, Ariadna Fernández-Calvet, Rachel L. Ehrlich, Sara Martí, Lucía Pérez-Regidor, Begoña Euba, Irene Rodríguez-Arce, Sergey Balashov, Ester Cuevas, Josefina Liñares, Carmen Ardanuy, Sonsoles Martín-Santamaría, Garth D. Ehrlich, Joshua Chang Mell, Junkal Garmendia
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Tracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen nontypeable Haemophilus influenzae (NTHi) infects the lower airway
Externí odkaz:
https://doaj.org/article/cb2d1564d60c4e4f982642d3ba3cf375
Autor:
Irene Rodríguez-Arce, Sara Martí, Begoña Euba, Ariadna Fernández-Calvet, Javier Moleres, Nahikari López-López, Montserrat Barberán, José Ramos-Vivas, Fe Tubau, Carmen Losa, Carmen Ardanuy, José Leiva, José E. Yuste, Junkal Garmendia
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Antibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate synthase gene thyA, which can
Externí odkaz:
https://doaj.org/article/e4236df261aa49c5b2ad9f07ddf1cce1
Autor:
Joshua Chang Mell, Cristina Viadas, Javier Moleres, Sunita Sinha, Ariadna Fernández-Calvet, Eric A Porsch, Joseph W St Geme, Corey Nislow, Rosemary J Redfield, Junkal Garmendia
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005576 (2016)
Many bacterial species actively take up and recombine homologous DNA into their genomes, called natural competence, a trait that offers a means to identify the genetic basis of naturally occurring phenotypic variation. Here, we describe "transformed
Externí odkaz:
https://doaj.org/article/ff5422b7ba7b420cb2655bffa7f16064