Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ari Jon Arason"'
Autor:
Ari Jon Arason, Jon Petur Joelsson, Bryndis Valdimarsdottir, Snaevar Sigurdsson, Alexander Gudjonsson, Skarphedinn Halldorsson, Freyr Johannsson, Ottar Rolfsson, Fredrik Lehmann, Saevar Ingthorsson, Paulina Cherek, Gudmundur H. Gudmundsson, Fridrik R. Gardarsson, Clive P. Page, Olafur Baldursson, Thorarinn Gudjonsson, Jennifer A. Kricker
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Azithromycin (Azm) is a macrolide recognized for its disease-modifying effects and reduction in exacerbation of chronic airway diseases. It is not clear whether the beneficial effects of Azm are due to its anti-microbial activity
Externí odkaz:
https://doaj.org/article/c8da4be92fa246189c8660fe3fd024d1
Autor:
Ari Jon Arason, Hulda R Jonsdottir, Skarphedinn Halldorsson, Berglind Eva Benediktsdottir, Jon Thor Bergthorsson, Saevar Ingthorsson, Olafur Baldursson, Satrajit Sinha, Thorarinn Gudjonsson, Magnus K Magnusson
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88683 (2014)
The upper airways are lined with a pseudostratified bronchial epithelium that forms a barrier against unwanted substances in breathing air. The transcription factor p63, which is important for stratification of skin epithelium, has been shown to be e
Externí odkaz:
https://doaj.org/article/7ee2d0d85e3c4f28814a8743b7be37bd
Autor:
Valgardur Sigurdsson, Saevar Ingthorsson, Bylgja Hilmarsdottir, Sigrun M Gustafsdottir, Sigridur Rut Franzdottir, Ari Jon Arason, Eirikur Steingrimsson, Magnus K Magnusson, Thorarinn Gudjonsson
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60798 (2013)
Branching morphogenesis is a mechanism used by many species for organogenesis and tissue maintenance. Receptor tyrosine kinases (RTKs), including epidermal growth factor receptor (EGFR) and the sprouty protein family are believed to be critical regul
Externí odkaz:
https://doaj.org/article/7a8e2ff643864228badca2336c49eecb
Autor:
Bryndis Valdimarsdottir, Saevar Ingthorsson, Jennifer A. Kricker, Ari Jon Arason, Snaevar Sigurdsson, Fridrik Runar Gardarsson, Clive P. Page, Thorarinn Gudjonsson, Jon Petur Joelsson, Fredrik Lehmann
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Respiratory Research
Respiratory Research
Publisher's version (útgefin grein)
Background: The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung disease
Background: The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d3a5d99c35e7af91f1c4bed124a8b1
http://link.springer.com/article/10.1186/s12931-020-01489-8
http://link.springer.com/article/10.1186/s12931-020-01489-8
Autor:
Fredrik Lehmann, Jennifer A. Kricker, Clive P. Page, Fridrik Runar Gardarsson, Ari Jon Arason, Jon Petur Joelsson, Thorarinn Gudjonsson, Bryndis Valdimarsdottir, Saevar Ingthorsson
Publikováno v:
Airway pharmacology and treatment.
