Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ari-Pekka Kvist"'
Autor:
Heli Ruotsalainen, Maija Risteli, Chunguang Wang, Yu Wang, Marjo Karppinen, Ulrich Bergmann, Ari-Pekka Kvist, Helmut Pospiech, Karl-Heinz Herzig, Raili Myllylä
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50045 (2012)
Lysyl hydroxylase 3 (LH3) has lysyl hydroxylase, galactosyltransferase, and glucosyltransferase activities, which are sequentially required for the formation of glucosylgalactosyl hydroxylysines in collagens. Here we demonstrate for the first time th
Externí odkaz:
https://doaj.org/article/3d6dae95d98c4674a8ba694f1b1b2bd0
Autor:
Ari-Pekka Kvist, J. Kalervo Hiltunen, Kaija J. Autio, Werner Schmitz, Markku J. Savolainen, Matti Jauhiainen, Stefan E.H. Alexson, Päivi Pirilä, Tiina Kotti, Tuire Salonurmi, Eija M. Selkälä, Ernst Conzelmann, Sanna Kuusisto
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:1335-1343
Bile acids play multiple roles in the physiology of vertebrates; they facilitate lipid absorption, serve as signaling molecules to control carbohydrate and lipid metabolism, and provide a disposal route for cholesterol. Unexpectedly, the α-methylacy
Autor:
J. Kalervo Hiltunen, Ari-Pekka Kvist, Remya R. Nair, Werner Schmitz, Kaija J. Autio, Myriam Baes, Eija M. Selkälä
Publikováno v:
Biochimica et biophysica acta. 1851(10)
α-Methylacyl-CoA racemase (Amacr) catalyzes the racemization of the 25-methyl group in C27-intermediates in bile acid synthesis and in methyl-branched fatty acids such as pristanic acid, a metabolite derived from phytol. Consequently, patients with
Autor:
Kati Rautavuoma, Johanna Myllyharju, Asta Pirskanen, Kaisa Passoja, Kati Takaluoma, Ari-Pekka Kvist, Kari I. Kivirikko
Publikováno v:
Journal of Biological Chemistry. 277:23084-23091
Lysyl hydroxylase (LH) catalyzes the formation of hydroxylysine in collagens; three human isoenzymes have been cloned so far. We report here on the purification of all three recombinant isoenzymes to homogeneity from the medium of cultured insect cel
Autor:
Lauri Eklund, Timo Väisänen, Raija Sormunen, Malin Sund, Reinhard Fässler, Pasi Hägg, Ari-Pekka Kvist, Anne Latvanlehto, Taina Pihlajaniemi, Jyrki Komulainen
Publikováno v:
The American Journal of Pathology. 159:1581-1592
Type XIII collagen is a type II transmembrane protein found at many sites of cell adhesion in tissues. Homologous recombination was used to generate a transgenic mouse line (Col13a1(N/N)) that expresses N-terminally altered type XIII collagen molecul
Autor:
Anne Tuomisto, Riikka Ylönen, Malin Sund, Taina Pihlajaniemi, Ari-Pekka Kvist, Jenni Tahkola, Raija Sormunen, Sirpa Kontusaari, Helena Autio-Harmainen
Publikováno v:
The EMBO Journal. 20:5153-5164
Type XIII collagen is a type II transmembrane protein found at sites of cell adhesion. Transgenic mouse lines were generated by microinjection of a DNA construct directing the synthesis of truncated alpha1(XIII) chains. Shortened alpha 1(XIII) chains
Autor:
Biagio Saitta, Paolo Bonaldo, Iiro Eerola, Marko Rehn, Taina Pihlajaniemi, Eero Vuorio, R Sallinen, Anne Latvanlehto, Nina Horelli-Kuitunen, Maija Wessman, Giorgio M. Bressan, Ari-Pekka Kvist, Aarno Palotie, Mon-Li Chu
Publikováno v:
Mammalian Genome. 12:340-346
Fluorescence in situ hybridization (FISH) on mechanically stretched chromosomes (MSCs) and extended DNA fibers enables construction of high-resolution physical maps by accurate ordering and orienting genomic clones as well as by measuring physical le
Autor:
Taina Pihlajaniemi, Nina Horelli-Kuitunen, Ari-Pekka Kvist, Tarja Helaakoski, Aarno Palotie, Kari I. Kivirikko
Publikováno v:
Genomics. 46:299-302
The genes for type XIII collagen (COL13A1) and prolyl 4-hydroxylase (P4HA) were previously assigned to human chromosome 10q by radioactive in situ hybridization. Here we have applied fluorescence in situ hybridization combined with targets representi
Autor:
J K Hiltunen, K M Siivari, Ari-Pekka Kvist, Yong-Mei Qin, H M Helander, Matti Poutanen, Ulf Hellman, W Schmitz, Ernst Conzelmann
Publikováno v:
Biochemical Journal. 321:21-28
In the present study we have cloned and characterized a novel rat peroxisomal multifunctional enzyme (MFE) named perMFE-II. The purified 2-enoyl-CoA hydratase 2 with an Mr of 31500 from rat liver [Malila, Siivari, Mäkelä, Jalonen, Latipää, Kunau
Autor:
Karl-Heinz Herzig, Yu Wang, Chunguang Wang, Ulrich Bergmann, Heli Ruotsalainen, Ari-Pekka Kvist, Helmut Pospiech, Marjo Karppinen, Raili Myllylä, Maija Risteli
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e50045 (2012)
PLoS ONE, Vol 7, Iss 11, p e50045 (2012)
Lysyl hydroxylase 3 (LH3) has lysyl hydroxylase, galactosyltransferase, and glucosyltransferase activities, which are sequentially required for the formation of glucosylgalactosyl hydroxylysines in collagens. Here we demonstrate for the first time th