Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ariën Schiepers"'
Autor:
Ariën Schiepers, Marije F. L. van ’t Wout, Allison J. Greaney, Trinity Zang, Hiromi Muramatsu, Paulo J. C. Lin, Ying K. Tam, Luka Mesin, Tyler N. Starr, Paul D. Bieniasz, Norbert Pardi, Jesse D. Bloom, Gabriel D. Victora
Publikováno v:
Nature. 615:482-489
Autor:
Ariën Schiepers, Marije F. L. van ’t Wout, Allison J. Greaney, Trinity Zang, Hiromi Muramatsu, Paulo J. C. Lin, Ying K. Tam, Luka Mesin, Tyler N. Starr, Paul D. Bieniasz, Norbert Pardi, Jesse D. Bloom, Gabriel D. Victora
Publikováno v:
bioRxiv
The ability of serum antibody to protect against pathogens arises from the interplay of antigen-specific B cell clones of different affinities and fine specificities. These cellular dynamics are ultimately responsible for serum-level phenomena such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a125943ca8d1f420d4abd1dc7d9e015b
https://europepmc.org/articles/PMC9460965/
https://europepmc.org/articles/PMC9460965/
Autor:
Angelina M. Bilate, Daniel Mucida, Tatsuya Araki, Carla R. Nowosad, Ainsley Lockhart, Christopher Wichmann, Gabriel D. Victora, Gregory P. Donaldson, Luka Mesin, Tiago B. R. Castro, Ariën Schiepers
Publikováno v:
Nature
Germinal centres, the structures in which B cells evolve to produce antibodies with high affinity for various antigens, usually form transiently in lymphoid organs in response to infection or immunization. In lymphoid organs associated with the gut,
Autor:
Leda R. Castilho, Luciana Conde, Alberto Nobrega, Jonas N. Conde, Bruno Maia, Andre M. Vale, Ronaldo Mohana-Borges, Cecilia B. Cavazzoni, Renata G. F. Alvim, Heitor A. Paula Neto, Tostes C V Lucas, Gabriel D. Victora, Iranaia Assunção-Miranda, Rômulo L. S. Neris, Tulio M. Lima, Vicente B. T. Bozza, Diego R. Coelho, Luka Mesin, Jonatan Ersching, Ariën Schiepers
Publikováno v:
The Journal of experimental medicine. 218(9)
Besides antigen-specific responses to viral antigens, humoral immune response in virus infection can generate polyreactive and autoreactive antibodies. Dengue and Zika virus infections have been linked to antibody-mediated autoimmune disorders, inclu
Autor:
Alberto Nobrega, Jonas N. Conde, Jonatan Ersching, Cecilia B. Cavazzoni, Ariën Schiepers, Leda R. Castilho, Heitor A. Paula Neto, Luciana Conde, Gabriel D. Victora, Andre M. Vale, Renata G. F. Alvim, Bruno Maia, Tulio M. Lima, Lucas Tostes, Iranaia Assunção-Miranda, Rômulo L. S. Neris, Diego R. Coelho, Vicente B. T. Bozza, Luka Mesin, Ronaldo Mohana-Borges
Besides antigen-specific responses to viral antigens, humoral immune response in virus infection can generate polyreactive and autoreactive antibodies. Dengue and Zika virus infections have been linked to antibody-mediated autoimmune disorders includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a913fb1e6d48695fa53b7e7e6c216812
https://doi.org/10.1101/2020.12.24.423863
https://doi.org/10.1101/2020.12.24.423863
Autor:
Ariën Schiepers, Sigrid Solem, Alice Galante, Luka Mesin, Johanne T. Jacobsen, Tiago B. R. Castro, Zeran Lin, Angelina M. Bilate, Gabriel D. Victora, Alexander Y. Rudensky, Samuel J. Allon, Alex K. Shalek, Wei Hu
Publikováno v:
Science
Regulating germinal center contractionGerminal centers (GCs) in secondary lymphoid organs are where mature B cells expand and differentiate. Although GC formation is well studied, the control of GC duration and contraction is less well understood. Us
Publikováno v:
Trends in Cancer. 4:715-717
Pediatric neuroblastoma tumors are notorious nonimmunogenic cancers. In contrast to adult tumor types, neuroblastoma cells express low MHC-1, a derivative of its embryonic cell origin expressing little MHC-1. We here address the role of the nuclear f
Autor:
Leo Hanke, Lee Kim Swee, Hidde L. Ploegh, Tao Fang, Juan J. Cragnolini, Jessica R. Ingram, Ali Rashidfarrokhi, Angelina M. Bilate, Justin Bader, Joao N. Duarte, Ariën Schiepers
Publikováno v:
The Journal of Immunology. 197:4838-4847
mAbs specific for surface proteins on APCs can serve as Ag-delivery vehicles that enhance immunogenicity. The practical use of such constructs is limited by the challenge of expressing and modifying full-sized mAbs. We generated single-domain Ab frag
Autor:
Luka Mesin, Alexandru Barbulescu, Ariën Schiepers, Cecilia B. Cavazzoni, Jonatan Ersching, Tomohiro Kurosaki, Gabriel D. Victora, Alessandro Angelini, Takaharu Okada
Publikováno v:
Cell
Summary Repeated exposure to pathogens or their antigens triggers anamnestic antibody responses that are higher in magnitude and affinity than the primary response. These involve reengagement of memory B cell (MBC) clones, the diversity and specifici
Autor:
Styliani Markoulaki, Ariën Schiepers, Rudolf Jaenisch, Gabriel D. Victora, Cecilia B. Cavazzoni, Johanne T. Jacobsen, Luka Mesin, Djenet Bousbaine
Publikováno v:
Rockefeller University Press
The Journal of Experimental Medicine
The Journal of Experimental Medicine
We developed a method for rapid generation of B cell receptor (BCR) monoclonal mice expressing prerearranged Igh and Igk chains monoallelically from the Igh locus by CRISPR-Cas9 injection into fertilized oocytes. B cells from these mice undergo somat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266e435985b0c1683c0707afccc74aa7
http://hdl.handle.net/10852/72036
http://hdl.handle.net/10852/72036