Azithromycin (AZM) is a macrolide which is effective in the treatment of several airway diseases induced by bacterial or environmental insults. We have previously shown barrier enhancing effects of AZM on airway epithelium (AE). In order to analyze b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448bd7fb899d0987ede9330dd7e3cd61
https://doi.org/10.1183/13993003.congress-2020.4782
https://doi.org/10.1183/13993003.congress-2020.4782
Autor:
Olafur A. Stefansson, Amaranta U. Armesto-Jimenez, Magnus K. Magnusson, Gunnar Gudmundsson, Ari Jon Arason, Thorarinn Gudjonsson
Idiopathic pulmonary fibrosis is a progressive and fatal lung disease of unknown aetiology. The strongest genetic risk factor associated with IPF development is a MUC5B promoter polymorphism (rs35705950). However, the mechanism underlying its effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf8bb4485f278a05519c0cd1eca4225
https://doi.org/10.1101/2019.12.18.880674
https://doi.org/10.1101/2019.12.18.880674
Autor:
Maria Lie Lotsberg, Camilla Krakstad, Kirstine Jacobsen, Jean Paul Thiery, Agnete S.T. Engelsen, Charlotte Kindt, Fredrik Hoel, Henrik J. Ditzel, Per Eystein Lønning, Stian Knappskog, James B. Lorens, Gro V. Røsland, Reham Helwa, Sissel E. Dyrstad, Karl Johan Tronstad, Tuan Zea Tan, Anna Berg, Deusdedit Tusubira, Ina Katrine Nitschke Pettersen, Ari Jon Arason
Publikováno v:
Cancer & Metabolism
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-18 (2019)
Røsland, G V, Dyrstad, S E, Tusubira, D, Helwa, R, Tan, T Z, Lotsberg, M L, Pettersen, I K N, Berg, A, Kindt, C, Hoel, F, Jacobsen, K, Arason, A J, Engelsen, A S T, Ditzel, H J, Lønning, P E, Krakstad, C, Thiery, J P, Lorens, J B, Knappskog, S & Tronstad, K J 2019, ' Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC ', Cancer & Metabolism, vol. 7, 6 . https://doi.org/10.1186/s40170-019-0197-8
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-18 (2019)
Røsland, G V, Dyrstad, S E, Tusubira, D, Helwa, R, Tan, T Z, Lotsberg, M L, Pettersen, I K N, Berg, A, Kindt, C, Hoel, F, Jacobsen, K, Arason, A J, Engelsen, A S T, Ditzel, H J, Lønning, P E, Krakstad, C, Thiery, J P, Lorens, J B, Knappskog, S & Tronstad, K J 2019, ' Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC ', Cancer & Metabolism, vol. 7, 6 . https://doi.org/10.1186/s40170-019-0197-8
Background Epithelial to mesenchymal transition (EMT) is a well-characterized process of cell plasticity that may involve metabolic rewiring. In cancer, EMT is associated with malignant progression, tumor heterogeneity, and therapy resistance. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb060698de7789f756861ea56de05ed9
https://doi.org/10.1186/s40170-019-0197-8
https://doi.org/10.1186/s40170-019-0197-8
Autor:
Saevar Ingthorsson, Paulina Cherek, Iwona T Myszor, Gabriel S Windels, Sigurbergur Karason, Kristjan Leosson, Ari Jon Arason, Thorarinn Gudjonsson, Jon Petur Joelsson, Gudmundur H. Gudmundsson
Publikováno v:
ALTEX. 36(4)
Mechanical ventilation (MV) is a life-saving therapy for critically ill patients, alleviating the work of breathing and supporting adequate gas exchange. However, MV can cause ventilator induced lung injury (VILI) by baro/volu- and atelectrauma, even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6877f29326c24c8c7051039c3e5c44
https://pubmed.ncbi.nlm.nih.gov/31210276
https://pubmed.ncbi.nlm.nih.gov/31210276
Autor:
Olafur Baldursson, Ari Jon Arason, Thorarinn Gudjonsson, Skarphedinn Halldorsson, Berglind Eva Benediktsdóttir, Már Másson
Publikováno v:
Pharmaceutical Research. 30:781-791
To determine the integrity and permeability properties of the immortalized human VA10 bronchial epithelial cell line for its suitability as an in vitro drug permeation model.Cells were grown under liquid-covered culture (LCC) or air-liquid interface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063b2c20a0a32c544a0210b265ace8ca
https://doi.org/10.1007/s11095-012-0919-x
https://doi.org/10.1007/s11095-012-0919-x
Autor:
Gunnar Gudmundsson, Bryndis Valdimarsdottir, Magnus K. Magnusson, Ari Jon Arason, Thorarinn Gudjonsson, Helgi J Isaksson
Publikováno v:
1.5 Diffuse Parenchymal Lung Disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27979fe2e728c2e5591167879522cee5
https://doi.org/10.1183/13993003.congress-2015.pa4846
https://doi.org/10.1183/13993003.congress-2015.pa4846