Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ari J. Rosenberg"'
Autor:
Thomas F. Cyberski, Alka Singh, Michael Korzinkin, Vasudha Mishra, Frank Pun, Le Shen, Claudia Wing, Xiangying Cheng, Brandon Baird, Yuxuan Miao, Moshe Elkabets, Sara Kochanny, Wenji Guo, Emma Dyer, Alexander T. Pearson, Aditya Juloori, Mark Lingen, Grayson Cole, Alex Zhavoronkov, Nishant Agrawal, Evgeny Izumchenko, Ari J. Rosenberg
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract The proto-oncogene MYC encodes a nuclear transcription factor that has an important role in a variety of cellular processes, such as cell cycle progression, proliferation, metabolism, adhesion, apoptosis, and therapeutic resistance. MYC ampl
Externí odkaz:
https://doaj.org/article/2a79b91d4c6f452ba91a4478eabc96c9
Autor:
Renata Ferrarotto, Vasudha Mishra, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch, Adi Mondshine, Maria Motin, Tal Leibovich-Rivkin, Matti Davis, Joel Kaye, Christopher R. Weber, Le Shen, Alexander T. Pearson, Ari J. Rosenberg, Xiangying Chen, Alka Singh, Jon C. Aster, Nishant Agrawal, Evgeny Izumchenko
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-11 (2022)
Abstract Adenoid cystic carcinoma (ACC) is an aggressive salivary gland malignancy with limited treatment options for recurrent or metastatic disease. Due to chemotherapy resistance and lack of targeted therapeutic approaches, current treatment optio
Externí odkaz:
https://doaj.org/article/56e0238430084912a4c2eb44ee06b45b
Autor:
Manijeh Goldberg, Aaron Manzi, Peter Conway, Stefanie Cantin, Vasudha Mishra, Alka Singh, Alexander T. Pearson, Eric R. Goldberg, Sam Goldberger, Benjamin Flaum, Rifat Hasina, Nyall R. London, Gary L. Gallia, Chetan Bettegowda, Sonya E. O’Neill, Erkin Aydin, Alex Zhavoronkov, Anxo Vidal, Atenea Soto, Maria Jose Alonso, Ari J. Rosenberg, Mark W. Lingen, Anil D’Cruz, Nishant Agrawal, Evgeny Izumchenko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Cisplatin is the most frequently used chemotherapeutic agent for the treatment of patients with oral cavity squamous cell carcinoma (OCSCC), however, systemic administration is often associated with dose limiting side effects. Here the authors design
Externí odkaz:
https://doaj.org/article/d8848b4e41784c8c9643d35f80e0a0c7
Autor:
Ari J. Rosenberg, Evgeny Izumchenko, Alexander Pearson, Zhen Gooi, Elizabeth Blair, Theodore Karrison, Aditya Juloori, Daniel Ginat, Nicole Cipriani, Mark Lingen, Hillary Sloane, Daniel L. Edelstein, Kirsten Keyser, Johannes Fredebohm, Frank Holtrup, Frederick S. Jones, Daniel Haraf, Nishant Agrawal, Everett E. Vokes
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) has a favorable prognosis which has led to efforts to de-intensify treatment. Response-adaptive de-escalated treatment is promising, however improved biomarkers are
Externí odkaz:
https://doaj.org/article/9a900a0e9acd46aa9f1e55c493688248
Autor:
Manijeh Goldberg, Aaron Manzi, Amritpreet Birdi, Brandon Laporte, Peter Conway, Stefanie Cantin, Vasudha Mishra, Alka Singh, Alexander T. Pearson, Eric R. Goldberg, Sam Goldberger, Benjamin Flaum, Rifat Hasina, Nyall R. London, Gary L. Gallia, Chetan Bettegowda, Simon Young, Vlad Sandulache, James Melville, Jonathan Shun, Sonya E. O’Neill, Erkin Aydin, Alex Zhavoronkov, Anxo Vidal, Atenea Soto, Maria Jose Alonso, Ari J. Rosenberg, Mark W. Lingen, Anil D’Cruz, Nishant Agrawal, Evgeny Izumchenko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1fc932e1d18f416da778b225b7831ccf
Autor:
Daniel Thomas Ginat, Aditya Juloori, Omar I. Vivar, Leonard A. Farber, Zhen Gooi, Ari J. Rosenberg
Publikováno v:
Diagnostics, Vol 12, Iss 9, p 2156 (2022)
NBTXR3 nanoparticle injection is a relatively novel radioenhancer for treatment of various cancers. CT scans following NBTXR3 injection of metastatic lymph nodes from head and neck squamous cell carcinoma were reviewed in a small series of patients.
