Roxadustat alleviates metabolic traits in letrozole-induced PCOS mice.

Autor: Virtanen N; Department of Obstetrics and Gynecology, Medical Research Centre, Research Unit of Clinical Medicine, University of Oulu, Oulu University Hospital, Oulu, Finland; Research Unit of Extracellular Matrix and Hypoxia, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland., Saarela U; Department of Obstetrics and Gynecology, Medical Research Centre, Research Unit of Clinical Medicine, University of Oulu, Oulu University Hospital, Oulu, Finland., Karpale M; Research Unit of Extracellular Matrix and Hypoxia, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland., Arffman RK; Department of Obstetrics and Gynecology, Medical Research Centre, Research Unit of Clinical Medicine, University of Oulu, Oulu University Hospital, Oulu, Finland., Mäkelä KA; Research Unit of Biomedicine and Internal Medicine, Biocenter Oulu, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Herzig KH; Research Unit of Biomedicine and Internal Medicine, Biocenter Oulu, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Koivunen P; Research Unit of Extracellular Matrix and Hypoxia, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland., Piltonen T; Department of Obstetrics and Gynecology, Medical Research Centre, Research Unit of Clinical Medicine, University of Oulu, Oulu University Hospital, Oulu, Finland. Electronic address: terhi.piltonen@oulu.fi.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2024 Nov; Vol. 229, pp. 116522. Date of Electronic Publication: 2024 Sep 06.

Human Endometrial Pericytes: A Comprehensive Overview of Their Physiological Functions and Implications in Uterine Disorders.

Autor: Tang Y; WHO Collaborating Centre, Division of Neonatology, Obstetrics, Gynecology, and Reproductive Health, Department of Women's and Children's Health, Karolinska University Hospital, Karolinska Institutet, SE 17176 Stockholm, Sweden.; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Centre, Oulu University Hospital, University of Oulu, 90220 Oulu, Finland., Frisendahl C; WHO Collaborating Centre, Division of Neonatology, Obstetrics, Gynecology, and Reproductive Health, Department of Women's and Children's Health, Karolinska University Hospital, Karolinska Institutet, SE 17176 Stockholm, Sweden., Piltonen TT; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Centre, Oulu University Hospital, University of Oulu, 90220 Oulu, Finland., Arffman RK; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Centre, Oulu University Hospital, University of Oulu, 90220 Oulu, Finland., Lalitkumar PG; WHO Collaborating Centre, Division of Neonatology, Obstetrics, Gynecology, and Reproductive Health, Department of Women's and Children's Health, Karolinska University Hospital, Karolinska Institutet, SE 17176 Stockholm, Sweden., Gemzell-Danielsson K; WHO Collaborating Centre, Division of Neonatology, Obstetrics, Gynecology, and Reproductive Health, Department of Women's and Children's Health, Karolinska University Hospital, Karolinska Institutet, SE 17176 Stockholm, Sweden.

Publikováno v: Cells [Cells] 2024 Sep 09; Vol. 13 (17). Date of Electronic Publication: 2024 Sep 09.

Association of Accelerometer-Determined Physical Activity and Sedentary Behavior With the Gut Microbiome in Middle-Aged Women: A Compositional Data Approach.

Autor: Pérez-Prieto I; Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain., Migueles JH; Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain., Molina NM; Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain., Sola-Leyva A; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden.; Competence Centre on Health Technologies, Tartu, Estonia., Salas-Espejo E; Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada, Spain., Arffman RK; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Nurkkala M; Department of Sports and Exercise Medicine, Oulu Deaconess Institute Foundation sr, Oulu, Finland.; Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland., Niemelä M; Research Unit of Health Sciences and Technology, Medical Faculty, University of Oulu, Oulu, Finland., Lüll K; Institute of Genomics, Estonian Genome Centre, University of Tartu, Tartu, Estonia., Org E; Institute of Genomics, Estonian Genome Centre, University of Tartu, Tartu, Estonia., Franks S; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Tapanainen JS; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Obstetrics and Gynaecology, HFR - Cantonal Hospital of Fribourg and University of Fribourg, Fribourg, Switzerland., Salumets A; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden.; Competence Centre on Health Technologies, Tartu, Estonia.; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia., Piltonen TT; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Ortega FB; Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.; CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Granada, Spain.; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Altmäe S; Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain.; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden.

