Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ari Karjalainen"'
Publikováno v:
Cellular Physiology and Biochemistry. 14:143-154
The pathways for the efflux of K(+) from osmotically-swollen HTC rat hepatoma cells were investigated using (86)Rb(+) as a tracer for K(+). Exposure of HTC cells to a hypotonic solution ( 20 min. The second (86)Rb(+) efflux component was not inhibite
Publikováno v:
Biochemical Journal. 342:49-56
Ascorbate (AH, the reduced form of vitamin C) is an important radical scavenger and antioxidant in human plasma; the resulting ascorbyl radical can disproportionate to AH and dehydroascorbic acid (DHA). Here we address potential maintenance mechanism
Publikováno v:
IUBMB Life. 44:127-134
The effect of alpha-lipoate and dihydrolipoate on the mitochondrial permeability transition was investigated. Both substances promoted the permeability transition in isolated rat liver mitochondria and in permeabilized hepatocytes, dihydrolipoate mos
Publikováno v:
Biochemical Journal. 323:463-467
Glucagon induces a slight Ca2+ efflux when administered to the perfused rat liver. However, the hormone promotes rapid and significant Ca2+ influx after the prior administration of 2,5-di(t-butyl)-1,4-hydroquinone (BHQ), an agent that promotes Ca2+ r
Autor:
Fyfe L. Bygrave, Ari Karjalainen
Publikováno v:
Cell Calcium. 18:214-222
Influx of Ca2+ induced by the synergistic action of glucagon plus vasopressin in the perfused rat liver was progressively inhibited by infusing increasing concentrations of Ni2+ to the perfusion medium. The onset of Ca2+ influx following vasopressin
Publikováno v:
Hepatology. 21:1455-1464
The actions of vasopressin and glucagon, administered alone or together, were assessed on bile flow in perfused livers from rats made cholestatic by the injection of ethynylestradiol and from those allowed to recover from such treatment. Concomitant
Autor:
Ari Karjalainen, Fyfe L. Bygrave
Publikováno v:
Biochemical Journal. 301:187-192
A study was made of the initial responses of perfusate Ca2+ fluxes and bile flow to Ca(2+)-mobilizing agonists, following refinements to the methods for analysing these parameters in the perfused rat liver. Net Ca2+ efflux induced by vasopressin comm
Publikováno v:
Cellular Signalling. 6:1-9
The flow of bile is subject to short-term modulation by glucagon and calcium-mobilizing hormones. Of potential relevance is the crosstalk between the second messenger-mediated signal transducing systems of these agonists. This latter point has reveal
Publikováno v:
The Journal of biological chemistry. 277(43)
Exposure of HTC rat hepatoma cells to a 33% decrease in extracellular osmolality caused the cytosolic Ca(2+) concentration ([Ca(2+)](i)) to increase transiently by approximately 90 nm. This rise in [Ca(2+)](i) was inhibited strongly by apyrase, grade
Publikováno v:
The Biochemical journal. 330
Treatment of perfused rat liver with the nitric oxide-generating reagent molsidomine led to substantial increases in cGMP without itself affecting basal Ca2+ fluxes. Under these conditions the ability of glucagon plus vasopressin to induce Ca2+ influ