Externí odkaz:
https://doaj.org/article/0b7f31b516024e678e84ba748f2f36c2
Autor:
Esther C. Broner, Jonathan A. Trujillo, Michael Korzinkin, Tejaswini Subbannayya, Nishant Agrawal, Ivan V. Ozerov, Alex Zhavoronkov, Lisa Rooper, Nikita Kotlov, Le Shen, Alexander T. Pearson, Ari J. Rosenberg, Peter A. Savage, Vasudha Mishra, Aditi Chatterjee, David Sidransky, Evgeny Izumchenko
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Despite recent advancements, the 5 year survival of head and neck squamous cell carcinoma (HNSCC) hovers at 60%. DCLK1 has been shown to regulate epithelial-to-mesenchymal transition as well as serving as a cancer stem cell marker in colon, pancreati
Externí odkaz:
https://doaj.org/article/2050f94809f344348709fe437dccb6db
Autor:
Sankar Jagadeeshan, Manu Prasad, Mai Badarni, Talal Ben-Lulu, Vijayasteltar Belsamma Liju, Sooraj Mathukkada, Claire Saunders, Avital Beeri Shnerb, Jonathan Zorea, Ksenia M. Yegodayev, Monica Wainer, Liza Vtorov, Irit Allon, Ofir Cohen, Gro Gausdal, Dinorah Friedmann-Morvinski, Sok Ching Cheong, Alan L. Ho, Ari J. Rosenberg, Linda Kessler, Francis Burrows, Dexin Kong, Jennifer R. Grandis, J. Silvio Gutkind, Moshe Elkabets
Publikováno v:
Cancer Research. 83:1031-1047
The survival rate for patients with head and neck cancer (HNC) diagnosed with cervical lymph node (cLN) or distant metastasis is low. Genomic alterations in the HRAS oncogene are associated with advanced tumor stage and metastasis in HNC. Elucidation
Autor:
Ari J. Rosenberg, Chih-Yi Liao, Theodore Karrison, Jonas A. de Souza, Francis P. Worden, Bernadette Libao, Monika K. Krzyzanowska, D. Neil Hayes, Eric Winquist, Vassiliki Saloura, Kevin Prescott, Victoria M. Villaflor, Tanguy Y. Seiwert, Rebecca B. Schechter, Walter M. Stadler, Ezra E.W. Cohen, Everett E. Vokes
Publikováno v:
Annals of Oncology.
Autor:
Moshe Elkabets, J. Silvio Gutkind, Jennifer R. Grandis, Dexin Kong, Francis Burrows, Linda Kessler, Ari J. Rosenberg, Alan L. Ho, Sok Ching Cheong, Dinorah Friedmann-Morvinski, Gro Gausdal, Ofir Cohen, Irit Allon, Liza Vtorov, Monica Wainer, Ksenia M. Yegodayev, Jonathan Zorea, Avital Beeri Shnerb, Claire Saunders, Sooraj Mathukkada, Vijayasteltar Belsamma Liju, Talal Ben-Lulu, Mai Badarni, Manu Prasad, Sankar Jagadeeshan
Supplementary Figures S1 to S6 with figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3a403322c503337cd547d6096d80d2
https://doi.org/10.1158/0008-5472.22549775.v1
https://doi.org/10.1158/0008-5472.22549775.v1