Publikováno v: Scandinavian journal of medicine & science in sports [Scand J Med Sci Sports] 2024 Jul; Vol. 34 (7), pp. e14689.

Gut bacteriome and mood disorders in women with PCOS.

Autor: Lee S; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia., Tejesvi MV; Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland.; Ecology and Genetics, University of Oulu, Oulu, Finland., Hurskainen E; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Aasmets O; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Plaza-Díaz J; Faculty of Pharmacy, Department of Biochemistry and Molecular Biology II, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria ibs. GRANADA, Granada, Spain.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Canada., Franks S; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Morin-Papunen L; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Tapanainen JS; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Obstetrics and Gynaecology, HFR-Cantonal Hospital of and University of Fribourg, Fribourg, Switzerland., Ruuska TS; Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland.; Department of Pediatrics and Adolescent Medicine and Medical Research Center, Oulu University Hospital, Oulu, Finland., Altmäe S; Faculty of Pharmacy, Department of Biochemistry and Molecular Biology II, University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria ibs. GRANADA, Granada, Spain.; Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden., Org E; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Salumets A; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.; Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden.; Competence Centre on Health Technologies, Tartu, Estonia., Arffman RK; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Piltonen TT; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.

Publikováno v: Human reproduction (Oxford, England) [Hum Reprod] 2024 Jun 03; Vol. 39 (6), pp. 1291-1302.

AI-algorithm training and validation for identification of endometrial CD138+ cells in infertility-associated conditions; polycystic ovary syndrome (PCOS) and recurrent implantation failure (RIF).

Autor: Lee S; Department of Obstetrics and Gynaecology, Medical Research Center Oulu, Research Unit of Clinical Medicine, University of Oulu and Oulu University Hospital, Oulu 90220, Finland.; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu 50406, Estonia., Arffman RK; Department of Obstetrics and Gynaecology, Medical Research Center Oulu, Research Unit of Clinical Medicine, University of Oulu and Oulu University Hospital, Oulu 90220, Finland., Komsi EK; Department of Obstetrics and Gynaecology, Medical Research Center Oulu, Research Unit of Clinical Medicine, University of Oulu and Oulu University Hospital, Oulu 90220, Finland., Lindgren O; Department of Pathology, Oulu University Hospital, Cancer and Translational Medicine Research Unit, University of Oulu, Oulu 90220, Finland., Kemppainen JA; Department of Pathology, Oulu University Hospital, Cancer and Translational Medicine Research Unit, University of Oulu, Oulu 90220, Finland., Metsola H; Department of Pathology, Oulu University Hospital, Cancer and Translational Medicine Research Unit, University of Oulu, Oulu 90220, Finland., Rossi HR; Department of Obstetrics and Gynaecology, Medical Research Center Oulu, Research Unit of Clinical Medicine, University of Oulu and Oulu University Hospital, Oulu 90220, Finland., Ahtikoski A; Department of Pathology, Turku University Hospital, Turku 20521, Finland., Kask K; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu 50406, Estonia.; Competence Centre on Health Technologies, Tartu 51014, Estonia., Saare M; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu 50406, Estonia.; Competence Centre on Health Technologies, Tartu 51014, Estonia., Salumets A; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu 50406, Estonia.; Competence Centre on Health Technologies, Tartu 51014, Estonia.; Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology, Karolinska Institute and Karolinska University Hospital, Stockholm 14152, Sweden., Piltonen TT; Department of Obstetrics and Gynaecology, Medical Research Center Oulu, Research Unit of Clinical Medicine, University of Oulu and Oulu University Hospital, Oulu 90220, Finland.

Publikováno v: Journal of pathology informatics [J Pathol Inform] 2024 Apr 29; Vol. 15, pp. 100380. Date of Electronic Publication: 2024 Apr 29 (Print Publication: 2024).