Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Aria Tzika, A."'
Autor:
Arijit Chakraborty, Arunava Bandyopadhaya, Vijay K Singh, Filip Kovacic, Sujin Cha, William M Oldham, A Aria Tzika, Laurence G Rahme
Publikováno v:
eLife, Vol 13 (2024)
How bacterial pathogens exploit host metabolism to promote immune tolerance and persist in infected hosts remains elusive. To achieve this, we show that Pseudomonas aeruginosa (PA), a recalcitrant pathogen, utilizes the quorum sensing (QS) signal 2
Externí odkaz:
https://doaj.org/article/d545ff885eb5410092dedd196b9b7566
Autor:
Shifu Aggarwal, Vijay Singh, Arijit Chakraborty, Sujin Cha, Alexandra Dimitriou, Claire de Crescenzo, Olivia Izikson, Lucy Yu, Roberto Plebani, A. Aria Tzika, Laurence G. Rahme
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Sepsis and chronic infections with Pseudomonas aeruginosa, a leading “ESKAPE” bacterial pathogen, are associated with increased morbidity and mortality and skeletal muscle atrophy. The actions of this pathogen on skeletal muscle remain p
Externí odkaz:
https://doaj.org/article/bf0916bbb6394aaf9f6be9c78ab04a86
Autor:
Loukas G. Astrakas, Sabrina Elbach, Irini Giannopulu, Shasha Li, Howard Benjafield, A. Aria Tzika
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionThe acknowledged role of external rewards in chronic stroke rehabilitation, offering positive reinforcement and motivation, has significantly contributed to patient engagement and perseverance. However, the exploration of self-reward’s
Externí odkaz:
https://doaj.org/article/e9938aa57daa4ff7b0bad082bbaad05b
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Although the relationship between corticospinal tract (CST) fiber degeneration and motor outcome after stroke has been established, the relationship of sensorimotor cortical areas with CST fibers has not been clarified. Also limited research has been
Externí odkaz:
https://doaj.org/article/ac7a78305e5943f18363665d58f2c9a0
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/bf6439a1da924a63997d148098f69088
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Skeletal muscle function is compromised in many illnesses, including chronic infections. The Pseudomonas aeruginosa quorum sensing (QS) signal, 2-amino acetophenone (2-AA), is produced during acute and chronic infections and excreted in huma
Externí odkaz:
https://doaj.org/article/02d2ba407b644df7a904224037bfff90
Autor:
Michael A. Moskowitz, A. Aria Tzika, Loukas G. Astrakas, Mark P. Ottensmeyer, Christian Pusatere, Shasha Li
Publikováno v:
The open neuroimaging journal
Background: Ischemic stroke is the most common cause of complex chronic disability and the third leading cause of death worldwide. In recovering stroke patients, peak activation within the ipsilesional primary motor cortex (M1) during the performance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e836db3c4e71c0dfd73669f468e7ba52
https://doi.org/10.2174/1874440002114010008
https://doi.org/10.2174/1874440002114010008
Macrophages utilize metabolic pathways to generate energy and metabolites that may be vulnerable to pathogen hijacking to favor pathogen survival and persistence. It is unclear how bacterial pathogens alter metabolic pathways in immune cells for thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd3a3f2a22a07cdeec51a6152ced5dc
https://doi.org/10.1101/2021.10.03.462785
https://doi.org/10.1101/2021.10.03.462785
Autor:
Biliana Lesic, François Lépine, Eric Déziel, Jiangwen Zhang, Qunhao Zhang, Katie Padfield, Marie-Hélène Castonguay, Sylvain Milot, Scott Stachel, A Aria Tzika, Ronald G Tompkins, Laurence G Rahme
Publikováno v:
PLoS Pathogens, Vol 3, Iss 9, Pp 1229-1239 (2007)
Long-term antibiotic use generates pan-resistant super pathogens. Anti-infective compounds that selectively disrupt virulence pathways without affecting cell viability may be used to efficiently combat infections caused by these pathogens. A candidat
Externí odkaz:
https://doaj.org/article/e152aa1dae1e4fd2921f7f4e7f1f8b39
Autor:
Melissa Starkey, Francois Lepine, Damien Maura, Arunava Bandyopadhaya, Biljana Lesic, Jianxin He, Tomoe Kitao, Valeria Righi, Sylvain Milot, Aria Tzika, Laurence Rahme
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004321 (2014)
Etiological agents of acute, persistent, or relapsing clinical infections are often refractory to antibiotics due to multidrug resistance and/or antibiotic tolerance. Pseudomonas aeruginosa is an opportunistic Gram-negative bacterial pathogen that ca
Externí odkaz:
https://doaj.org/article/9aa02961081547b7bbda3bdbbafe6365